A Proteomic Approach for the Identification of Cell-surface Proteins Shed by Metalloproteases

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

1996 • 8,994 citations

Probability-based protein identification by searching sequence databases using mass spectrometry data

1999 • 8,138 citations

A Receptor-Mediated Pathway for Cholesterol Homeostasis

1986 • 5,638 citations

A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids

1984 • 3,959 citations

A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells

1997 • 3,094 citations

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α

1997 • 1,608 citations

An Essential Role for Ectodomain Shedding in Mammalian Development

1998 • 1,607 citations

Evaluation of two-dimensional gel electrophoresis-based proteome analysis technology

2000 • 1,323 citations

A Novel Proteolytic Cleavage Involved in Notch Signaling

2000 • 1,080 citations

Evidence That Tumor Necrosis Factor α Converting Enzyme Is Involved in Regulated α-Secretase Cleavage of the Alzheimer Amyloid Protein Precursor

1998 • 922 citations

Episomal Vectors Rapidly and Stably Produce High-Titer Recombinant Retrovirus

1996 • 768 citations

Membrane protein secretases

1997 • 634 citations

Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing

1994 • 607 citations

Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding

1999 • 558 citations

Functional Analysis of the Domain Structure of Tumor Necrosis Factor-α Converting Enzyme

2000 • 496 citations

ADAMs: focus on the protease domain

1998 • 472 citations

Shedding as a mechanism of down-modulation of CD14 on stimulated human monocytes.

1991 • 427 citations

Remarkable roles of proteolysis on and beyond the cell surface

2000 • 235 citations

The LDL Receptor Gene Family

2001 • 230 citations

Metalloproteolytic Release of Endothelial Cell Protein C Receptor

2000 • 184 citations

The Receptor Tyrosine Kinase ARK Mediates Cell Aggregation by Homophilic Binding

1995 • 179 citations

Shedding of interleukin-6 receptor and tumor necrosis factor α

2000 • 168 citations

TNF-α-Converting Enzyme Cleaves the Macrophage Colony-Stimulating Factor Receptor in Macrophages Undergoing Activation

2001 • 150 citations

SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility

2000 • 143 citations

Tumor Necrosis Factor-α Converting Enzyme (TACE) Is a Growth Hormone Binding Protein (GHBP) Sheddase: The Metalloprotease TACE/ADAM-17 Is Critical for (PMA-Induced) GH Receptor Proteolysis and GHBP Generation*

2000 • 139 citations

The importance of shedding of membrane proteins for cytokine biology.

2000 • 122 citations

Shedding of c-Met is regulated by crosstalk between a G-protein coupled receptor and the EGF receptor and is mediated by a TIMP-3 sensitive metalloproteinase

2014 • 112 citations

Shedding of c-Met is regulated by crosstalk between a G-protein coupled receptor and the EGF receptor and is mediated by a TIMP-3 sensitive metalloproteinase

2001 • 105 citations

CD30 Shedding from Karpas 299 Lymphoma Cells Is Mediated by TNF-α-Converting Enzyme

2000 • 101 citations

Ectodomain shedding, translocation and synthesis of SorLA are stimulated by its ligand head activator

2000 • 71 citations

Probing proteomes—seeing the whole picture?

2000 • 47 citations