In vivo MHC class II presentation of cytosolic proteins revealed by rapid automated tandem mass spectrometry and functional analyses

An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

1994 • 6,412 citations

Method to Correlate Tandem Mass Spectra of Modified Peptides to Amino Acid Sequences in the Protein Database

1995 • 1,269 citations

Sequence analysis of peptides bound to MHC class II molecules

1991 • 1,071 citations

A Receptor for the Selective Uptake and Degradation of Proteins by Lysosomes

1996 • 904 citations

Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles.

1993 • 900 citations

A Phagosome-to-Cytosol Pathway for Exogenous Antigens Presented on MHC Class I Molecules

1995 • 882 citations

Identification of self peptides bound to purified HLA-B27

1991 • 844 citations

Studies on the mechanisms of autophagy: formation of the autophagic vacuole.

1990 • 789 citations

Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

1992 • 763 citations

Peptides Presented to the Immune System by the Murine Class II Major Histocompatibility Complex Molecule I-A _d

1992 • 654 citations

Class I MHC presentation of exogenous soluble antigen via macropinocytosis in bone marrow macrophages

1995 • 416 citations

CD22 regulates thymus-independent responses and the lifespan of B cells

1996 • 395 citations

H2-M Mutant Mice Are Defective in the Peptide Loading of Class II Molecules, Antigen Presentation, and T Cell Repertoire Selection

1996 • 331 citations

Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis.

1995 • 300 citations

Class II MHC molecules can use the endogenous pathway of antigen presentation

1990 • 271 citations

Deficient Positive Selection of CD4 T Cells in Mice Displaying Altered Repertoires of MHC Class II–Bound Self-Peptides

1997 • 214 citations

HLA class II-restricted presentation of cytoplasmic measles virus antigens to cytotoxic T cells

1989 • 201 citations

Processing pathways for presentation of cytosolic antigen to MHC class II-restricted T cells

1992 • 201 citations

Human T cell response to the surface antigen of hepatitis B virus (HBsAg). Endosomal and nonendosomal processing pathways are accessible to both endogenous and exogenous antigen.

1988 • 180 citations

Identification of the naturally processed form of hen egg white lysozyme bound to the murine major histocompatibility complex class II molecule I-Ak.

1992 • 174 citations

Characterization of endogenous peptides bound to purified HLA-DR molecules and their absence from invariant chain-associated alpha beta dimers.

1993 • 145 citations

Antigen processing and presentation in transplantation

1996 • 140 citations

Uptake and degradation of proteins by isolated rat liver lysosomes. Suggestion of a microautophagic pathway of proteolysis.

1982 • 118 citations

Presentation of endogenous viral proteins in association with major histocompatibility complex class II: On the role of intracellular compartmentalization, invariant chain and the TAP transporter system

1995 • 106 citations

A study of complexes of class II invariant chain peptide: Major histocompatibility complex class II molecules using a new complex‐specific monoclonal antibody

1996 • 62 citations

Invariant Chain–independent Function of H-2M in the Formation of Endogenous Peptide–Major Histocompatibility Complex Class II Complexes In Vivo

1998 • 60 citations

Cloning of a rat cDNA encoding a novel LIM domain protein with high homology to rat RIL

1995 • 56 citations

Predominant HLA-class II bound self-peptides of a hematopoietic progenitor cell line are derived from intracellular proteins

1996 • 31 citations

Functional in vivo MHC class II loading by endogenously synthesized glycoprotein during viral infection.

1997 • 28 citations

Identification of self peptides bound to purified HLA-B27

1992 • 22 citations