Zinc‐specific activation of a HeLa cell nuclear protein which interacts with a metal responsive element of the human metallothionein‐II_A gene

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP

1987 • 1,391 citations

DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

1979 • 1,339 citations

Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene

1984 • 955 citations

Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40

1987 • 762 citations

Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: Identification of an upstream control region

1981 • 646 citations

Regulation of Simian Virus 40 Transcription: Sensitive Analysis of the RNA Species Present Early in Infections by Virus or Viral DNA

1979 • 623 citations

α-Interferon-induced transcription of HLA and metallothionein genes containing homologous upstream sequences

1985 • 498 citations

Human metallothionein genes—primary structure of the metallothionein-II gene and a related processed gene

1982 • 464 citations

A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene.

1984 • 424 citations

Regulation, linkage, and sequence of mouse metallothionein I and II genes.

1984 • 335 citations

Structural and functional analysis of the human metallothionein-IA gene: Differential induction by metal ions and glucocorticoids

1984 • 331 citations

Structure of mouse metallothionein-I gene and its mRNA

1981 • 301 citations

A zinc-responsive factor interacts with a metal-regulated enhancer element (MRE) of the mouse metallothionein-I gene.

1988 • 297 citations

Induction of metallothionein and other mRNA species by carcinogens and tumor promoters in primary human skin fibroblasts.

1986 • 215 citations

Building a metal-responsive promoter with synthetic regulatory elements.

1985 • 199 citations

Activation of a heterologous promoter in response to dexamethasone and cadmium by metallothionein gene 5′-flanking DNA

1984 • 195 citations

Interleukin 1 regulates human metallothionein gene expression.

1985 • 185 citations

Fine Mapping of a Mouse Metallothionein Gene Metal Response Element

1989 • 185 citations

Constitutive and metal-inducible protein:DNA interactions at the mouse metallothionein I promoter examined by in vivo and in vitro footprinting.

1988 • 176 citations

Duplicated heavy metal control sequences of the mouse metallothionein-I gene.

1984 • 167 citations

The major late transcription factor binds to and activates the mouse metallothionein I promoter.

1987 • 160 citations

Dexamethasone Stimulation of Metallothionein Synthesis in HeLa Cell Cultures

1979 • 131 citations

Fine mapping of a mouse metallothionein gene metal response element.

1989 • 126 citations

Competition for cellular factors that activate metallothionein gene transcription

1984 • 107 citations

In Vivo Competition Between a Metallothionein Regulatory Element and the SV40 Enhancer

1986 • 106 citations

Regulation in Vitro of Metallothionein Gene Binding Factors

1987 • 101 citations

Metal-dependent binding of a factor in vivo to the metal-responsive elements of the metallothionein 1 gene promoter.

1987 • 87 citations

Metallothionein II

1987 • 83 citations

Hormonal Regulation of Liver Metallothionein Zinc: Independent and Synergistic Action of Glucagon and Glucocorticoids

1981 • 70 citations

Rat Metallothionein-1 Structural Gene and Three Pseudogenes, One of which Contains 5′-Regulatory Sequences

1986 • 68 citations

Zinc dependent binding of a liver nuclear factor to metal response element MRE-a of the mouse metallothionein-l gene and variant sequences

1990 • 65 citations

Transcription factor MBF-I interacts with metal regulatory elements of higher eucaryotic metallothionein genes.

1989 • 59 citations

Regulation of the rat metallothionein-I gene by sodium butyrate

1986 • 58 citations

Detection of a nuclear protein that interacts with a metal regulatory element of the mouse metallothionein 1 gene

1988 • 53 citations

Rat metallothionein-1 structural gene and three pseudogenes, one of which contains 5'-regulatory sequences.

1986 • 52 citations

The sheep metallothionein gene family

1988 • 50 citations

Structure and regulation of the sheep metallothionein‐Ia gene

1986 • 40 citations

A nuclear factor requires Zn24 to bind a regulatory MRE element of the mouse gene encoding metallothionein-1

1991 • 35 citations

Cd2+-induced synthesis of metallothionein in HeLa cells

1985 • 33 citations

Evidence for more than two metallothionein isoforms in primates.

1985 • 29 citations

Induction of metallothionein synthesis in cultured cells derived from rabbit kidney

1985 • 22 citations

A nuclear factor that interacts with metal responsive elements of a human metallothionein gene

1991 • 14 citations