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Evidence for a role of endogenous opioids in the nigrostriatal system: Influence of naloxone and morphine on nigrostriatal dopaminergic supersensitivity

Data up to Jan 2025

Published1983
Citations34
References46

Total Citations Per Year

Abstract

References (46)

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1973 • 811 citations

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1977 • 716 citations

Antagonism of Stimulation-Produced Analgesia by Naloxone, a Narcotic Antagonist

1976 • 664 citations

β-Endorphin Is Associated with Overeating in Genetically Obese Mice ( ob / ob ) and Rats ( fa / fa )

1978 • 474 citations

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1977 • 450 citations

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1977 • 312 citations

Stress-Induced Eating Is Mediated Through Endogenous Opiates

1980 • 296 citations

Effect of naloxone and morphine on various forms of memory in the rat: Possible role of endogenous opiate mechanisms in memory consolidation

1979 • 266 citations

β-Endorphin in vitro inhibition of striatal dopamine release

1976 • 252 citations

The relationship between striatal and mesolimbic dopamine dysfunction and the nature of circling responses following 6-hydroxydopamine and electrolytic lesions of the ascending dopamine systems of rat brain

1976 • 251 citations

Stimulation-produced Analgesia: Development of Tolerance and Cross-Tolerance to Morphine

1975 • 250 citations

Enhancement of Dopamine-Stimulated Adenylate Cyclase Activity in Rat Caudate after Lesions in Substantia Nigra: Evidence for Denervation Supersensitivity

1974 • 228 citations

Localization of opiate receptors and enkephalins in the rat striatum in relationship with the nigrostriatal dopaminergic system: lesion studies

1978 • 214 citations

Endorphins in Mental Health Research

1980 • 184 citations

Biogenic amines and narcotic effects. I. Modification of morphine-induced analgesia and motor activity after alteration of cerebral amine levels.

1973 • 172 citations

Opioids and rewarding brain stimulation

1978 • 139 citations

Chronic treatment with haloperidol accelerates the biosynthesis of enkephalins in rat striatum

1979 • 128 citations

Mediation of Diurnal Fluctuations in Pain Sensitivity in the Rat by Food Intake Patterns: Reversal by Naloxone

1980 • 102 citations

Radioimmunoassay of enkephalins

1977 • 98 citations

Influence of enkephalin on K+-evoked efflux of putative neurotransmitters in rat brain

1977 • 95 citations

Morphine differentially alters synthesis and turnover of dopamine in central neuronal systems

1980 • 82 citations

Morphine and ?9-tetrahydrocannabinol: Tolerance to the stimulus effects

1974 • 78 citations

An analysis at synaptic level of the morphine action in striatum and N. accumbens: Dopamine and acetylcholine interactions

1975 • 73 citations

Modulation of opiate receptor binding in striatum and amygdala by selective mesencephalic lesions

1980 • 61 citations

Blockade of central dopaminergic receptors of morphine: effect of haloperidol, apomorphine or benztropine.

1973 • 52 citations

Effects of opiates and opioid peptides on motor behaviors: sites and mechanisms of action

1979 • 51 citations

Circling behavior after narcotic drugs and during naloxone-precipitated abstinence in rats with unilateral nigral lesions.

1976 • 46 citations

Dopamine antagonist binding increases in two behaviorally distinct striatal denervation syndromes

1979 • 45 citations

Rat brain enkephalins: distribution and biosynthesis.

1978 • 43 citations

Actions of narcotics on brain dopamine metabolism and their relevance for "psychomotor" effects.

1976 • 34 citations

Modulation of striatal cyclic nucleotide phosphodiesterase by calmodulin: Regulation by opiate and dopamine receptor activation

1979 • 33 citations

Selective inhibition of mesolimbic behavioral supersensitivity by naloxone

1980 • 32 citations

Acute Effects of Narcotic Analgesics on Behavioral Arousal in the Rat

1973 • 26 citations

Radioimmunoassay of enkephalins: levels of methionine- and leucine-enkephalin in morphine-dependent and kainic acid-lesioned rat brains.

1978 • 25 citations

Differential effect of morphine on dopaminergic neurons in frontal cortex and striatum of the rat

1976 • 25 citations

Opiates and memory

1979 • 20 citations

Effect of morphine on dopaminergic neurons in the rat basal forebrain and striatum

1979 • 17 citations

Proceedings: The effects of buprenorphine, morphine and pentazocine on turning behaviour and stereotypy induced by apomorphine in the rat.

1975 • 17 citations

Effects of morphine on amphetamine-induced circling and striatal cyclic AMP in rats and mice

1979 • 12 citations

Changes in guanine nucleotide sensitive and insensitive 3H-ADTN binding in striatum following substantia nigra lesions

1980 • 11 citations

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