Temporal and Distinct TGFβ Ligand Requirements during Mouse and Avian Endocardial Cushion Morphogenesis

Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse.

1995 • 1,782 citations

TGFβ2 knockout mice have multiple developmental defects that are non-overlapping with other TGFβ knockout phenotypes

1997 • 1,404 citations

Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knock out mice

1995 • 1,020 citations

Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development

1996 • 959 citations

Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme

2000 • 864 citations

Incidence of congenital heart disease: I. Postnatal incidence

1995 • 780 citations

Molecular Regulation of Atrioventricular Valvuloseptal Morphogenesis

1995 • 642 citations

Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for Bone Morphogenetic Protein-2A (BMP-2A)

1990 • 616 citations

Incidence of congenital heart disease: II. Prenatal incidence

1995 • 390 citations

Requirement of Type III TGF-β Receptor for Endocardial Cell Transformation in the Heart

1999 • 376 citations

The anatomical basis of mouse development

1999 • 370 citations

Pathogenesis of cleft palate in TGF-β3 knockout mice

1999 • 328 citations

TheCspg2Gene, Disrupted in thehdfMutant, Is Required for Right Cardiac Chamber and Endocardial Cushion Formation

1998 • 318 citations

Double-Outlet Right Ventricle and Overriding Tricuspid Valve Reflect Disturbances of Looping, Myocardialization, Endocardial Cushion Differentiation, and Apoptosis in TGF-β ₂ –Knockout Mice

2001 • 302 citations

Invasion of mesenchyme into three-dimensional collagen gels: A regional and temporal analysis of interaction in embryonic heart tissue

1983 • 265 citations

Epithelial-mesenchymal transformation of embryonic cardiac endothelial cells is inhibited by a modified antisense oligodeoxynucleotide to transforming growth factor beta 3.

1991 • 263 citations

Developmental landmarks in cardiac morphogenesis: Comparative chronology

1970 • 249 citations

A novel role for VEGF in endocardial cushion formation and its potential contribution to congenital heart defects

2001 • 236 citations

TGFβ2 and TGFβ3 Have Separate and Sequential Activities during Epithelial–Mesenchymal Cell Transformation in the Embryonic Heart

1999 • 201 citations

Neurofibromin modulation of ras activity is required for normal endocardial-mesenchymal transformation in the developing heart

1998 • 180 citations

RNA and protein localisations of TGFβ2 in the early mouse embryo suggest an involvement in cardiac development

1993 • 166 citations

Antibodies to the Type II TGFβ Receptor Block Cell Activation and Migration during Atrioventricular Cushion Transformation in the Heart

1996 • 126 citations

Extracellular Fibrillar Structure of Latent TGFβ Binding Protein-1: Role in TGFβ-dependent Endothelial-Mesenchymal Transformation during Endocardial Cushion Tissue Formation in Mouse Embryonic Heart

1997 • 123 citations

Transforming growth factor-β1–deficient mice: identification of isoform-specific activities in vivo

1996 • 81 citations

Structural analysis of cell: Matrix association during the morphogenesis of atrioventricular cushion tissue

1979 • 80 citations

Mechanisms of Fibroblast Growth Factor-2 Modulation of Vascular Endothelial Growth Factor Expression by Osteoblastic Cells

2000 • 77 citations

Bone morphogenetic protein-2 acts synergistically with transforming growth factor-?3 during endothelial-mesenchymal transformation in the developing chick heart

1999 • 76 citations

Myocardial Regulation of Transforming Growth Factor-β Expression by Outflow Tract Endothelium in the Early Embryonic Chick Heart

1994 • 72 citations

Effects of hyaluronic acid on cardiac cushion tissue cells in collagen matrix cultures.

1979 • 72 citations

Activin receptor-like kinase 2 can mediate atrioventricular cushion transformation

2000 • 65 citations

TGF-β in the Cardiovascular System Molecular Mechanisms of a Context-Specific Growth Factor

2000 • 47 citations

TGFβ Type III and TGFβ Type II receptors have distinct activities during epithelial–mesenchymal cell transformation in the embryonic heart

2001 • 45 citations

Differential expression of α6 and other subunits of laminin binding integrins during development of the murine heart

1996 • 41 citations

Congenital cardiovascular malformations in the Baltimore-Washington area.

1985 • 23 citations