Crystal structure of the anthrax lethal factor

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1997 • 33,348 citations

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Automated MAD and MIR structure solution

1999 • 3,079 citations

Raster3D Version 2.0. A program for photorealistic molecular graphics

1994 • 2,515 citations

Smallpox as a Biological Weapon

1999 • 1,565 citations

Proteolytic Inactivation of MAP-Kinase-Kinase by Anthrax Lethal Factor

1998 • 1,003 citations

Anthrax as a Biological Weapon

1999 • 896 citations

Anthrax

1999 • 841 citations

Crystal structure of the anthrax toxin protective antigen

1997 • 755 citations

A fast algorithm for rendering space-filling molecule pictures

1988 • 616 citations

The Comprehensive Sourcebook of Bacterial Protein Toxins

2015 • 601 citations

Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process.

1986 • 586 citations

Dali/FSSP classification of three-dimensional protein folds

1997 • 423 citations

Anthrax Lethal Factor Cleaves the N-Terminus of MAPKKs and Induces Tyrosine/Threonine Phosphorylation of MAPKs in Cultured Macrophages

1998 • 402 citations

Contribution of individual toxin components to virulence of Bacillus anthracis

1991 • 363 citations

Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor

2000 • 342 citations

Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity

1994 • 310 citations

On the role of macrophages in anthrax.

1993 • 305 citations

Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFNγ‐induced release of NO and TNFα

1999 • 296 citations

Identification of Residues Lining the Anthrax Protective Antigen Channel

1998 • 173 citations

NAD binding site of diphtheria toxin: identification of a residue within the nicotinamide subsite by photochemical modification with NAD.

1984 • 150 citations

Optimized Production and Purification of Bacillus anthracis Lethal Factor

2000 • 124 citations

Anthrax toxin-mediated delivery of a cytotoxic T-cell epitope in vivo.

1996 • 121 citations

Suppression of ras-mediated transformation and inhibition of tumor growth and angiogenesis by anthrax lethal factor, a proteolytic inhibitor of multiple MEK pathways

2001 • 108 citations

Targeting HIV proteins to the major histocompatibility complex class I processing pathway with a novel gp120-anthrax toxin fusion protein

1997 • 89 citations

Functional mapping of anthrax toxin lethal factor by in-frame insertion mutagenesis.

1991 • 83 citations

Arazoformyl Dipeptide Substrates for Thermolysin. Confirmation of a Reverse Protonation Catalytic Mechanism

1996 • 67 citations

CRYStallize: A crystallographic symmetry display and handling subpackage in TOM/FRODO

1990 • 53 citations

Involvement of Residues 147VYYEIGK153 in Binding of Lethal Factor to Protective Antigen of Bacillus anthracis

2001 • 31 citations

Secondary Structure of Anthrax Lethal Toxin Proteins and Their Interaction with Large Unilamellar Vesicles: A Fourier-Transform Infrared Spectroscopy Approach

1996 • 24 citations