A₁Receptor and Adenosinergic Homeostatic Regulation of Sleep-Wakefulness: Effects of Antisense to the A₁Receptor in the Cholinergic Basal Forebrain

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

AChE-stained horizontal sections of the rat brain in stereotaxic coordinates

1980 • 4,422 citations

Adenosine: A Mediator of the Sleep-Inducing Effects of Prolonged Wakefulness

1997 • 1,198 citations

Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration

1997 • 994 citations

Specific regulation of gene expression by antisense, sense and antigene nucleic acids

1990 • 769 citations

Characterization of oligonucleotide transport into living cells.

1989 • 739 citations

Mechanism of oligonucleotide uptake by cells: involvement of specific receptors?

1989 • 510 citations

Brain site-specificity of extracellular adenosine concentration changes during sleep deprivation and spontaneous sleep: an in vivo microdialysis study

2000 • 451 citations

Role of RNase H in hybrid-arrested translation by antisense oligonucleotides.

1988 • 445 citations

Oligodeoxynucleotides as inhibitors of gene expression: a review.

1988 • 419 citations

Sleep deprivation in rats: effects on EEG power spectra, vigilance states, and cortical temperature

1991 • 403 citations

Adenosinergic modulation of basal forebrain and preoptic/anterior hypothalamic neuronal activity in the control of behavioral state

2000 • 358 citations

Adenosine Inhibition of Mesopontine Cholinergic Neurons: Implications for EEG Arousal

1994 • 338 citations

Magnocellular Nuclei of the Basal Forebrain: Substrates of Sleep and Arousal Regulation

1995 • 272 citations

Antisense oligonucleotide strategies in neuropharmacology

1994 • 265 citations

A Hippocampal NR2B Deficit Can Mimic Age-Related Changes in Long-Term Potentiation and Spatial Learning in the Fischer 344 Rat

2002 • 251 citations

Adenosine analogs and sleep in rats.

1984 • 239 citations

Role of adenosine in behavioral state modulation: a microdialysis study in the freely moving cat

1997 • 212 citations

Increased hypothalamic expression of prolactin in lactation: involvement in behavioural and neuroendocrine stress responses

2002 • 212 citations

Specific Gap Junctions Enhance the Neuronal Vulnerability to Brain Traumatic Injury

2002 • 211 citations

Modification of antisense phosphodiester oligodeoxynucleotides by a 5' cholesteryl moiety increases cellular association and improves efficacy.

1993 • 203 citations

Behavioral State Control through Differential Serotonergic Inhibition in the Mesopontine Cholinergic Nuclei: A Simultaneous Unit Recording and Microdialysis Study

1998 • 193 citations

The effect of 3-h and 6-h sleep deprivation on sleep and EEG spectra of the rat

1990 • 185 citations

Dynamics of the internalization of phosphodiester oligodeoxynucleotides in HL60 cells

1993 • 172 citations

The experimental use of antisense oligonucleotides: a guide for the perplexed

2001 • 172 citations

Adenosinergic modulation of rat basal forebrain neurons during sleep and waking: neuronal recording with microdialysis

1999 • 169 citations

Microdialysis perfusion of orexin-A in the basal forebrain increases wakefulness in freely behaving rats.

2001 • 134 citations

Temporal progression of kainic acid induced neuronal and myelin degeneration in the rat forebrain

2000 • 130 citations

Characterizing cortical neuron injury with fluoro-jade labeling after a neurotoxic regimen of methamphetamine

1998 • 114 citations

The Critical Role of Basement Membrane-Independent Laminin γ1 Chain during Axon Regeneration in the CNS

2002 • 104 citations

Adenosinergic inhibition of basal forebrain wakefulness-active neurons: a simultaneous unit recording and microdialysis study in freely behaving cats

2003 • 97 citations

Adenosine, prolonged wakefulness, and A1-activated NF-κB DNA binding in the basal forebrain of the rat

2001 • 94 citations

The application of antisense oligonucleotide technology to the brain: Some pitfalls

1994 • 91 citations

Opposite changes in adenosine A1 and A2A receptor mRNA in the rat following sleep deprivation

2001 • 80 citations

Two problems in antisense biotechnology: in vitro delivery and the design of antisense experiments

1999 • 78 citations

Orexin neurons of the hypothalamus express adenosine A1 receptors

2002 • 67 citations

Antisense technology: biological utility and practical considerations

1993 • 62 citations

Microdialysis: A system for localized drug delivery into the brain

1989 • 57 citations

REM sleep enhancement and behavioral cataplexy following orexin (hypocretin)-II receptor antisense perfusion in the pontine reticular formation.

1999 • 55 citations

The neural basis of consciousness across the sleep-waking cycle.

1998 • 53 citations

Adenosine Induces Inositol 1,4,5-Trisphosphate Receptor-Mediated Mobilization of Intracellular Calcium Stores in Basal Forebrain Cholinergic Neurons

2002 • 52 citations

Antisense oligodeoxynucleotides as specific tools for studying neuroendocrine and behavioral functions: Some prospects and problems

1997 • 30 citations

Phasic but not tonic REM-selective discharge of periaqueductal gray neurons in freely behaving animals: relevance to postulates of GABAergic inhibition of monoaminergic neurons

2002 • 28 citations

Entorhinal cortex lesion studied with the novel dye Fluoro-Jade

2000 • 28 citations

Antisense oligodeoxynucleotide‐induced suppression of basal forebrain NMDA‐NR1 subunits selectively impairs visual attentional performance in rats

2001 • 23 citations

Intrastriatal adenosine A1 receptor antisense oligodeoxynucleotide blocks ethanol-induced motor incoordination

1997 • 19 citations

The experimental use of antisense oligonucleotides: a guide for the perplexed

2001 • 18 citations

Use of Antisense Oligodeoxynucleotides to Study the Physiological Functions of Neuropeptide Y

2000 • 15 citations

In vivo antisense inhibition of prodynorphin expression in rat striatum: dose-dependence and sequence specificity

1995 • 13 citations

Adenosine A1 receptor antisense infused in striatum of rats: Actions on alcohol-induced locomotor impairment, blood alcohol, and body temperature

1997 • 10 citations

Effect of rapid eye movement sleep deprivation on 5′-nucleotidase activity in the rat brain

1996 • 8 citations

Autoradiographic evidence that intrastriatal administration of adenosine A1 receptor antisense oligodeoxynucleotide decreases adenosine A1 receptors in the rat striatum and cortex

1999 • 4 citations