Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFNγ‐induced release of NO and TNFα

NITRIC OXIDE AND MACROPHAGE FUNCTION

1997 • 4,106 citations

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

1989 • 3,477 citations

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

1994 • 3,285 citations

Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.

1988 • 2,865 citations

Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human

1999 • 2,692 citations

Proteolytic Inactivation of MAP-Kinase-Kinase by Anthrax Lethal Factor

1998 • 1,003 citations

Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells.

1982 • 929 citations

The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor.

1996 • 650 citations

Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process.

1986 • 586 citations

Anthrax Lethal Factor Cleaves the N-Terminus of MAPKKs and Induces Tyrosine/Threonine Phosphorylation of MAPKs in Cultured Macrophages

1998 • 402 citations

Contribution of individual toxin components to virulence of Bacillus anthracis

1991 • 363 citations

Germination of Bacillus anthracis spores within alveolar macrophages

1999 • 317 citations

On the role of macrophages in anthrax.

1993 • 305 citations

Cdc2 Kinase Directly Phosphorylates the cis-Golgi Matrix Protein GM130 and Is Required for Golgi Fragmentation in Mitosis

1998 • 283 citations

Differences in susceptibility of inbred mice to Bacillus anthracis

1986 • 282 citations

Protective antigen‐binding domain of anthrax lethal factor mediates translocation of a heterologous protein fused to its amino‐ or carboxy‐terminus

1995 • 164 citations

Yersinia enterocolitica Promotes Deactivation of Macrophage Mitogen-activated Protein Kinases Extracellular Signal-regulated Kinase-1/2, p38, and c-Jun NH2-terminal Kinase

1997 • 153 citations

Characterization of macrophage sensitivity and resistance to anthrax lethal toxin

1993 • 153 citations

Role of Macrophage Oxidative Burst in the Action of Anthrax Lethal Toxin

1994 • 138 citations

The Biogenetic Anatomy of Vitamin B6

1996 • 119 citations

Internalization and Processing of Bacillus anthracis Lethal Toxin by Toxin-sensitive and -resistant Cells

1989 • 110 citations

Different Mitogen-activated Protein Kinase Signaling Pathways Cooperate to Regulate Tumor Necrosis Factor α Gene Expression in T Lymphocytes

1999 • 102 citations

Biochemical and physiological changes induced by anthrax lethal toxin in J774 macrophage-like cells.

1992 • 102 citations

Pathogenesis and genetic control of resistance to the Sterne strain of Bacillus anthracis

1988 • 97 citations

The Three Factors of Anthrax Toxin: their Immunogenicity and Lack of Demonstrable Enzymic Activity

1963 • 82 citations

Ltx1, a mouse locus that influences the susceptibility of macrophages to cytolysis caused by intoxication with Bacillus anthracis lethal factor, maps to chromosome 11

1998 • 81 citations

Guidebook to protein toxins and their use in cell biology

1998 • 72 citations

Construction of Bacillus anthracis mutant strains producing a single toxin component

1993 • 70 citations

Anthrax toxin blocks priming of neutrophils by lipopolysaccharide and by muramyl dipeptide.

1986 • 60 citations

Nitric Oxide Regulates Interleukin 1 Bioactivity Released from Murine Macrophages

1996 • 58 citations

The vacuolar ATPase proton pump is required for the cytotoxicity of Bacillus anthracis lethal toxin

1996 • 46 citations

Protein synthesis is required for expression of anthrax lethal toxin cytotoxicity

1994 • 45 citations

The cytotoxic activity of Bacillus anthracis lethal factor is inhibited by leukotriene A4 hydrolase and metallopeptidase inhibitors

1996 • 42 citations

Mouse macrophage clones immortalized by retroviruses are functionally heterogeneous.

1991 • 38 citations

Cytotoxic effects of anthrax lethal toxin on macrophage-like cell line J774A.1

1996 • 38 citations

Guidebook to Protein Toxins and Their Use in Cell Biology

1997 • 37 citations

The Effects of pH on the Interaction of Anthrax Toxin Lethal and Edema Factors with Phospholipid Vesicles

1994 • 32 citations