Treatment of limited-stage small cell lung cancer: recent progress and future directions

A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate.

1979 • 1,331 citations

Important Advances in Oncology: 1986

1986 • 912 citations

A Southwest Oncology Group study

1993 • 778 citations

Importance of timing for thoracic irradiation in the combined modality treatment of limited-stage small-cell lung cancer. The National Cancer Institute of Canada Clinical Trials Group.

1993 • 716 citations

MACOP-B Chemotherapy for the Treatment of Diffuse Large-Cell Lymphoma

1985 • 677 citations

Randomized study of cyclophosphamide, doxorubicin, and vincristine versus etoposide and cisplatin versus alternation of these two regimens in extensive small-cell lung cancer: a phase III trial of the Southeastern Cancer Study Group.

1992 • 532 citations

The genetic origin of drug resistance in neoplasms: implications for systemic therapy.

1984 • 521 citations

Chemotherapy with or without Radiation Therapy in Limited Small-Cell Carcinoma of the Lung

1987 • 484 citations

Randomized Trial of Cyclophosphamide, Doxorubicin, and Vincristine Versus Cisplatin and Etoposide Versus Alternation of These Regimens in Small-Cell Lung Cancer

1991 • 444 citations

Tumor size, sensitivity to therapy, and design of treatment schedules.

1977 • 442 citations

The Norton-Simon hypothesis revisited.

1986 • 415 citations

Methods in Cancer Research

1979 • 318 citations

VP-16 and cisplatin as first-line therapy for small-cell lung cancer.

1985 • 301 citations

In vitro radiation and chemotherapy sensitivity of established cell lines of human small cell lung cancer and its large cell morphological variants.

1983 • 282 citations

Surgical resection in the management of small cell carcinoma of the lung

1982 • 255 citations

Superiority of Alternating Non-Cross-Resistant Chemotherapy in Extensive Small Cell Lung Cancer

1987 • 227 citations

Small cell lung cancer 1973–1983: Early progress and recent obstacles

1984 • 219 citations

Multimodal therapy for limited small-cell lung cancer: a randomized study of induction combination chemotherapy with or without thoracic radiation in complete responders; and with wide-field versus reduced-field radiation in partial responders: a Southwest Oncology Group Study.

1987 • 212 citations

Randomized trial of radiotherapy to the thorax in limited small-cell carcinoma of the lung treated with multiagent chemotherapy and elective brain irradiation: a preliminary report.

1984 • 206 citations

Late intensification chemotherapy with autologous bone marrow transplantation in selected small-cell carcinoma of the lung: a randomized study.

1987 • 204 citations

Concurrent chemotherapy/radiotherapy for limited small-cell lung carcinoma: a Southwest Oncology Group Study.

1990 • 195 citations

FIVE-YEAR FOLLOW-UP OF THE MEDICAL RESEARCH COUNCIL COMPARATIVE TRIAL OF SURGERY AND RADIOTHERAPY FOR THE PRIMARY TREATMENT OF SMALL-CELLED OR OAT-CELLED CARCINOMA OF THE BRONCHUS

1969 • 186 citations

Duration of chemotherapy in small cell lung cancer: a Cancer Research Campaign trial

1989 • 170 citations

Therapy of small cell lung cancer: a perspective on two decades of clinical research.

1988 • 168 citations

cis-Dichlorodiammineplatinum(II) and VP-16-213: an active induction regimen for small cell carcinoma of the lung.

1979 • 153 citations

Surgical treatment for limited small-cell lung cancer. The University of Toronto Lung Oncology Group experience.

1991 • 146 citations

Canadian multicenter randomized trial comparing sequential and alternating administration of two non-cross-resistant chemotherapy combinations in patients with limited small-cell carcinoma of the lung.

1987 • 146 citations

A preliminary report: Concurrent twice-daily radiotherapy plus platinum-etoposide chemotherapy for limited small cell lung cancer

1988 • 142 citations

Radiotherapy in small cell cancer of the lung treated with combination chemotherapy: a controlled trial.

1984 • 140 citations

Treatment sequencing, asymmetry, and uncertainty: protocol strategies for combination chemotherapy.

1986 • 134 citations

A randomized comparison of high-dose versus conventional-dose cyclophosphamide, doxorubicin, and vincristine for extensive-stage small-cell lung cancer: a phase III trial of the Southeastern Cancer Study Group.

1987 • 129 citations

Cisplatin plus etoposide consolidation following cyclophosphamide, doxorubicin, and vincristine in limited small-cell lung cancer.

1988 • 125 citations

Intensive weekly chemotherapy for the treatment of extensive-stage small-cell lung cancer.

1991 • 112 citations

Is there ever a role for salvage operations in limited small-cell lung cancer?

1991 • 97 citations

High-dose intensification therapy with autologous bone marrow support for limited small-cell bronchogenic carcinoma.

1986 • 87 citations

High-dose cyclophosphamide with autologous bone marrow rescue after conventional chemotherapy in the treatment of small cell lung carcinoma

1985 • 75 citations

Late intensive combined modality therapy followed by autologous bone marrow infusion in extensive-stage small-cell lung cancer.

1986 • 72 citations

Treatment of limited small-cell lung cancer with etoposide and cisplatin alternating with vincristine, doxorubicin, and cyclophosphamide versus concurrent etoposide, vincristine, doxorubicin, and cyclophosphamide and chest radiotherapy: a Southwest Oncology Group Study.

1990 • 68 citations

Heterogeneity in the Radiation Survival Curves and Biochemical Properties of Human Lung Cancer Cell Lines

1984 • 67 citations

The Feasibility of Adjuvant Surgery in Limited-Stage Small Cell Carcinoma: A Prospective Evaluation

1984 • 62 citations

Phase II trial of extended indications for resection is small cell carcinoma of the lung.

1982 • 61 citations

Treatment of limited-stage small-cell lung cancer with cyclophosphamide, doxorubicin, and vincristine with or without etoposide: a randomized trial of the North Central Cancer Treatment Group.

1990 • 57 citations

Phase II trial of extended indications for resection in small cell carcinoma of the lung

1982 • 56 citations

Etoposide combined with cyclophosphamide plus vincristine compared with doxorubicin plus cyclophosphamide plus vincristine and with high-dose cyclophosphamide plus vincristine in the treatment of small-cell carcinoma of the lung: a randomized trial of the Bristol Lung Cancer Study Group.

1989 • 55 citations

Intensive weekly chemotherapy for good-prognosis patients with small-cell lung cancer.

1991 • 54 citations

Current status of etoposide in the management of small cell lung cancer

1991 • 51 citations

VP-16-213 in combination chemotherapy with chest irradiation for small-cell lung cancer: a randomized trial of the Piedmont Oncology Association.

1984 • 46 citations

Dose-Time Relationships and the Local Control of Small Cell Carcinoma of the Lung

1978 • 46 citations

Surgery after initial chemotherapy for localized small-cell carcinoma of the lung.

1987 • 39 citations

Small cell carcinoma of the lung

1986 • 39 citations

Is thoracic radiation therapy necessary for patients with limited-stage small cell lung cancer? No.

1983 • 36 citations

Postchemotherapy Resection of Residual Tumor in Limited Stage Small Cell Lung Cancer

1987 • 32 citations

Treatment of small-cell lung cancer with an alternating chemotherapy regimen given at weekly intervals: a Southwest Oncology Group pilot study.

1990 • 30 citations

Cisplatin for small-cell lung cancer.

1989 • 30 citations

Etoposide and Split-Dose Cisplatin in Small-Cell Lung Cancer

1988 • 27 citations

Radiotherapy alone or with chemotherapy in the treatment of small-cell carcinoma of the lung

1981 • 26 citations

Combination cis-platinum and etoposide in small-cell lung cancer

1982 • 25 citations

Treatment of limited small-cell lung cancer with concurrent etoposide/cisplatin and radiotherapy followed by intensification with high-dose cyclophosphamide: a Southwest Oncology Group study.

1991 • 20 citations

The role of thoracic radiation therapy in small cell carcinoma of the lung: a concensus report

1989 • 15 citations

Limited small cell lung cancer--the role of radiotherapy.

1988 • 5 citations

Deleted Work

1955 • 0 citations