Enzyme in der organischen Synthese

Methods of Enzymatic Analysis

1974 • 6,512 citations

Methods of enzymatic analysis

1964 • 5,230 citations

Quantitative analyses of biochemical kinetic resolutions of enantiomers

1982 • 2,569 citations

The first practical method for asymmetric epoxidation

1980 • 2,522 citations

Double Asymmetric Synthesis and a New Strategy for Stereochemical Control in Organic Synthesis

1985 • 1,078 citations

Enzymatic Catalysis in Organic Media at 100°C

1984 • 1,040 citations

Experimental and Theoretical Aspects of Protein Folding

1975 • 965 citations

Advances in Selective Chemical Syntheses of Complex Oligosaccharides

1982 • 952 citations

The Formation of 2-Keto-3-deoxyheptonic Acid in Extracts of Escherichia coli B

1959 • 847 citations

Transcription and Translation — A Practical Approach

1985 • 811 citations

Industrial enzymology

1983 • 725 citations

Asymmetric hydrogenation

1983 • 707 citations

Primary Structure of Glycoprotein Glycans Basis for the Molecular Biology of Glycoproteins

1980 • 560 citations

The Enzymatic Synthesis of S-Adenosyl-l-homocysteine from Adenosine and Homocysteine

1959 • 546 citations

Conversion of a protein to a homogeneous asymmetric hydrogenation catalyst by site-specific modification with a diphosphinerhodium(I) moiety

1978 • 528 citations

Stereocontrol in the synthesis of acyclic systems: applications to natural product synthesis

1980 • 497 citations

Enzymatic reaction mechanisms

1980 • 469 citations

Stabilization of Enzymes against Thermal Inactivation

1983 • 458 citations

Immobilized Enzymes and Cells as Practical Catalysts

1983 • 452 citations

Mechanism and Stereoselectivity of Asymmetric Hydrogenation

1982 • 449 citations

Rate constants and equilibrium constants for thiol-disulfide interchange reactions involving oxidized glutathione

1980 • 400 citations

Enzymes Hosted in Reverse Micelles in Hydrocarbon Solution

1985 • 383 citations

Peroxidase-Catalyzed Halogenation

1976 • 376 citations

Autoxidation of methyl linoleate. Separation and analysis of isomeric mixtures of methyl linoleate hydroperoxides and methyl hydroxylinoleates

1977 • 356 citations

Doppelte Stereodifferenzierung und eine neue Strategie zur Stereokontrolle in der Organischen Synthese

1985 • 327 citations

Enzymes in organic synthesis-29

1984 • 324 citations

Artificial Enzymes

1982 • 318 citations

Selectivity: A Key to Synthetic Efficiency

1983 • 315 citations

Disulfide Bond Engineered into T4 Lysozyme: Stabilization of the Protein Toward Thermal Inactivation

1984 • 311 citations

Lignin synthesis: The generation of hydrogen peroxide and superoxide by horseradish peroxidase and its stimulation by manganese (II) and phenols

1978 • 290 citations

The Sialic Acids

1960 • 287 citations

Stereocontrolled synthesis of (+)-negamycin from an acyclic homoallylamine by 1,3-asymmetric induction

1982 • 278 citations

Basic Principles of Protease‐Catalyzed Peptide Bond Formation

1985 • 271 citations

Preparative production of optically active esters and alcohols using esterase-catalyzed stereospecific transesterification in organic media

1984 • 269 citations

Enzyme immobilization by condensation copolymerization into crosslinked polyacrylamide gels

1980 • 261 citations

Enzyme-catalyzed organic synthesis: NAD(P)H cofactor regeneration by using glucose-6-phosphate and the glucose-5-phosphate dehydrogenase from Leuconostoc mesenteroides

1981 • 260 citations

The Biochemistry of Adenosylmethionine

1978 • 257 citations

ENZYMATIC SYNTHESIS AND BREAKDOWN OF DESOXYRIBOSE PHOSPHATE

1952 • 255 citations

Binding of substrate in a ternary complex of horse liver alcohol dehydrogenase.

1982 • 255 citations

Enzymatic ω-Oxidation

1966 • 246 citations

Synthesis of peptide bonds by proteinases. Addition of organic cosolvents shifts peptide bond equilibriums toward synthesis

1978 • 245 citations

Applications of biochemical systems in organic chemistry

1976 • 243 citations

Microbial Asymmetric Catalysis—Enantioselective Reduction of Ketones [New Synthetic Methods (45)]

1984 • 237 citations

Methods for the analysis and preparation of adenosylmethionine and adenosylhomocysteine

1966 • 234 citations

Chiral Compounds Synthesized by Biocatalytic Reductions [New Synthetic Methods (51)]

1985 • 231 citations

S-Adenosylmethionine synthetase from Escherichia coli.

1980 • 230 citations

Lipase-catalyzed hydrolysis as a route to esters of chiral epoxy alcohols

1984 • 227 citations

[15] Phospholipase A2 (phosphatide acylhydrolase, EC 3.1.1.4) from porcine pancreas

1974 • 226 citations

Enzyme-catalyzed synthesis of N-acetyllactosamine with in situ regeneration of uridine 5'-diphosphate glucose and uridine 5'-diphosphate galactose

1982 • 215 citations

MICROBIOLOGICAL OXYGENATION OF STEROIDS AT CARBON 11

1952 • 202 citations

A Study of Stereoselective Hydrolysis of Symmetrical Diesters with Pig Liver Esterase

1983 • 201 citations

Glycoproteins: research booming on long-ignored, ubiquitous compounds

1981 • 201 citations

Chemical Mutation of Enzyme Active Sites

1984 • 199 citations

Colloidal Solution of Water in Organic Solvents: a Microheterogeneous Medium for Enzymatic Reactions

1982 • 197 citations

Enzymes in organic synthesis. 24. Preparations of enantiomerically pure chiral lactones via stereospecific horse liver alcohol dehydrogenase catalyzed oxidations of monocyclic meso diols

1982 • 196 citations

Chemical and enzymic syntheses of 5-HPETE, a key biological precursor of slow-reacting substance of anaphylaxis (SRS), and 5-HETE

1980 • 196 citations

Bifunctional chiral synthons via biochemical methods. III. Optical purity enhancement in enzymic asymmetric catalysis

1984 • 195 citations

Enantioselective synthesis of the carbocyclic nucleosides (-)-aristeromycin and (-)-neplanocin A by a chemicoenzymatic approach

1983 • 193 citations

Enzyme-catalyzed organic synthesis: NADH regeneration by using formate dehydrogenase

1980 • 190 citations

Total Synthesis of the L-Hexoses

1983 • 190 citations

Biochemistry of S-Adenosylmethionine and Related Compounds

1982 • 185 citations

Enzymatic synthesis in biphasic aqueous-organic systems. I. Chemical equilibrium shift

1981 • 182 citations

Immobilized enzymes — research and development

1979 • 180 citations

Immobilized Cells and Organelles

2019 • 175 citations

Chloroperoxidase halogenation reactions. Chemical versus enzymic halogenating intermediates.

1982 • 175 citations

Chemical and enzymatic synthesis of gene fragments

1983 • 174 citations

Oxidation of Hydrocarbons by Methane Monooxygenases from a Variety of Microbes

1980 • 173 citations

Rates of thiol-disulfide interchange reactions involving proteins and kinetic measurements of thiol pKa values

1980 • 171 citations

Structure-stability relationships in proteins: new approaches to stabilizing enzymes

1984 • 169 citations

Biocatalysis in water-organic solvent two-phase systems

1984 • 168 citations

Enzymic synthesis of hydrocarbon-soluble peptides with reverse micelles

1984 • 167 citations

New findings in methane-utilizing bacteria highlight their importance in the biosphere and their commercial potential

1980 • 165 citations

Topics in enzyme and fermentation biotechnology

1988 • 164 citations

Erythro-selective aldol reaction via tris(dialkylamino)sulfonium enolates

1981 • 159 citations

Synthese von optisch aktiven, natürlichen Carotinoiden und strukturell verwandten Naturprodukten. I. Synthese der chiralen Schlüsselverbindung (4R, 6R)‐4‐Hydroxy‐2,2,6‐trimethylcyclohexanon

1976 • 157 citations

Lipolytic Enzymes

1974 • 155 citations

Ester synthesis catalyzed by polyethylene glycol-modified lipase in benzene

1984 • 152 citations

Semi-synthesis of human insulin by trypsin-catalysed replacement of Ala-B30 by Thr in porcine insulin

1979 • 152 citations

Sulfation of drugs and related compounds

1983 • 152 citations

Acyclic Stereocontrol Through the Aldol Condensation

1981 • 151 citations

Synthesis of glycerophospholipids

1980 • 150 citations

Biological and Biochemical Aspects of Microbial Growth on C1 Compounds

1979 • 149 citations

Two‐liquid‐phase biocatalytic reactions

1982 • 148 citations

An die Mitglieder des Vereins deutscher Chemiker

1911 • 145 citations

Enzyme-assisted semisynthesis of human insulin

1979 • 143 citations

Preparation of (R)- and (S)-mevalonic acids

1975 • 141 citations

Enzyme catalysed reactions in water - Organic solvent two-phase systems

1981 • 135 citations

Synthesis of sugars by aldolase-catalyzed condensation reactions

1983 • 135 citations

[53] Preparation of phospholipids and their analogs by phospholipase D

1981 • 134 citations

Role of the arene oxide-oxepin system in the metabolism of aromatic substrates. IV. Stereochemical considerations of dihydrodiol formation and dehyrogenation

1970 • 132 citations

Modifizierte Ionenaustauscher als spezifische Adsorbentien

1953 • 130 citations

Industrial‐scale application of enzymes to the fats and oil industry

1984 • 129 citations

Synthesis of phosphoenolypyruvate and its use in ATP cofactor regeneration

1982 • 129 citations

A chemical modification to make horseradish peroxidase soluble and active in benzene

1984 • 128 citations

α-Chymotrypsin as the catalyst for peptide synthesis

1977 • 127 citations

Synthesis of an aspartame precursor by immobilized thermolysin in an organic solvent

1981 • 127 citations

Continuous production ofL-malic acid by immobilizedBrevibacterium ammoniagenes cells

1976 • 125 citations

Continuous synthesis of glycerides by lipase in a microporous membrane bioreactor

1984 • 124 citations

Enzyme-catalyzed organic synthesis: electrochemical regeneration of NAD(P)H from NAD(P) using methyl viologen and flavoenzymes

1981 • 123 citations

Phospholipids as Functional Constituents of Biomembranes

1984 • 120 citations

Synthesis of (S)- and (R)-4[(methoxycarbonyl)methyl]-2-azetidinone by chemicoenzymic approach

1981 • 119 citations

Sulfation of Drugs and Related Compounds

2020 • 118 citations

THE MECHANISM OF “ACTIVE SULFATE” FORMATION¹

1956 • 115 citations

A new enzymatic method of acrylamide production.

1982 • 114 citations

Purification and characterization of 3-deoxy-D-manno-octulosonate 8-phosphate synthetase from Escherichia coli

1980 • 113 citations

[51] Production of l-amino acids by aminoacylase adsorbed on DEAE-sephadex

1976 • 110 citations

The Metabolism of l-Fucose

1962 • 109 citations

Totalsynthese von natürlichem α‐Tocopherol. 1. Mitteilung. Herstellung bifunktioneller, optisch aktiver Synthesebausteine für die Seitenkette mit Hilfe mikrobiologischer Umwandlungen

1979 • 107 citations

Cyclohexanone oxygenase: stereochemistry, enantioselectivity, and regioselectivity of an enzyme-catalyzed Baeyer-Villiger reaction

1983 • 104 citations

Bioconversion of sitosterol to useful steroidal intermediates by mutants of Mycobacterium fortuitum

1978 • 101 citations

Production and Utilization of Amino Acids

1978 • 100 citations

CHEMICAL DERIVATIVES OF CHYMOTRYPSINOGEN

1956 • 99 citations

The Absolute Configuration of Dihydroxyacetone Phosphate Tritiated by Aldolase Reaction¹

1958 • 98 citations

A new cubic-space section model for predicting the specificity of horse liver alcohol dehydrogenase-catalyzed oxidoreductions

1982 • 97 citations

Analysis of Enzyme Structure and Activity by Protein Engineering

1984 • 97 citations

Creation of novel chiral synthons with enzymes and applications to natural product synthesis. 15. Efficient introduction of chiral centers into cyclohexane ring

1984 • 96 citations

Synthesis with immobilized enzyme of the most important sialic acid.

1984 • 96 citations

Biosynthesis of chondroitin sulfate. Sulfation of the polysaccharide chain

1973 • 95 citations

Potential applications of an alcohol-aldehyde/ketone oxidoreductase from thermophilic bacteria

1981 • 94 citations

Synthesis of 1'-deoxy-1'-fluorosucrose via sucrose synthetase mediated coupling of 1-deoxy-1-fluorofructose with uridine diphosphate glucose

1984 • 93 citations

Preparation of Pharmaceutical Compounds by Immobilized Enzymes and Cells

1976 • 93 citations

A Pure Enzyme Catalyzing Penicillin Biosynthesis

1984 • 92 citations

Chemical and enzymatic syntheses of 6-deoxyhexoses. Conversion to 2,5-dimethyl-4-hydroxy-2,3-dihydrofuran-3-one (Furaneol) and analogs

1983 • 92 citations

Continuous production of <scp>L</scp>‐aspartic acid by immobilized aspartase

1973 • 90 citations

The Stoichiometry of the Conversion of Cholesterol and Hydroxycholesterols to Pregnenolone (3β-Hydroxypregn-5-en-20-one) Catalysed by Adrenal Cytochrome P -450

1974 • 90 citations

Continuous Synthesis of Optically Activa α-Hydroxynitriles

1966 • 89 citations

Chemical oxidations with microorganisms

1972 • 89 citations

[41] Purification of mammalian glycosyltransferases

1982 • 89 citations

Preparative hydroxylation of aromatic compounds catalyzed by peroxidase

1981 • 88 citations

Enzymatic Syntheses of Chiral Building Blocks from Prochiral meso‐Substrates: Preparation of Methyl(hydrogen)‐1,2‐cycloalkanedicarboxylates

1984 • 87 citations

Enzymatic Oxidation of Alkyl Sulfides by Cytochrome P-450 and Hydroxyl Radical

1981 • 86 citations

Peptide synthesis in aqueous–organic solvent mixtures with α‐chymotrypsin immobilized to tresyl chloride‐activated agarose

1984 • 86 citations

Topics in enzyme and fermentation biotechnology 1

1977 • 83 citations

Stereoselective epoxidation of octadiene catalyzed by an enzyme system of Pseudomonas oleovorans

1974 • 82 citations

A Kinetic Study of Nucleotide Interactions with Pyruvate Kinase^*

1965 • 81 citations

Mechanistic studies on non-heme iron monooxygenase catalysis: epoxidation, aldehyde formation and demethylation by the .omega.-hydroxylation system of Pseudomonas oleovorans

1984 • 80 citations

Novel haloperoxidase substrates. Alkynes and cyclopropanes.

1983 • 80 citations

Use of enzymes in peptide synthesis

1982 • 80 citations

Oxidoreductase Enzymes in Biotechnology: Current Status and Future Potential

1983 • 79 citations

A convenient synthesis of disodium acetyl phosphate for use in in situ ATP cofactor regeneration

1983 • 78 citations

Enantioselective and Enantioconvergent Syntheses of Building Blocks for the Total Synthesis of Cyclopentanoid Natural Products

1984 • 77 citations

Laboratory-scale enzymic/chemical syntheses of D- and L-.beta.-chlorolactic acid and D- and L-potassium glycidate

1982 • 76 citations

Mikrobielle asymmetrische Katalyse — enantioselektive Reduktion von Ketonen

1984 • 75 citations

Deoxyribose Aldolase from Lactobacillus plantarum

1960 • 75 citations

Total synthesis of carbohydrates. 3. Efficient enantioselective syntheses of 2,6-dideoxyhexoses

1983 • 75 citations

Practical synthesis of 5-phospho-D-ribosyl .alpha.-1-pyrophosphate (PRPP): enzymatic routes from ribose 5-phosphate or ribose

1983 • 74 citations

Peroxide oxidation of primary alcohols to aldehydes by chloroperoxidase catalysis

1983 • 74 citations

Phospholipide als funktionelle Bausteine biologischer Membranen

1984 • 73 citations

Biocatalysis in natural products chemistry

1984 • 72 citations

L-Rhamnulose-1-phosphate aldolase from Escherichia coli. Crystallization and properties

1969 • 72 citations

[3] Joining of RNA molecules with RNA ligase

1983 • 71 citations

Chirally selective synthesis of sugar moiety of nucleosides by chemicoenzymatic approach: L- and D-riboses, showdomycin, and cordycepin

1981 • 71 citations

Chirale Verbindungen durch biokatalytische Reduktionen

1985 • 70 citations

Enzyme-catalyzed organic synthesis: regeneration of deuterated nicotinamide cofactors for use in large-scale enzymatic synthesis of deuterated substances

1983 • 69 citations

Enzymatic Approach to Syntheses of Unnatural Beta-Lactams

1984 • 69 citations

Preparation and use of insolubilized amyloglucosidase for the production of sweet glucose liquors

1969 • 69 citations

Hybrid organometallic/enzymic catalyst systems: regeneration of NADH using dihydrogen

1982 • 69 citations

Stereochemical course of 5-lipoxygenation of arachidonate by rat basophil leukemic cell (RBL-1) and potato enzymes

1983 • 69 citations

The Optical Rotation and Configuration of a Pure Enantiomorph of Ethanol-1-d^1,2,3

1957 • 67 citations

Enzyme als Gastmoleküle in inversen Micellen

1985 • 67 citations

Electro‐Enzymatic and Electro‐Microbial Stereospecific Reductions

1981 • 66 citations

Grundprinzipien der proteasekatalysierten Knüpfung der Peptidbindung

1985 • 66 citations

Nicotinamide coenzyme regeneration. Flavin mononucleotide (riboflavin phosphate) as an efficient, economical, and enzyme-compatible recycling agent

1976 • 66 citations

Large-scale enzyme-catalyzed synthesis of ATP from adenosine and acetyl phosphate. Regeneration of ATP from AMP

1978 • 66 citations

9-lR-linoleyl hydroperoxide, a novel product from the oxygenation of linoleic acid by type-2 lbpoxygenases from soybeans and peas

1979 • 66 citations

The Synthesis of Peptides by Means of Proteolytic Enzymes

1977 • 65 citations

Enzyme-catalyzed organic synthesis: NAD(P)H regeneration using dihydrogen and the hydrogenase from Methanobacterium thermoautotrophicum

1981 • 63 citations

Immobilized enzyme reaction stability: Attrition of the support material

1974 • 62 citations

Enzymes in organic synthesis. 16. Heterocyclic ketones as substrates of horse liver alcohol dehydrogenase. Stereospecific reductions of 2-substituted tetrahydrothiopyran-4-ones

1979 • 62 citations

Synthesis of the disaccharide 6-O-β-d-galactopyranosyl-2-acetamido-2-deoxy-d-galactose using immobilized β-galactosidase

1984 • 62 citations

Large-scale enzymic synthesis with cofactor regeneration: glucose 6-phosphate

1977 • 62 citations

The Microbiological Production of Industrial Chemicals

1981 • 61 citations

Herstellung und Verwendung von Aminosäuren

1978 • 60 citations

Enzyme-catalyzed organic synthesis: NAD(P)H cofactor regeneration using ethanol/alcohol dehydrogenase/aldehyde dehydrogenase and methanol/alcohol dehydrogenase/aldehyde dehydrogenase/formate dehydrogenase

1982 • 59 citations

Peptide synthesis catalyzed by papain at alkaline pH values

1984 • 59 citations

Asymmetric hydrolysis of (.+-.)-1,2-diacetoxy-3-chloropropane and its related compounds with lipase. Synthesis of optically pure (S)-propranolol.

1982 • 59 citations

Purification and Some Properties of a Hitherto‐Unknown Enzyme Reducing the Carbon‐Carbon Double Bond of α,β‐Unsaturated Carboxylate Anions

1979 • 58 citations

A new method to prepare amides by bioconversion of corresponding nitriles

1982 • 58 citations

Chirally selective synthesis of sugar moiety of nucleosides by chemicoenzymatic approach: L- and D-riboses, showdomycin, and cordycepin.

1981 • 57 citations

Synthesis and solution conformation of the type 2 blood group oligosaccharide .alpha.LFuc(1 .fwdarw. 2).beta.DGal(1 .fwdarw. 4).beta.DGlcNAc

1982 • 57 citations

ATP regeneration using immobilized carbamyl phosphokinase

1973 • 57 citations

Biotechnology and the fats and oils industry — An overview

1984 • 57 citations

New method for the synthesis of optically active .alpha.-amino acids and their N.alpha. derivatives via acylamino malonates

1973 • 55 citations

Practical enzymic syntheses of ribulose 1,5 bisphosphate and ribose 5-phosphate

1980 • 55 citations

[52] Production of 6-aminopenicillanic acid with immobilized Escherichia coli acylase

1976 • 55 citations

Human platelet activation by an alkylacetyl analogue of phosphatidylcholine

1982 • 54 citations

Combined electrochemical/enzymic method for in situ regeneration of NADH based on cathodic reduction of cyclic disulfides

1981 • 54 citations

Current Status of Asymmetric Synthesis

1983 • 53 citations

Synthesis with immobilized enzymes of two trisaccharides, one of them active as the determinant of a stage antigen.

1984 • 52 citations

Studies on polynucleotides. LXXXVII. The joining of short deoxyribopolynucleotides by DNA-joining enzymes.

1968 • 52 citations

Enantioselective hydrolysis of 3-hydroxy-3-methylalkanoic acid esters with pig liver esterase

1983 • 52 citations

Enzyme system generation of singlet (1.DELTA.g) molecular oxygen observed directly by 1.0-1.8-.mu. luminescence spectroscopy

1983 • 51 citations

Practical approach to high-yield enzymic stereospecific organic synthesis in multiphase systems

1981 • 51 citations

Acid-catalyzed hydration of reduced nicotinamide adenine dinucleotide and its analogs

1977 • 51 citations

Free and Immobilized Glucose Isomerase from Streptomyces phaeochromogenes

1971 • 51 citations

An efficient chemical and enzymic synthesis of nicotinamide adenine dinucleotide (NAD+)

1984 • 51 citations

Tartaric Acid Metabolism

1969 • 50 citations

Lipase-catalyzed production of optically active acids via asymmetric hydrolysis of esters

1984 • 50 citations

The regeneration of coenzymes using immobilized hydrogenase

1980 • 49 citations

A NMR shift method for determination of the enantiomeric composition of hydroperoxides formed by lipoxygenase

1979 • 49 citations

Stereospecific oxidation of aliphatic alcohols catalyzed by galactose oxidase

1982 • 49 citations

L-[4-11C]aspartic acid: enzymic synthesis, myocardial uptake, and metabolism

1982 • 49 citations

Kinetic studies of the mechanism of S-adenosylmethionine synthetase from yeast

1969 • 48 citations

Microbial and enzymatic processes for amino acid production

1978 • 47 citations

Enzymic synthesis of sn-glycerol 3-phosphate

1979 • 46 citations

The Biosynthesis of Cell Wall Lipopolysaccharide in Escherichia coli

1966 • 45 citations

[2] Using T4 RNA ligase with DNA substrates

1983 • 45 citations

Enzymes in organic synthesis. 31. Preparations of enantiomerically pure bicyclic [3.2.1] and [3.3.1] chiral lactones via stereospecific horse liver alcohol dehydrogenase catalyzed oxidations of meso diols

1984 • 44 citations

Stereospecific hydrolysis by soluble and immobilized lipases

1982 • 44 citations

LIPOXYGENASE PATHWAYS

1983 • 44 citations

Enzymatic conversion of DL-.ALPHA.-amino-.EPSILON.-caprolactam into L-lysine. I. Screening, classification and distribution of L-.ALPHA.-amino-.EPSILON.-caprolactam-hydrolyzing yeasts.

1976 • 44 citations

Preparative production of hydroquinone from benzoquinone catalysed by immobilized d-glucose oxidase

1982 • 44 citations

Enzymic synthesis of chemically unstable cardiac glycosides by β-galactosidase from Aspergillus oryzae

1984 • 42 citations

Asymmetric hydrolysis of esters by biochemical methods. Part V. Asymmetric hydrolysis of prochiral diesters with pig liver esterase. Preparation of optically active intermediates for the synthesis of (+)-biotin and (+)-.ALPHA.-methyl-3,4-dihydroxyphenylalanine.

1982 • 42 citations

Preparation of a mixture of nucleoside triphosphates from yeast RNA: use in enzymic synthesis requiring nucleoside triphosphate regeneration and conversion to nucleoside diphosphate sugars

1983 • 42 citations

Enantioselektive und enantiokonvergente Synthese von Bausteinen zur Totalsynthese cyclopentanoider Naturstoffe

1984 • 41 citations

T4 ribonucleic acid ligase joins single-strand oligo(deoxyribonucleotides)

1980 • 41 citations

Lipid Enzymes: Lipases, Lipoxygenases, and “Hydroperoxidases”

1980 • 40 citations

Comparative Studies on the Properties of Tryptophanase and Tyrosine Phenol‐lyase Immobilized Directly on Sepharose or by Use of Sepharose‐Bound Pyridoxal 5′‐Phosphate

1975 • 39 citations

Enzymes as reagents in the synthesis of peptides

1981 • 39 citations

Enzymatic synthesis of arginine phosphate with coupled ATP cofactor regeneration

1984 • 38 citations

Enzymic synthesis of dynorphin (1-8)

1982 • 38 citations

Microbial degradation of the phytosterol side chain. I. Enzymic conversion of 3-oxo-24-ethylcholest-4-en-26-oic acid into 3-oxochol-4-en-24-oic acid and androst-4-ene-3,17-dione

1982 • 38 citations

Glutathione production by immobilized Saccharomyces cerevisiae cells containing an ATP regeneration system

1981 • 38 citations

Synthesis of Phenylalanines in High Enantiomeric Excess via Enzymatic Resolution

1983 • 37 citations

Enantiomeric enrichment in the hydrolysis of oxazolones catalyzed by cyclodextrins or proteolytic enzymes

1980 • 37 citations

Enzymatic synthesis ofS-adenosyl-l-methionine froml-methionine and ATP

1983 • 37 citations

[35] N-asparagine-linked oligosaccharides: Biosynthesis of the lipid-linked oligosaccharides

1982 • 37 citations

Optimization of enzyme catalyzed peptide synthesis in a “water - water-immiscible organic solvent” biphasic system

1984 • 36 citations

Analyse von Struktur-Aktivitäts-Beziehungen bei Enzymen durch Protein-Engineering

1984 • 36 citations

REGENERATION OF NAD⁺ AND NADP⁺ COFACTORS BY PHOTOSENSITIZED ELECTRON TRANSFER

1982 • 35 citations

Stereoselectivity in the epoxide hydrolase catalyzed hydrolysis of the stereoisomeric 3-tert-butyl-1,2-epoxycyclohexanes. Further evidence for the topology of the enzyme active site

1982 • 34 citations

Specificities and properties of three reduced pyridine nucleotide-flavin mononucleotide reductases coupling to bacterial luciferase

1982 • 34 citations

Enzymatische Synthesen chiraler Bausteine aus prochiralenmeso-Substraten: Herstellung von Methyl(hydrogen)-1,2-cycloalkandicarboxylaten

1984 • 33 citations

[18] Synthesis of ribulose 1,5-bisphosphate: Routes from glucose 6-phosphate (via 6-phosphogluconate) and from adenosine monophosphate (via ribose 5-phosphate)

1982 • 33 citations

Coimmobilized multienzymes: An in vitro model for cellular processes

1983 • 33 citations

Regeneration of NAD(P)H using glucose-6-sulfate and glucose-6-phosphate dehydrogenase

1981 • 33 citations

Cholinesterase‐catalyzed resolution of <scp>D</scp>,<scp>L</scp>‐carnitine

1984 • 32 citations

Improved Microbial Production of Colominic Acid, a Homopolymer of N-Acetylneuraminic Acid

1973 • 32 citations

A simple synthesis of dl-chalcose

1982 • 32 citations

Partial Purification and Characterization of S -Adenosylhomocysteine Hydrolase Isolated from Saccharomyces cerevisiae

1972 • 31 citations

[14] Enzymic synthesis of13C-enriched aldoses, ketoses, and their phosphate esters

1982 • 31 citations

Stereochemical course of the biosynthesis of 1-aminocyclopropane-1-carboxylic acid. I. Role of the asymmetric sulfonium pole and the α-amino acid center

1984 • 31 citations

Immobilized enzymes in the production of radiopharmaceutically pure amino acids labeled with 13N.

1974 • 30 citations

Correlation studies based on enzyme structure and kinetic results: Deduction of productive substrate orientation in the active-site pocket of horse liver alcohol dehydrogenase

1981 • 29 citations

Elektro‐enzymatische und elektro‐mikrobielle stereospezifische Reduktionen

1981 • 29 citations

DMSO is a substrate for chloroperoxidase

1983 • 29 citations

Kinetics of chymotrypsin- and papain-catalysed synthesis of [leucine]enkephalin and [methionine]enkephalin

1984 • 29 citations

Studies of enzyme-mediated reactions. Part VII. Stereospecific syntheses of tritium-labelled (2R)- and (2S)-dopamines: stereochemical course of hydroxylation of dopamine by dopamine β-hydroxylase (E.C. 1.14.17.1)

1976 • 29 citations

Enzymic epoxidation of trans,trans-1,8-dideuterio-1,7-octadiene. Analysis using partially relaxed proton Fourier transform NMR

1977 • 28 citations

Free and Immobilized Glucose Isomerase from Streptomyces phaeochromogenes1

1971 • 28 citations

Insolubilized Glucoamylase Enzyme System for Continuous Production of Dextrose

1972 • 27 citations

濃縮と乾燥時の液状食品の芳香の回収と保存 I 加工法

1975 • 27 citations

Unusual steric course of the epoxide hydrolase-catalyzed hydrolysis of (.+-.)-3,4-epoxytetrahydropyran. A case of complete stereoconvergence

1981 • 27 citations

Polynucleotide phosphorylase covalently bound to cellulose and its use in the preparation of homopolynucleotides

1970 • 26 citations

[54] Scale-Up studies on immobilized, purified glucoamylase, covalently coupled to porous ceramic support

1976 • 26 citations

An improved synthesis of diammonium acetyl phosphate

1979 • 26 citations

Scale-Up Studies on Immobilized, Purified Glucoamylase, Covalently Coupled to Porous Ceramic Support

1975 • 26 citations

The microbial degradation of hydrocarbons

1984 • 25 citations

The enzymatic synthesis of heterogeneous dihalide derivatives: a unique biocatalytic discovery

1983 • 25 citations

Enzyme peptide synthesis by an iterative procedure in a nucleophile pool

1984 • 25 citations

A practical enzymic synthesis of (Sp)-adenosine 5'-O-(1-thiotriphosphate) ((Sp)-ATP-.alpha.-S)

1984 • 25 citations

Impacts of applied genetics; micro-organisms, plants and animals

1981 • 24 citations

The preparative synthesis of oligodeoxyribonucleotides using RNA ligase

1982 • 23 citations

Chapter 26. Enzymic Methods in Organic Synthesis

1984 • 23 citations

Large-scale synthesis of diammonium acetyl phosphate

1975 • 23 citations

Enzymatic synthesis of the penicillin and cephalosporin nuclei from an acyclic peptide containing carboxymethylcysteine

1984 • 22 citations

Synthesis of nicotinamide adenine dinucleotide (NAD) from adenosine monophosphate (AMP)

1980 • 22 citations

Insolubilized amylases

1973 • 21 citations

H. G. Gassen, A. Lang (Eds.): Chemical and Enzymatic Synthesis of Gene Fragments, Verlag Chemie Weinheim, Deerfield Beach‐Florida, Basel 1982. 260 Seiten, Preis: DM 78,—

1983 • 21 citations

Enzymatic Synthesis of a Sulfur-Analog of Penicillin Using the “cyclase” of Cephalosporium Acremonium

1984 • 20 citations

An improved synthesis of S-adenosylhomocysteine and related compounds

1984 • 20 citations

[58] On the potential of soluble and immobilized enzymes in synthetic organic chemistryf

1976 • 20 citations

Engineering enzymes

1984 • 20 citations

S-Adenosyl-L-Homocysteine: Simplified Enzymatical Preparation with High Yield

1982 • 18 citations

Conversion of the adenosine moieties of RNA into ATP for use in cofactor recycling

1979 • 18 citations

[10] Preparation, analysis, and biochemical applications of chiral methyl groups

1982 • 18 citations

Hydrolysis of adenosine 5'-triphosphate: an isotope-labeling study

1982 • 17 citations

Post-translational modification of proteins

1981 • 17 citations

Recombinant DNA Technology

1981 • 17 citations

Co-oligopeptides of glycine and aromatic amino acids with variable distance between the aromatic residues VIII. Enzymatic synthesis of N-protected dipeptide esters

1977 • 16 citations

Construction of a system for the regeneration of adenosine 5'-triphosphate, which supplies energy to bioreactor.

1984 • 15 citations

Enzymatic Synthesis of Pyridine Nucleotides. Structural Property of Some New NAD-analogs, and Base Conditions Available for the Analog Formation

1982 • 15 citations

Microbiological Synthesis of L-dopa

1974 • 15 citations

Practical enzymic synthesis of adenosine 5'-0-(3-thiotriphosphate) (ATP-.gamma.-S)

1984 • 14 citations

High yield synthesis of S-adenosylhomocysteine and related nucleosides by bacterial S-adenosylhomocysteine hydrolase.

1984 • 14 citations

Substrates of hydroxyketoglutarate aldolase

1984 • 14 citations

Synthesis by polymer-bound ribonuclease of the termination codons U-A-A, U-A-G, and U-G-A

1971 • 14 citations

Synthesis and properties of (4‐¹³C)NAD⁺

1984 • 13 citations

Kinetically controlled equilibria the perturbation of hydrolysis equilibria in reactions catalyzed by α-chymotrypsin immobilized on charges supports

1978 • 13 citations

Synthesis of .beta.-dihydrothebaine

1978 • 13 citations

The application of coenzyme-dependent enzymes in biotechnology

1983 • 13 citations

Preparation of optically pure N-tert-butyloxycarbonyl-O-benzyl-L-serine and its antipode

1978 • 13 citations

Enzyme-catalyzed transhydrogenation between nicotinamide cofactors and its application in organic synthesis

1982 • 12 citations

Use of immobilized carboxypeptidase Y (I-CPY) as a catalyst for deblocking in peptide synthesis

1980 • 12 citations

Enzymatic Synthesis of New Pyridine Nucleosides. Clitidine and Its Amide Derivative

1981 • 11 citations

An improved route to (3RS,5S)-[5-3H1]mevalonic acid

1975 • 11 citations

[Use of carrier bound leucine aminopeptidase from bovine lens for the racemic splitting of DL-amino acid amides].

1972 • 10 citations

Horse Liver Alcohol Dehydrogenase: An Illustrative Example of the Potential of Enzymes in Organic Synthesis

1982 • 10 citations

Enzymic resolution of (.+-.)-unsaturated cyclic terpene alcohols via asymmetric hydrolysis of corresponding acetates by microorganisms.

1980 • 10 citations

Synthesis of (+)-marmelo lactone A and (+)-marmelo lactone B.

1983 • 10 citations

Technische Mikrobiologie. Herausgegeben von H. Dellweg, 543 Seiten mit diversen Abb. und Tab., Verlag Versuchs‐ und Lehranstalt für Spiritusfabrikation und Fermentationstechnologie im Institut für Gärungsgewerbe und Biotechnologie, Berlin 1973

1976 • 10 citations

Abbau Von Steroiden

1971 • 9 citations

Bioconversion of lipophilic compounds by immobilized biocatalysts in organic solvents

1983 • 9 citations

ChemInform Abstract: ENZYMES IN ORGANIC SYNTHESIS. 16. HETEROCYCLIC KETONES AS SUBSTRATES OF HORSE E LIVER ALCOHOL DEHYDROGENASE. STEREOSPECIFIC REDUCTIONS OF 2‐SUBSTITUTED TETRAHYDROTHIOPYRAN‐4‐ONES

1979 • 9 citations

Production of Nicotinalnide Adenine Dinucleotide by Saecharomyces carlsbergensis

1973 • 9 citations

[60] Properties and applications of an immobilized mixed-function hepatic drug oxidase

1976 • 8 citations

Continuous ATP regeneration process with stable acetate kinase.

1984 • 8 citations

[59] The synthesis of porphobilinogen by immobilized δ-aminolevulinic acid dehydratase

1976 • 7 citations

Flavin Coenzyme Analogs as Probes of Flavoenzyme Reaction Mechanisms

1980 • 6 citations

Enzyme and Nonenzyme Hydrolyses of End Ester Group in Polyethylene Glycol Esters

1984 • 5 citations

ChemInform Abstract: AN EFFICIENT CHEMICAL AND ENZYMIC SYNTHESIS OF NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD+)

1984 • 5 citations

Enzymatic preparation of [U-14C]-4-chloronitrosobenzene

1983 • 3 citations

Industrial Enzymes from Microbial Sources. Herausgeg. von M. G. Halpern. Noyes Data Corp., Park Ridge – New Jersey/USA 1981. 1. Aufl., XII, 346 S., geb., $ 45,00

1983 • 3 citations

Case Studies of Nursing Intervention

1975 • 1 citations