Canadian multicenter randomized trial comparing sequential and alternating administration of two non-cross-resistant chemotherapy combinations in patients with limited small-cell carcinoma of the lung.

Rationale for the use of alternating non-cross-resistant chemotherapy.

1982 • 545 citations

The genetic origin of drug resistance in neoplasms: implications for systemic therapy.

1984 • 521 citations

VP-16 and cisplatin as first-line therapy for small-cell lung cancer.

1985 • 301 citations

Small-Cell Carcinoma of the Lung: Combined Chemotherapy and Radiation

1978 • 232 citations

Small cell lung cancer 1973–1983: Early progress and recent obstacles

1984 • 219 citations

Etoposide (VP-16) and cisplatin: an effective treatment for relapse in small-cell lung cancer.

1985 • 188 citations

cis-Dichlorodiammineplatinum(II) and VP-16-213: an active induction regimen for small cell carcinoma of the lung.

1979 • 153 citations

Combination chemotherapy for small cell carcinoma of the lung: continuous versus alternating non-cross-resistant combinations.

1982 • 131 citations

Combined modality induction therapy without maintenance chemotherapy for small cell carcinoma of the lung.

1984 • 114 citations

Alternating radiotherapy and chemotherapy schedules in small cell lung cancer, limited disease

1985 • 100 citations

Chemotherapy strategies to improve the control of Hodgkin's disease: the Richard and Hinda Rosenthal Foundation Award Lecture.

1982 • 86 citations

Cisplatin and etoposide combination chemotherapy for refractory small cell carcinoma of the lung

1986 • 72 citations

Continuous versus alternating combination chemotherapy for advanced small cell carcinoma of the lung.

1983 • 66 citations

Current status of therapy for small cell carcinoma of the lung

1984 • 63 citations

Combined Modality Treatment of Small Cell Carcinoma of the Lung

1981 • 61 citations

Long-term survivors of small cell carcinoma of the lung

1985 • 60 citations

Application of theoretical models to chemotherapy protocol design.

1986 • 57 citations

Etoposide and cisplatin salvage chemotherapy for small cell lung cancer

1985 • 38 citations

Cyclic alternating 'non-cross resistant' chemotherapy in the management of small cell anaplastic carcinoma of the lung

1984 • 37 citations

Phase III study of CCNU, cyclophosphamide, adriamycin, vincristine, and VP-16 in small-cell carcinoma of the lung

1982 • 36 citations

Alternating chemotherapy and thoracic radiotherapy with concurrent cisplatin-etoposide for limited-stage small-cell carcinoma of the lung.

1986 • 33 citations

Evaluation of alternating chemotherapy and sites and extent of disease in extensive small cell lung cancer

1981 • 26 citations

Chemotherapy of small cell carcinoma of the lung: Comparison of a cyclic alternative combination with simultaneous combinations of four and seven agents

1981 • 20 citations

Controversies in Treatment of Small Cell Carcinoma of the Lung

1985 • 17 citations

A Controlled Clinical Trial Testing Two Potentially Non-Cross-Resistant Chemotherapeutic Regimens in Small-Cell Carcinoma of the Lung

1981 • 14 citations

Alternating non-cross-resistant drug combinations in the treatment of metastatic small-cell carcinoma of the lung.

1981 • 13 citations