Activation of Drosophila Toll During Fungal Infection by a Blood Serine Protease

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

1996 • 3,854 citations

Phylogenetic Perspectives in Innate Immunity

1999 • 2,478 citations

The Toll gene of drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein

1988 • 1,077 citations

Drosophila host defense: Differential induction of antimicrobial peptide genes after infection by various classes of microorganisms

1997 • 969 citations

Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein

2001 • 759 citations

Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli

2002 • 698 citations

The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein

2002 • 658 citations

A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense.

1995 • 590 citations

Requirement for a Peptidoglycan Recognition Protein (PGRP) in Relish Activation and Antibacterial Immune Responses in Drosophila

2002 • 576 citations

A family of peptidoglycan recognition proteins in the fruit flyDrosophila melanogaster

2000 • 525 citations

Constitutive Activation of Toll-Mediated Antifungal Defense in Serpin-Deficient Drosophila

1999 • 429 citations

Drosophila Immune Deficiency (IMD) Is a Death Domain Protein that Activates Antibacterial Defense and Can Promote Apoptosis

2001 • 421 citations

The spätzle gene encodes a component of the extracellular signaling pathway establishing the dorsal-ventral pattern of the Drosophila embryo

1994 • 321 citations

Evolution of enzyme cascades from embryonic development to blood coagulation

2002 • 311 citations

The role of hemolymph coagulation in innate immunity

1996 • 271 citations

Role of Drosophila IKKγ in a Toll-independent antibacterial immune response

2000 • 266 citations

Prophenoloxidase-activating Enzyme of the Silkworm, Bombyx mori

1999 • 229 citations

Signal transduction by a protease cascade

1999 • 119 citations

The necrotic Gene in Drosophila Corresponds to One of a Cluster of Three Serpin Transcripts Mapping at 43A1.2

2000 • 75 citations

The structural puzzle of how serpin serine proteinase inhibitors work

1996 • 66 citations

Mutational analysis of the Drosophila snake protease: an essential role for domains within the proenzyme polypeptide chain.

1994 • 45 citations

Where Cell Biology and Developmental Biology Meet

2001 • 12 citations