Triggering T cells by otherwise inert hybrid anti-CD3/antitumor antibodies requires encounter with the specific target cell.

Hybrid hybridomas and their use in immunohistochemistry

1983 • 497 citations

Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex

1982 • 494 citations

Hybrid antibodies can target sites for attack by T cells

1985 • 479 citations

Specific targeting of cytotoxic T cells by anti-T3 linked to anti-target cell antibody

1985 • 339 citations

Polymorphism in mitogenic effect of IgG1 monoclonal antibodies against T3 antigen on human T cells

1983 • 333 citations

Stimulation of the T3-T cell receptor complex induces a membrane-potential-sensitive calcium influx

1985 • 282 citations

The use of hybrid hybridomas to target human cytotoxic T lymphocytes

1987 • 199 citations

Specific targeting of human peripheral blood T cells by heteroaggregates containing anti-T3 crosslinked to anti-target cell antibodies.

1986 • 94 citations

Therapeutic potential of monovalent monoclonal antibodies

1984 • 86 citations

Kinetics of MHC-antigen complex formation on antigen-presenting cells.

1988 • 63 citations

Use of anti-receptor antibodies to focus T-cell activity

1986 • 40 citations

Two monoclonal anti‐CD3 antibodies can induce different events in human T lymphocyte activation

1987 • 16 citations