Back to search

Hepatic encephalopathy in chronic liver disease: a clinical manifestation of astrocyte swelling and low-grade cerebral edema?

Data up to Jan 2025

Published2000
Citations453
References40

Total Citations Per Year

Abstract

References (40)

Functional Significance of Cell Volume Regulatory Mechanisms

1998 • 1,871 citations

Glutamine Synthetase: Glial Localization in Brain

1977 • 1,170 citations

Direct Signaling from Astrocytes to Neurons in Cultures of Mammalian Brain Cells

1994 • 1,000 citations

The role of cellular hydration in the regulation of cell function

1996 • 571 citations

Treatment of Hepatic Encephalopathy

1997 • 485 citations

Proton magnetic resonance spectroscopy studies on human brain Myo-inositol in hypo-osmolarity and hepatic encephalopathy

1994 • 413 citations

Current concepts of brain edema

1995 • 412 citations

Ammonia: Key factor in the pathogenesis of hepatic encephalopathy

1987 • 397 citations

Molecular basis of osmotic regulation

1995 • 371 citations

Cerebral Ammonia Metabolism in Patients with Severe Liver Disease and Minimal Hepatic Encephalopathy

1991 • 328 citations

Ammonia-induced brain edema and intracranial hypertension in rats after portacaval anastomosis

1994 • 236 citations

Proton magnetic resonance spectroscopy of the brain in symptomatic and asymptomatic patients with liver cirrhosis

1997 • 216 citations

Subclinical hepatic encephalopathy: proton MR spectroscopic abnormalities.

1994 • 212 citations

Pathophysiology of cerebral edema in fulminant hepatic failure

1999 • 201 citations

Astrocytes : pharmacology and function

1993 • 199 citations

Ammonia-induced astrocyte swelling in primary culture

1991 • 184 citations

Cerebral oedema and increased intracranial pressure in chronic liver disease

1998 • 178 citations

Astrocytic-Ammonia Interactions in Hepatic Encephalopathy

1996 • 176 citations

The Neurobiology of Hepatic Encephalopathy

1996 • 170 citations

Glutamine,myo-inositol, and organic brain osmolytes after portocaval anastomosis in the rat: Implications for ammonia-induced brain edema

1996 • 167 citations

Ammonia and GABA-ergic neurotransmission: Interrelated factors in the pathogenesis of hepatic encephalopathy

1997 • 135 citations

Calcium-dependent activation of Erk-1 and Erk-2 after hypo-osmotic astrocyte swelling

1996 • 104 citations

Effect of benzodiazepines and neurosteroids on ammonia-induced swelling in cultured astrocytes

1998 • 92 citations

Osmoregulation of Na(+)-inositol cotransporter activity and mRNA levels in brain glial cells

1992 • 89 citations

Proton Magnetic Resonance Spectroscopy: The New Gold Standard for Diagnosis of Clinical and Subclinical Hepatic Encephalopathy?

1996 • 84 citations

Osmotic Induction of Signaling Cascades: Role in Regulation of Cell Function

1999 • 70 citations

Proton‐Decoupled 31P Magnetic Resonance Spectroscopy Reveals Osmotic and Metabolic Disturbances in Human Hepatic Encephalopathy

1998 • 66 citations

Characterization of the hypo-osmolarity-induced Ca2+ response in cultured rat astrocytes

1997 • 56 citations

Chapter 22: Hepatic encephalopathy: a disorder in glial-neuronal communication

1992 • 54 citations

Current concepts in the pathophysiology of hepatic encephalopathy

1992 • 51 citations

pathogenesis and treatment of chronic hepatic encephalopathy

1996 • 43 citations

Hepatic Encephalopathy

1986 • 42 citations

Decrease in cerebral inositols in rats and humans

1993 • 41 citations

Effect of osmolality and anion channel inhibitors on myo-inositol efflux in cultured astrocytes

1999 • 38 citations

Multinuclear NMR Spectroscopy Studies on NH<sub>4</sub>Cl-Induced Metabolic Alterations and Detoxification Processes in Primary Astrocytes and Glioma Cells

1998 • 38 citations

Effect of astroglial cell swelling on pH of acidic intracellular compartments

1996 • 34 citations

Effect of hypoosmotic stress on peripheral-type benzodiazepine receptors in cultured astrocytes

1994 • 27 citations

Liver and Nervous System

1998 • 21 citations

Liver and Nervous System

1998 • 14 citations

Hepatic encephalopathy

1993 • 9 citations

Cited By (0)

Loading...
Hepatic encephalopathy in chronic liver disease: a clinical manifestation of astrocyte… (2000) – Journal of Hepatology | Metascience Observatory Explorer