T cell activation by a bispecific anti‐CD3/anti‐major histocompatibility complex class I antibody

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

[68] Transcription maps of polyoma virus-specific RNA: Analysis by two-dimensional nuclease S1 gel mapping

1980 • 1,430 citations

Antigen-specific interaction between T and B cells

1985 • 1,396 citations

Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores.

1985 • 742 citations

OKT3: a monoclonal anti-human T lymphocyte antibody with potent mitogenic properties.

1980 • 525 citations

Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway.

1984 • 506 citations

Heterogeneity among T cells in intracellular free calcium responses after mitogen stimulation with PHA or anti-CD3. Simultaneous use of indo-1 and immunofluorescence with flow cytometry.

1986 • 369 citations

Cloning and characterization of different human sequences related to the onc gene (v-myc) of avian myelocytomatosis virus (MC29).

1982 • 348 citations

Sequential expression of protooncogenes during lectin-stimulated mitogenesis of normal human lymphocytes.

1986 • 335 citations

Polymorphism in mitogenic effect of IgG1 monoclonal antibodies against T3 antigen on human T cells

1983 • 333 citations

Sequential expression of genes involved in human T lymphocyte growth and differentiation.

1985 • 291 citations

Stimulation of the T3-T cell receptor complex induces a membrane-potential-sensitive calcium influx

1985 • 282 citations

Leu 23 induction as an early marker of functional CD3/T cell antigen receptor triggering. Requirement for receptor cross-linking, prolonged elevation of intracellular [Ca++] and stimulation of protein kinase C.

1989 • 226 citations

The use of hybrid hybridomas to target human cytotoxic T lymphocytes

1987 • 199 citations

Complexity of the human T lymphocyte-specific cell surface antigen T3.

1982 • 170 citations

Early Signal Transduction by the Antigen Receptor Without Commitment to T Cell Activation

1988 • 169 citations

Interleukin 2 receptor gene expression in normal human T lymphocytes.

1985 • 164 citations

Synergism in the activation of human CD8 T cells by cross-linking the T-cell receptor complex with the CD8 differentiation antigen.

1986 • 159 citations

Activation of human T4 cells by cross-linking class I MHC molecules.

1988 • 75 citations

Coaggregation of the T-cell receptor with CD4 and other T-cell surface molecules enhances T-cell activation.

1987 • 71 citations

Functional analysis of a cytoplasmic domain-deleted mutant of the CD4 molecule.

1988 • 64 citations

Activation of T cells by cross‐linking an anti‐CD3 antibody with a second anti‐T cell antibody: mechanism and subset‐specific activation

1987 • 64 citations

Kinetics of MHC-antigen complex formation on antigen-presenting cells.

1988 • 63 citations

Triggering T cells by otherwise inert hybrid anti-CD3/antitumor antibodies requires encounter with the specific target cell.

1989 • 42 citations

Enhanced transmembrane signalling activity of monoclonal antibody heteroconjugates suggests molecular interactions between receptors on the T cell surface

1989 • 39 citations

T cell activation by cross‐linking anti‐CD3 antibodies with second anti‐T cell antibodies: dual antibody cross‐linking mimics physical monocyte interaction

1987 • 30 citations

Two monoclonal anti‐CD3 antibodies can induce different events in human T lymphocyte activation

1987 • 16 citations