Insights into eukaryotic multistep phosphorelay signal transduction revealed by the crystal structure of Ypd1p from Saccharomyces cerevisiae

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

AMoRe: an automated package for molecular replacement

1994 • 4,990 citations

Protein Structure Comparison by Alignment of Distance Matrices

1993 • 3,989 citations

[26] Raster3D: Photorealistic molecular graphics

1997 • 3,784 citations

[16] SHELXL: High-resolution refinement

1997 • 2,469 citations

An Osmosensing Signal Transduction Pathway in Yeast

1993 • 1,252 citations

ALSCRIPT: a tool to format multiple sequence alignments

1993 • 1,125 citations

Yeast HOG1 MAP Kinase Cascade Is Regulated by a Multistep Phosphorelay Mechanism in the SLN1–YPD1–SSK1 “Two-Component” Osmosensor

1996 • 876 citations

Initiation of sporulation in B. subtilis is controlled by a multicomponent phosphorelay

1991 • 870 citations

Two-Component Signal Transduction

1995 • 752 citations

Activation of Yeast PBS2 MAPKK by MAPKKKs or by Binding of an SH3-Containing Osmosensor

1995 • 649 citations

Two-component signal transduction

1995 • 502 citations

Structure of CheA, a Signal-Transducing Histidine Kinase

1999 • 471 citations

A Yeast Protein Similar to Bacterial Two-Component Regulators

1993 • 431 citations

Structural conservation in the CheY superfamily

1993 • 288 citations

Two-component signal transducers and MAPK cascades

1997 • 288 citations

His-Asp Phosphotransfer Signal Transduction

1998 • 215 citations

Solution structure of the 40,000 Mr phosphoryl transfer complex between the N-terminal domain of enzyme I and HPr.

1999 • 212 citations

The yeast histidine protein kinase, Sln1p, mediates phosphotransfer to two response regulators, Ssk1p and Skn7p

1998 • 183 citations

Histidine and aspartate phosphorylation: two-component systems and the limits of homology

1994 • 181 citations

Histidine kinases in signal transduction pathways of eukaryotes

1997 • 173 citations

Signal transduction via the histidyl‐aspartyl phosphorelay

1997 • 165 citations

Insights into Multistep Phosphorelay from the Crystal Structure of the C-Terminal HPt Domain of ArcB

1997 • 159 citations

Antibacterial agents that inhibit two-component signal transduction systems

1998 • 123 citations

Formation of a Novel Four-Helix Bundle and Molecular Recognition Sites by Dimerization of a Response Regulator Phosphotransferase

1998 • 108 citations

Molecular replacement

1992 • 92 citations

PBS2, a yeast gene encoding a putative protein kinase, interacts with the RAS2 pathway and affects osmotic sensitivity of Saccharomyces cerevisiae

1992 • 89 citations

Yeast Skn7p activity is modulated by the Sln1p-Ypd1p osmosensor and contributes to regulation of the HOG pathway

1998 • 83 citations

Phosphotransfer Site of the Chemotaxis-Specific Protein Kinase CheA as Revealed by NMR

1997 • 54 citations

Eukaryotes have “two-component” signal tranducers

1994 • 39 citations

Signal Transduction: Bringing the eukaryotes up to speed

1994 • 26 citations

Large-Format Imaging Plate and Weissenberg Camera for Accurate Protein Crystallographic Data Collection Using Synchrotron Radiation

1997 • 14 citations

Purification, crystallization and preliminary X-ray diffraction analysis of the yeast phosphorelay protein YPD1

1999 • 13 citations

Crystallization and preliminary X-ray analysis of Saccharomyces cerevisiae Ypd1p, a key intermediate in phosphorelay signal transduction

1999 • 2 citations