Role of nitric oxide and peroxynitrite in the cytokine-induced sustained myocardial dysfunction in dogs in vivo.

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

1996 • 5,498 citations

Measurement of Cutaneous Inflammation: Estimation of Neutrophil Content with an Enzyme Marker

1982 • 3,566 citations

The stunned myocardium: prolonged, postischemic ventricular dysfunction.

1982 • 2,825 citations

Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis.

1981 • 2,777 citations

Elevated Circulating Levels of Tumor Necrosis Factor in Severe Chronic Heart Failure

1990 • 2,566 citations

The Reaction of no With Superoxide

1993 • 2,133 citations

Negative Inotropic Effects of Cytokines on the Heart Mediated by Nitric Oxide

1992 • 1,635 citations

Peroxynitrite formation from macrophage-derived nitric oxide

1992 • 1,118 citations

Tumor Necrosis Factor-α and Tumor Necrosis Factor Receptors in the Failing Human Heart

1996 • 993 citations

Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition.

1988 • 990 citations

Serum Cytokine Levels in Human Septic Shock

1993 • 882 citations

Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock

1991 • 873 citations

Selective inhibition of the inducible nitric oxide synthase by aminoguanidine

1993 • 734 citations

The Pathogenesis of Atherosclerosis: Atherogenesis and Inflammation

1989 • 701 citations

Control of cardiac muscle cell function by an endogenous nitric oxide signaling system.

1993 • 656 citations

Inhibition of the iron-catalysed formation of hydroxyl radicals from superoxide and of lipid peroxidation by desferrioxamine

1979 • 637 citations

Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide.

1993 • 623 citations

Induction and potential biological relevance of a Ca²⁺‐independent nitric oxide synthase in the myocardium

1992 • 623 citations

Aconitase is readily inactivated by peroxynitrite, but not by its precursor, nitric oxide.

1994 • 596 citations

Increased circulating cytokines in patients with myocarditis and cardiomyopathy.

1994 • 525 citations

Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium.

1993 • 457 citations

Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. Characterization and regulation of iNOS expression and detection of iNOS activity in single cardiac myocytes in vitro.

1994 • 436 citations

Nitric oxide attenuates cardiac myocyte contraction

1993 • 405 citations

Nitric oxide production within cardiac myocytes reduces their contractility in endotoxemia

1992 • 327 citations

Enhancement of recovery of myocardial function by oxygen free-radical scavengers after reversible regional ischemia.

1985 • 324 citations

Immune mechanisms in atherosclerosis.

1989 • 247 citations

Granulocytes cause reperfusion ventricular dysfunction after 15-minute ischemia in the dog.

1987 • 231 citations

A Rapid Method for Acid Hydrolysis of Protein with a Mixture of Trifluoroacetic Acid and Hydrochloric Acid

1982 • 220 citations

Induction of myocardial nitric oxide synthase by cardiac allograft rejection.

1994 • 212 citations

Complement C5a, TGF-β1, and MCP-1, in Sequence, Induce Migration of Monocytes Into Ischemic Canine Myocardium Within the First One to Five Hours After Reperfusion

1997 • 211 citations

Cytokine signaling during myocardial infarction: sequential appearance of IL-1 beta and IL-6

1995 • 174 citations

Persistent Expression of Cytokine in the Chronic Stage of Viral Myocarditis in Mice

1996 • 171 citations

Interaction of neutrophils with vascular smooth muscle: identification of a neutrophil-derived relaxing factor.

1988 • 160 citations

Inhibition of nitric oxide formation by guanidines

1993 • 154 citations

Induction of nitric oxide synthase gene by interleukin-1 beta in cultured rat cardiocytes.

1994 • 154 citations

Role of nitric oxide in antagonistic effects of transforming growth factor-beta and interleukin-1 beta on the beating rate of cultured cardiac myocytes.

1992 • 150 citations

Peroxynitrite-induced cardiac myocyte injury

1996 • 111 citations

Interleukin-1 modulates myocardial contraction via dexamethasone sensitive production of nitric oxide

1993 • 108 citations

Myocardial calcium-independent nitric oxide synthase activity is present in dilated cardiomyopathy, myocarditis, and postpartum cardiomyopathy but not in ischaemic or valvar heart disease.

1995 • 98 citations

Nitric oxide synthesis in cardiac myocytes and fibroblasts by inflammatory cytokines

1995 • 86 citations

Neutrophil oxygen radical generation. Synergistic responses to tumor necrosis factor and mono/polyunsaturated fatty acids.

1996 • 74 citations

Monocyte-related cytokines in acute myocardial infarction

1995 • 67 citations

Nitric oxide synthase inhibition partially prevents decreased LV contractility during endotoxemia

1996 • 52 citations

Identification of 3-nitro-l-tyrosine, a product of nitric oxide and superoxide, as an indicator of oxidative stress in the human brain

1996 • 45 citations

Role of superoxide anion in the pathogenesis of cytokine-induced myocardial dysfunction in dogs in vivo

1999 • 45 citations

Nitric oxide synthesis in cardiac myocytes and fibroblasts by inflammatory cytokines

1995 • 44 citations

Mechanisms of Interleukin-1β Regulation of Nitric Oxide Synthase in Cardiac Myocytes

1996 • 43 citations

Cardiac inducible nitric oxide synthase negatively modulates myocardial function in cultured rat myocytes

1997 • 38 citations

Role of P-selectin in the early stage of the Arthus reaction

1996 • 24 citations