The myelin basic protein-specific T cell repertoire in Lewis rats: T cell receptor diversity is influenced both by intrathymic milieu and by extrathymic peptide presentation

The rapid isolation of clonable antigen‐specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis

1981 • 917 citations

Limited diversity of γδ antigen receptor genes of thy-1+ dendritic epidermal cells

1988 • 522 citations

Lack of N Regions in Antigen Receptor Variable Region Genes of TdT-Deficient Lymphocytes

1993 • 474 citations

Mice Lacking TdT: Mature Animals with an Immature Lymphocyte Repertoire

1993 • 437 citations

Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences.

1990 • 414 citations

Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generation.

1990 • 396 citations

Myelin basic protein‐specific T lymphocyte lines from MS patients and healthy individuals

1990 • 332 citations

The adult T-cell receptor 5-chain is diverse and distinct from that of fetal thymocytes

1988 • 320 citations

Autoaggressive T lymphocyte lines recognizing the encephalitogenic region of myelin basic protein: in vitro selection from unprimed rat T lymphocyte populations.

1985 • 196 citations

T Cell Receptor Recognition of MHC Class II–Bound Peptide Flanking Residues Enhances Immunogenicity and Results in Altered TCR V Region Usage

1997 • 174 citations

Comparison of peptides bound to spleen and thymus class II.

1993 • 168 citations

T cell receptor β chain usage in myelin basic protein‐specific rat T lymphocytes

1989 • 162 citations

Thymic Selection by a Single MHC/Peptide Ligand Produces a Semidiverse Repertoire of CD4+ T Cells

1997 • 134 citations

Analysis of T cell receptor beta chains in Lewis rats with experimental allergic encephalomyelitis: conserved complementarity determining region 3.

1991 • 127 citations

Selection of a Broad Repertoire of CD4+ T Cells in H-2Ma0/0 Mice

1997 • 122 citations

Induction of TCR Gene Rearrangements in Uncommitted Stem Cells by a Subset of IL-7 Producing, MHC Class II–Expressing Thymic Stromal Cells

1997 • 119 citations

Junctional sequences of fetal T cell receptor beta chains have few N regions.

1991 • 117 citations

T Cells Can Be Activated by Peptides That Are Unrelated in Sequence to Their Selecting Peptide

1997 • 116 citations

Positive and Negative CD4+ Thymocyte Selection by a Single MHC Class II/Peptide Ligand Affected by Its Expression Level in the Thymus

1997 • 112 citations

The major myelin protein genes are expressed in the human thymus

1996 • 100 citations

Characterization of the immune response to a secondary encephalitogenic epitope of basic protein in Lewis rats. II. Biased T cell receptor V beta expression predominates in spinal cord infiltrating T cells.

1992 • 94 citations

T cell receptor sequences from encephalitogenic T cells in adult Lewis rats suggest an early ontogenic origin.

1992 • 70 citations

Complexity and sequence identification of 24 rat V beta genes.

1991 • 55 citations

Thymic expression of the golli-myelin basic protein gene in the SJL/J mouse

1995 • 48 citations

The peptide binding specificity of the MHC class II I-A molecule of the Lewis rat, RT1.B¹

1996 • 43 citations

Organization and nucleotide sequence of the rat T cell receptor beta-chain complex.

1991 • 41 citations

Half‐life of antigen/major histocompatibility complex class II complexes in vivo: intra‐ and interorgan variations

1993 • 35 citations

Definition of an extended MHC class II-peptide binding motif for the autoimmune disease-associated Lewis rat RT1.BL molecule

1997 • 34 citations

Identification of an N-terminally acetylated encephalitogenic epitope in myelin proteolipid apoprotein for the Lewis rat.

1994 • 33 citations

Differential expression of CLIP: MHC class II and conventional endogenous peptide: MHC class II complexes by thymic epithelial cells and peripheral antigen‐presenting cells

1996 • 31 citations

Heterogeneity of rat encephalitogenic T cells elicited by variants of the myelin basic protein (68–86) peptide

1995 • 23 citations

The myelin basic protein‐specific T cell repertoire in (transgenic) Lewis rat/SCID mouse chimeras: preferential Vβ8.2 T cell receptor usage depends on an intact Lewis thymic microenvironment

1996 • 18 citations