Structure of a biological oxygen sensor: A new mechanism for heme-driven signal transduction

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Stereochemistry of Cooperative Effects in Haemoglobin: Haem–Haem Interaction and the Problem of Allostery

1970 • 2,874 citations

Raster3D Version 2.0. A program for photorealistic molecular graphics

1994 • 2,515 citations

COMMUNICATION MODULES IN BACTERIAL SIGNALING PROTEINS

1992 • 1,449 citations

Mechanism of NO-Induced Oxidation of Myoglobin and Hemoglobin

1996 • 609 citations

Mechanisms of cooperativity and allosteric regulation in proteins

1990 • 514 citations

The Drosophila single-minded gene encodes a helix-loop-helix protein that acts as a master regulator of CNS midline development

1991 • 501 citations

Practical Protein Crystallography

1999 • 496 citations

A haemoprotein with kinase activity encoded by the oxygen sensor of Rhizobium meliloti

1991 • 477 citations

Assessment of phase accuracy by cross validation: the free R value. Methods and applications

1993 • 451 citations

Cascade regulation of nif gene expression in Rhizobium meliloti

1988 • 415 citations

Crystallographic refinement by simulated annealing

1988 • 411 citations

PAS domain S-boxes in archaea, bacteria and sensors for oxygen and redox

1997 • 410 citations

Structure of a Protein Photocycle Intermediate by Millisecond Time-Resolved Crystallography

1997 • 406 citations

High-Resolution Crystal Structures of Distal Histidine Mutants of Sperm Whale Myoglobin

1993 • 386 citations

Guanylyl cyclase receptors.

1994 • 292 citations

Myoglobin discriminates between O2, NO, and CO by electrostatic interactions with the bound ligand

1997 • 283 citations

[31] PHASES-95: A program package for processing and analyzing diffraction data from macromolecules

1997 • 255 citations

Heme-Based Sensors, Exemplified by the Kinase FixL, Are a New Class of Heme Protein with Distinctive Ligand Binding and Autoxidation

1994 • 239 citations

Photoactive yellow protein: A structural prototype for the three-dimensional fold of the PAS domain superfamily

1998 • 230 citations

CooA, a CO-sensing transcription factor from Rhodospirillum rubrum , is a CO-binding heme protein

1997 • 186 citations

Azotobacter vinelandii NIFL is a flavoprotein that modulates transcriptional activation of nitrogen-fixation genes via a redox-sensitive switch.

1996 • 177 citations

The FixL protein of Rhizobium meliloti can be separated into a heme-binding oxygen-sensing domain and a functional C-terminal kinase domain.

1992 • 165 citations

Crystal structures of a nitric oxide transport protein from a blood-sucking insect

1998 • 154 citations

Regulation of the kinase activity of heme protein FixL from the two-component system FixL/FixJ of Rhizobium meliloti

1993 • 122 citations

The regulatory status of the fixL- and fixJ-like genes in Bradyrhizobium japonicum may be different from that in Rhizobium meliloti

1991 • 118 citations

Kinase Activity of Oxygen Sensor FixL Depends on the Spin State of Its Heme Iron

1995 • 107 citations

Sequence and molecular analysis of the nifL gene of Azotobacter vinelandii

1993 • 92 citations

Oxygen-regulated in vitro transcription of Rhizobium meliloti nifA and fixK genes

1993 • 87 citations

Oxygen regulation of nifA transcription in vitro.

1993 • 62 citations

Structural Basis for Ligand Discrimination and Response Initiation in the Heme-Based Oxygen Sensor FixL

1996 • 49 citations

Nonsteric factors dominate binding of nitric oxide, azide, imidazole, cyanide, and fluoride to the Rhizobial heme-based oxygen sensor FixL

1996 • 48 citations

Glycera dibranchiata hemoglobin structure and refinement at 1·5resolution

1990 • 47 citations

Glycera dibranchiata hemoglobin

1989 • 46 citations

Nature of Endogenous Ligand Binding to Heme Iron in Oxygen Sensor FixL

1996 • 46 citations

Characterization of a second gene involved in bacterio-opsin gene expression in a halophilic archaebacterium

1988 • 38 citations

Assessment of bulk solvent models by cross-validation

1993 • 37 citations

Imidazole Is a Sensitive Probe of Steric Hindrance in the Distal Pockets of Oxygen-Binding Heme Proteins

1998 • 34 citations

Assignment of the hyperfine-shifted 1H-NMR signals of the heme in the oxygen sensor FixL from Rhizobium meliloti

1996 • 18 citations