Expression and induction of the stress protein alpha-B-crystallin in vascular endothelial cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium.

1986 • 7,740 citations

Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polycrylamide to nitrocellulose

1984 • 2,553 citations

Alpha-crystallin can function as a molecular chaperone.

1992 • 1,822 citations

A safe packaging line for gene transfer: separating viral genes on two different plasmids

1988 • 1,118 citations

Cardiac stress protein elevation 24 hours after brief ischemia or heat stress is associated with resistance to myocardial infarction.

1993 • 1,005 citations

Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury.

1995 • 859 citations

Four small Drosophila heat shock proteins are related to each other and to mammalian alpha-crystallin.

1982 • 792 citations

Transgenic mice expressing the human heat shock protein 70 have improved post-ischemic myocardial recovery.

1995 • 558 citations

αB subunit of lens-specific protein α-crystallin is present in other ocular and non-ocular tissues

1989 • 538 citations

Alpha B-crystallin is a small heat shock protein.

1991 • 526 citations

Heat-shock response is associated with enhanced postischemic ventricular recovery.

1988 • 489 citations

Chaperone activity of alpha-crystallins modulates intermediate filament assembly.

1994 • 415 citations

Expression of the murine alpha B-crystallin gene is not restricted to the lens.

1989 • 377 citations

Intermediate filament interactions can be altered by HSP27 and αB-crystallin

1999 • 359 citations

Small Heat Shock Proteins and Protection Against Ischemic Injury in Cardiac Myocytes

1997 • 345 citations

Cellular distribution of alpha B-crystallin in non-lenticular tissues.

1990 • 295 citations

Transgene overexpression of αB crystallin confers simultaneous protection against cardiomyocyte apoptosis and necrosis during myocardial ischemia and reperfusion

2001 • 217 citations

Stress fibers in the splenic sinus endothelium in situ: molecular structure, relationship to the extracellular matrix, and contractility.

1986 • 195 citations

Ischemic preconditioning protects against coronary endothelial dysfunction induced by ischemia and reperfusion.

1994 • 190 citations

Improved in vitro rheological system for studying the effect of fluid shear stress on cultured cells

1993 • 184 citations

αβ-crystallin interacts with intermediate filaments in response to stress

1997 • 167 citations

Expression of the murine small heat shock proteins hsp 25 and alpha B crystallin in the absence of stress.

1993 • 163 citations

Bacterial exotoxins and endothelial permeability for water and albumin in vitro

1988 • 127 citations

αB-Crystallin Expression in Mouse NIH 3T3 Fibroblasts: Glucocorticoid Responsiveness and Involvement in Thermal Protection

1993 • 126 citations

Coordinate and independent regulation of αB‐crystallin and HSP27 expression in response to physiological stress

1994 • 119 citations

Ischemia-induced phosphorylation and translocation of stress protein αB-crystallin to Z lines of myocardium

1998 • 107 citations

Ceramide formation during heat shock: a potential mediator of alpha B-crystallin transcription.

1995 • 98 citations

Ischaemic preconditioning of the vasculature: an overlooked phenomenon for protecting the heart?

2000 • 93 citations

Binding of Cytosolic Proteins to Myofibrils in Ischemic Rat Hearts

1996 • 89 citations

Binding of the Stress ProteinαB-crystallin to Cardiac Myofibrils Correlates with the Degree of Myocardial Damage During Ischemia/Reperfusionin vivo

1999 • 87 citations

Adaptive Responses of the Endothelium to Stress

2000 • 82 citations

Cardiac alpha-crystallin

1990 • 79 citations

Protein phosphatase inhibitors and heat preconditioning prevent Hsp27 dephosphorylation, F‐actin disruption and deterioration of morphology in ATP‐depleted endothelial cells

1998 • 59 citations

Translocation and induction of αB crystallin by heat shock in rat glioma (GA-1) cells

1992 • 55 citations

Mechanisms of protection afforded by preconditioning to endothelial function against ischemic injury

1996 • 52 citations

Early and delayed tolerance to simulated ischemia in heat-preconditioned endothelial cells: a role for HSP27

1998 • 43 citations

Heat Shock Provides Delayed Protection against Oxidative Injury in Cultured Human Umbilical Vein Endothelial Cells

1998 • 40 citations

Differences in laminin fragment interactions of normal and transformed endothelial cells

1991 • 35 citations

A NEW METHOD FOR THE QUANTITATIVE DETERMINATION OF ANTIBODY AND ANTIGEN PROTEIN, WITH A SENSITIVITY TO FIVE MICROGRAMS.

1965 • 34 citations

Correlation of endothelial vimentin content with hemodynamic parameters

1998 • 32 citations

Enhancement of stress-induced synthesis of hsp27 and αB crystallin by modulators of the arachidonic acid cascade

1996 • 28 citations

Identification of stress proteins in endothelial cells

1996 • 23 citations

Effects of hyperthermia on cell survival and patterns of protein synthesis in endothelial cells from different origins.

1988 • 22 citations

Modulation of the Stress-Induced Synthesis of Stress Proteins by a Phorbol Ester and Okadaic Acid1

1995 • 21 citations

αB-Crystallin Accumulation in Human Astroglioma Cell Line U373MG Is Stress-Dependent and Phosphorylation-Independent

1994 • 12 citations