Low expression of human histocompatibility leukocyte antigen-DR is associated with hypermethylation of human histocompatibility leukocyte antigen-DR alpha gene regions in B cells from patients with systemic lupus erythematosus.

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

DNA Methylation and Gene Function

1980 • 2,069 citations

DNA METHYLATION AND GENE ACTIVITY

1983 • 1,115 citations

Two populations of Ia-like molecules on a human B cell line.

1980 • 1,112 citations

5-Methylcytosine in Eukaryotic DNA

1981 • 744 citations

Role of MHC Gene Products in Immune Regulation

1981 • 705 citations

Etiopathogenesis of Murine SLE¹

1981 • 517 citations

DNA methylation and the regulation of globin gene expression

1983 • 451 citations

Effects of Corticosteroids on Immunity in Man I. DECREASED SERUM IgG CONCENTRATION CAUSED BY 3 OR 5 DAYS OF HIGH DOSES OF METHYLPREDNISOLONE

1973 • 331 citations

Complete amino acid sequence of an HLA-DR antigen-like beta chain as predicted from the nucleotide sequence: similarities with immunoglobulins and HLA-A, -B, and -C antigens.

1982 • 320 citations

Methylation of the hypoxanthine phosphoribosyltransferase locus on the human X chromosome: implications for X-chromosome inactivation.

1984 • 305 citations

Complete sequence of an HLA-dR beta chain deduced from a cDNA clone and identification of multiple non-allelic DR beta chain genes.

1983 • 271 citations

A systemic lupus erythematosus (SLE)‐like disease in mice induced by abnormal T‐B cell cooperation. Preferential formation of autoantibodies characteristic of SLE

1982 • 267 citations

Autoimmunity - A Perspective

1983 • 260 citations

The Major Histocompatibility Complex in Man

1981 • 229 citations

Increased Circulating Ia-Antigen-Bearing T Cells in Type I Diabetes Mellitus

1982 • 227 citations

Systemic Lupus Erythematosus: Evolving Concepts

1979 • 210 citations

Nature of cold‐reactive antibodies to lymphocyte surface determinants in systemic lupus erythematosus

1975 • 202 citations

The Cellular and Genetic Basis of Murine Lupus

1981 • 195 citations

Epstein-Barr virus susceptibility of normal human B lymphocyte populations.

1984 • 193 citations

Distribution of 5-methylcytosine in pyrimidine sequences of deoxyribonucleic acids

1962 • 193 citations

Identification of a B cell differentiation factor(s) spontaneously produced by proliferating T cells in murine lupus strains of the lpr/lpr genotype.

1983 • 188 citations

Gene expression: DNA methylation — how important in gene control?

1984 • 178 citations

Induction of murine autoimmune disease by chronic polyclonal B cell activation.

1983 • 171 citations

Circulating and pokeweed mitogen-induced immunoglobulin-secreting cells in systemic lupus erythematosus.

1979 • 170 citations

Molecular mechanisms of human hemoglobin switching: selective undermethylation and expression of globin genes in embryonic, fetal, and adult erythroblasts.

1983 • 136 citations

Structure and nucleotide sequence of the heavy chain gene of HLA-DR.

1983 • 132 citations

The amino acid sequence and gene organization of the heavy chain of the HLA-DR antigen: homology to immunoglobulins.

1982 • 121 citations

Biosynthesis and Regulation of Immunoglobulins

1983 • 119 citations

B cell dependence on and response to accessory signals in murine lupus strains.

1983 • 108 citations

Genomic rearrangements in a mouse cell line containing integrated SV40 DNA

1981 • 108 citations

DNA methylation of three 5' C-C-G-G 3' sites in the promoter and 5' region inactivate the E2a gene of adenovirus type 2.

1984 • 105 citations

Epstein–Barr virus transforms precursor B cells even before immunoglobulin gene rearrangements

1984 • 105 citations

Methylation patterns of immunoglobulin genes in lymphoid cells: correlation of expression and differentiation with undermethylation.

1983 • 101 citations

Differentiation of two mouse cell lines is associated with hypomethylation of their genomes.

1984 • 96 citations

Isolation of cDNA clones encoding HLA-DR alpha chains.

1982 • 92 citations

Isolation of DNA from DNA/anti-DNA antibody immune complexes in systemic lupus erythematosus.

1981 • 86 citations

Methylation of simian virus 40 Hpa II site affects late, but not early, viral gene expression.

1982 • 85 citations

Estrogen withdrawal in chick oviduct. Selective loss of high abundance classes of polyadenylated messenger RNA

1977 • 84 citations

Multiple mechanisms of B cell immunoregulation in man after administration of in vivo corticosteroids.

1984 • 81 citations

A minimum of four human class II α-chain genes are encoded in the HLA region of chromosome 6

1983 • 77 citations

Comparison of the direct antiglobulin rosetting reaction with the mixed antiglobulin rosetting reaction for the detection of immunoglobulin on lymphocytes

1977 • 77 citations

Isolation of a cDNA clone for the human HLA-DR antigen alpha chain by using a synthetic oligonucleotide as a hybridization probe.

1982 • 63 citations

Anti-Ia Reactivity in Sera from Patients with Systemic Lupus Erythematosus

1982 • 59 citations

Decrease in HLA-DR-positive monocytes in patients with systemic lupus erythematosus (SLE).

1985 • 52 citations

Further evidence against random polyclonal antibody formation in mice with lupus-like graft-vs-host disease.

1984 • 48 citations

Identification of 5-methylcytosine in DNA fragments immobilized on nitrocellulose paper.

1980 • 47 citations

Epstein-Barr virus transformation of human pre-B cells.

1983 • 43 citations

Characterization of DNA methyltransferase from bovine thymus cells

1983 • 38 citations

Differentiation of Two Mouse Cell Lines Is Associated with Hypomethylation of Their Genomes

1984 • 35 citations

Nuclear DNA degradation in lymphocytes of patients with systemic lupus erythematosus.

1984 • 34 citations

Class II major histocompatibility antigens and the etiology of systemic lupus erythematosus

1983 • 31 citations

Cell surface properties of HLA antigens on Epstein-Barr virus-transformed cell lines.

1982 • 25 citations

The Interactions of Androgen Receptor with Poly(A)‐Containing RNA and Polyribonucleotides

1982 • 22 citations

Eukaryotic DNA methylase--properties and action on native DNA and chromatin.

1984 • 16 citations