Role of adenosine A1 receptor in the perifornical–lateral hypothalamic area in sleep–wake regulation in rats

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

AChE-stained horizontal sections of the rat brain in stereotaxic coordinates

1980 • 4,422 citations

Narcolepsy in orexin Knockout Mice

1999 • 3,014 citations

The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene

1999 • 2,583 citations

International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors.

2001 • 2,470 citations

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

2000 • 2,065 citations

Reduced Number of Hypocretin Neurons in Human Narcolepsy

2000 • 2,004 citations

The Role and Regulation of Adenosine in the Central Nervous System

2001 • 1,595 citations

Genetic Ablation of Orexin Neurons in Mice Results in Narcolepsy, Hypophagia, and Obesity

2001 • 1,387 citations

The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness

2007 • 1,177 citations

Discharge of Identified Orexin/Hypocretin Neurons across the Sleep-Waking Cycle

2005 • 840 citations

Behavioral Correlates of Activity in Identified Hypocretin/Orexin Neurons

2005 • 830 citations

Astrocytic Modulation of Sleep Homeostasis and Cognitive Consequences of Sleep Loss

2009 • 815 citations

Restoration of brain energy metabolism as the function of sleep

1995 • 811 citations

Fos Expression in Orexin Neurons Varies with Behavioral State

2001 • 647 citations

From waking to sleeping: neuronal and chemical substrates

2005 • 568 citations

Adenosine and sleep–wake regulation

2004 • 548 citations

Hypocretin-1 Modulates Rapid Eye Movement Sleep through Activation of Locus Coeruleus Neurons

2000 • 506 citations

Adenosine receptors in the nervous system: pathophysiological implications

2002 • 502 citations

Neurobiology of REM and NREM sleep

2007 • 500 citations

Melanin-concentrating hormone neurons discharge in a reciprocal manner to orexin neurons across the sleep–wake cycle

2009 • 420 citations

A role of melanin-concentrating hormone producing neurons in the central regulation of paradoxical sleep.

2003 • 416 citations

Neurobiological mechanisms for the regulation of mammalian sleep–wake behavior: Reinterpretation of historical evidence and inclusion of contemporary cellular and molecular evidence

2007 • 289 citations

Hypocretin-2-Saporin Lesions of the Lateral Hypothalamus Produce Narcoleptic-Like Sleep Behavior in the Rat

2001 • 273 citations

Hypocretin (OREXIN): Role in Normal Behavior and Neuropathology

2004 • 254 citations

Adenosine analogs and sleep in rats.

1984 • 239 citations

Stimulation of A1 adenosine receptors mimics the electroencephalographic effects of sleep deprivation

1995 • 224 citations

Neuronal activity of orexin and non-orexin waking-active neurons during wake–sleep states in the mouse

2008 • 223 citations

Adenosine and Sleep Homeostasis in the Basal Forebrain

2006 • 205 citations

Orexin and MCH neurons express c‐Fos differently after sleep deprivation vs. recovery and bear different adrenergic receptors

2005 • 195 citations

Caffeine Reduces Low-Frequency Delta Activity in the Human Sleep EEG

1995 • 191 citations

Adenosine Inhibits Activity of Hypocretin/Orexin Neurons by the A1 Receptor in the Lateral Hypothalamus: A Possible Sleep-Promoting Effect

2006 • 186 citations

The energy hypothesis of sleep revisited

2008 • 185 citations

Sleep‐waking discharge patterns of neurons recorded in the rat perifornical lateral hypothalamic area

2002 • 184 citations

Sleep function(s) and cerebral metabolism

1995 • 177 citations

Hypothalamic regulation of sleep and arousal

2003 • 173 citations

Adenosinergic modulation of rat basal forebrain neurons during sleep and waking: neuronal recording with microdialysis

1999 • 169 citations

A₁Receptor and Adenosinergic Homeostatic Regulation of Sleep-Wakefulness: Effects of Antisense to the A₁Receptor in the Cholinergic Basal Forebrain

2003 • 167 citations

Fos immunoreactivity in hypocretin-synthesizing and hypocretin-1 receptor-expressing neurons: effects of diurnal and nocturnal spontaneous waking, stress and hypocretin-1 administration

2003 • 143 citations

Adenosine in the tuberomammillary nucleus inhibits the histaminergic system via A ₁ receptors and promotes non-rapid eye movement sleep

2008 • 139 citations

Microdialysis perfusion of orexin-A in the basal forebrain increases wakefulness in freely behaving rats.

2001 • 134 citations

Effects of lateral preoptic area application of orexin-A on sleep–wakefulness

2000 • 126 citations

GABA‐mediated control of hypocretin‐ but not melanin‐concentrating hormone‐immunoreactive neurones during sleep in rats

2004 • 114 citations

Adenosine and the homeostatic control of sleep: Effects of A1 receptor blockade in the perifornical lateral hypothalamus on sleep–wakefulness

2008 • 112 citations

State-dependent activity of neurons in the perifornical hypothalamic area during sleep and waking

2003 • 101 citations

Adenosinergic inhibition of basal forebrain wakefulness-active neurons: a simultaneous unit recording and microdialysis study in freely behaving cats

2003 • 97 citations

Effects on sleep of microdialysis of adenosine A₁and A_2areceptor analogs into the lateral preoptic area of rats

2005 • 97 citations

Sleep deprivation upregulates A1 adenosine receptors in the rat basal forebrain

2007 • 81 citations

Orexin neurons of the hypothalamus express adenosine A1 receptors

2002 • 67 citations

Different Neuronal Phenotypes in the Lateral Hypothalamus and Their Role in Sleep and Wakefulness

2004 • 66 citations

Microdialysis: A system for localized drug delivery into the brain

1989 • 57 citations

Differential acute influence of medial and lateral preoptic areas on sleep-wakefulness in freely moving rats

1990 • 57 citations

Glutamic acid stimulation of the perifornical-lateral hypothalamic area promotes arousal and inhibits non-REM/REM sleep

2008 • 46 citations

Immunohistochemical localization of caffeine-induced c-Fos protein expression in the rat brain

1998 • 41 citations

Effects of serotonin on perifornical‐lateral hypothalamic area neurons in rat

2007 • 33 citations

Effects of hypocretin (orexin) neuronal loss on sleep and extracellular adenosine levels in the rat basal forebrain

2008 • 29 citations