Effects of opiates and opioid peptides on motor behaviors: sites and mechanisms of action

Stereotaxic Mapping of the Monoamine Pathways in the Rat Brain*

1971 • 3,816 citations

Postsynaptic Supersensitivity after 6‐Hydroxy‐dopamine Induced Degeneration of the Nigro‐striatal Dopamine System

1971 • 1,922 citations

Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum

1975 • 1,741 citations

Frontiers in Catecholamine Research

1973 • 1,252 citations

Regional Distribution of Opiate Receptor Binding in Monkey and Human Brain

1973 • 811 citations

Immunohistochemical studies using antibodies to leucine-enkephalin: Initial observations on the nervous system of the rat

1976 • 767 citations

Dopamine Receptor Binding Enhancement Accompanies Lesion-Induced Behavioral Supersensitivity

1977 • 716 citations

Hippocampus and internal inhibition.

1968 • 677 citations

Opioid peptide enkephalin: immunohistochemical mapping in rat central nervous system.

1977 • 617 citations

Autoradiographic localization of opiate receptors in rat brain. II. The brain stem

1977 • 573 citations

[D-Ala ² ]-Met-Enkephalinamide: A Potent, Long-Lasting Synthetic Pentapeptide Analgesic

1976 • 466 citations

Frontiers in Catecholamine Research

1976 • 451 citations

Time‐dose relationships for locomotor activity effects of morphine after acute or repeated treatment

1972 • 439 citations

The C-Fragment of β-Lipotropin: An Endogenous Neuroleptic or Antipsychotogen?

1976 • 427 citations

Functional Role of the Nigro‐Neostriatal Dopamine Neurons*)

1966 • 394 citations

Morphine catalepsy in the rat: relation to striatal dopamine metabolism

1972 • 338 citations

Sites of morphine induced analgesia in the primate brain: relation to pain pathways

1974 • 332 citations

A functional effect of dopamine in the nucleus accumbens and in some other dopamine-rich parts of the rat brain

1975 • 323 citations

Determination of methionine enkephalin in discrete regions of rat brain

1977 • 280 citations

Paradoxical Effects after Microinjection of Morphine in the Periaqueductal Gray Matter in the Rat

1974 • 268 citations

On the central sites for the antinociceptive action of morphine and fentanyl

1970 • 265 citations

The relationship between striatal and mesolimbic dopamine dysfunction and the nature of circling responses following 6-hydroxydopamine and electrolytic lesions of the ascending dopamine systems of rat brain

1976 • 251 citations

Narcotic dependence, narcotic action and dopamine receptors

1975 • 225 citations

Stereotyped behaviour patterns and hyperactivity induced by amphetamine and apomorphine after discrete 6-hydroxydopamine lesions of extrapyramidal and mesolimbic nuclei

1977 • 225 citations

Neuroanatomical focus for morphine and enkaphalin-induced hypermotility

1977 • 209 citations

Turning behavior of mice with unilateral 6-hydroxydopamine lesions in the striatum: Effects of apomorphine, l-DOPA, amantadine, amphetamine and other psychomotor stimulants

1973 • 204 citations

Catecholamine Biosynthesis in Brains of Rats Treated with Morphine

1970 • 197 citations

Effects of morphine on striatal dopamine metabolism: Possible mechanism of its opposite effect on locomotor activity in rats and mice

1974 • 188 citations

The relative importance of dopaminergic and noradrenergic neuronal systems for the stimulation of locomotor activity induced by amphetamine and other drugs

1973 • 184 citations

Circling behavior in rats with 6-hydroxydopamine or electrolytic nigral lesions

1976 • 172 citations

Stereospecific and Nonstereospecific Effects of (+)- and (—)-Morphine: Evidence for a New Class of Receptors?

1977 • 164 citations

Analgesia and hyperreactivity produced by intracranial microinjections of morphine into the periaqueductal gray matter of the rat

1974 • 157 citations

Circling behavior and stereotypy induced by intranigral opiate microinjections.

1977 • 156 citations

β-Endorphin: Endogenous Opiate or Neuroleptic?

1977 • 127 citations

Morphine-induced muscular rigidity in rats

1973 • 125 citations

Effects of morphine intoxication on brain catecholamine neurons

1969 • 121 citations

Effect of apomorphine on motility in rats

1972 • 111 citations

Effect of intraventricular infusion of dopamine and norepinephrine on motor activity

1972 • 92 citations

Effects of humoral modulators and naloxone on morphine-induced changes in the spontaneous locomotor activity of the rat

1976 • 52 citations

Circling behavior after narcotic drugs and during naloxone-precipitated abstinence in rats with unilateral nigral lesions.

1976 • 46 citations

Decrease in morphine's analgesic action and increase in its cataleptic action by 6-hydroxydopamine injected bilaterally into caudate and putamen areas; partial restoration by l-DOPA plus decarboxylase inhibition

1973 • 41 citations

Effect of acute morphine administration on the metabolism of brain catecholamines

1973 • 36 citations

Apomorphine in the rat nucleus accumbens: Effects on the synthesis of 5-hydroxytryptamine and noradrenaline, the motor activity and the body temperature

1976 • 34 citations