Hepatocyte growth factor enhances adhesion of breast cancer cells to endothelial cells in vitro through up-regulation of CD44

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

1991 • 2,806 citations

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

1991 • 2,230 citations

Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins

1991 • 2,195 citations

A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells

1991 • 1,685 citations

CD44 and Its Interaction with Extracellular Matrix

1993 • 1,082 citations

CD44: Structure, Function and Association with the Malignant Process

1997 • 1,004 citations

Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: a new model for metastasis

2000 • 695 citations

Lymphocyte interactions with endothelial cells

1992 • 689 citations

A lymphocyte molecule implicated in lymph node homing is a member of the cartilage link protein family

1989 • 680 citations

Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by interferon gamma and is mediated by intercellular adhesion molecule 1 (ICAM-1).

1988 • 680 citations

Role of integrins and other cell adhesion molecules in tumor progression and metastasis.

1993 • 668 citations

The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesis.

1995 • 578 citations

Breast Cancer Cells Interact with Osteoblasts to Support Osteoclast Formation1

1999 • 524 citations

CD44 and its ligand hyaluronate mediate rolling under physiologic flow: a novel lymphocyte-endothelial cell primary adhesion pathway.

1996 • 421 citations

CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesion.

1992 • 383 citations

Four molecular pathways of T cell adhesion to endothelial cells: roles of LFA-1, VCAM-1, and ELAM-1 and changes in pathway hierarchy under different activation conditions.

1991 • 343 citations

Dual role of the CD44 molecule in T cell adhesion and activation.

1989 • 335 citations

Immunoreactive hepatocyte growth factor is a strong and independent predictor of recurrence and survival in human breast cancer.

1994 • 301 citations

Proteoglycan forms of the lymphocyte homing receptor CD44 are alternatively spliced variants containing the v3 exon.

1995 • 253 citations

The bisphosphonate ibandronate promotes apoptosis in MDA-MB-231 human breast cancer cells in bone metastases.

2001 • 244 citations

Heparan Sulfate-modified CD44 Promotes Hepatocyte Growth Factor/Scatter Factor-induced Signal Transduction through the Receptor Tyrosine Kinase c-Met

1999 • 231 citations

CD44: A Multitude of Isoforms with Diverse Functions

1993 • 229 citations

The role of cell adhesion molecules in cancer invasion and metastasis

1993 • 161 citations

Expression of the C-Met/HGF receptor in human breast carcinoma: Correlation with tumor progression

1997 • 153 citations

Comparison of immunohistochemistry and RT‐PCR for detection of CD44v‐expression, a new prognostic factor in human breast cancer

1995 • 150 citations

CD44 stimulation induces integrin-mediated adhesion of colon cancer cell lines to endothelial cells by up-regulation of integrins and c-Met and activation of integrins.

1999 • 147 citations

Hepatocyte growth factor and macrophage inflammatory protein 1 beta: structurally distinct cytokines that induce rapid cytoskeletal changes and subset-preferential migration in T cells.

1994 • 129 citations

Association of the HGF/SF Receptor, c-met, with the Cell-Surface Adhesion Molecule, E-Cadherin, and Catenins in Human Tumor Cells

1999 • 119 citations

Paracrine Regulation of Germinal Center B Cell Adhesion through the c-Met–Hepatocyte Growth Factor/Scatter Factor Pathway

1997 • 116 citations

Human microvessel endothelial cells: Isolation, culture and characterization

1993 • 108 citations

Serum concentrations of hepatocyte growth factor in breast cancer patients.

1995 • 104 citations

Hepatocyte Growth Factor/Scatter Factor Promotes Adhesion of Lymphoma Cells to Extracellular Matrix Molecules Via α4β1 and α5β1 Integrins

1997 • 100 citations

Cellular and molecular basis of preferential metastasis of breast cancer to bone

2000 • 94 citations

Expression of c-Met and Heparan-Sulfate Proteoglycan Forms of CD44 in Colorectal Cancer

2000 • 87 citations

Significance of circulating hepatocyte growth factor level as a prognostic indicator in primary breast cancer.

1998 • 86 citations

Isolation and culture of synovial microvascular endothelial cells. Characterization and assessment of adhesion molecule expression

1992 • 85 citations

Interleukin 15 Induces Endothelial Hyaluronan Expression in Vitro and Promotes Activated T Cell Extravasation through a Cd44-Dependent Pathway in Vivo

1999 • 78 citations

Constitutive Chemokine Production Results in Activation of Leukocyte Function-Associated Antigen-1 on Adult T-Cell Leukemia Cells

1998 • 75 citations

Heparan sulfate proteoglycan on leukemic cells is primarily involved in integrin triggering and its mediated adhesion to endothelial cells.

1996 • 62 citations

Modulation of cytokine function by heparan sulfate proteoglycans: sophisticated models for the regulation of cellular responses to cytokines.

1998 • 60 citations

Distinct phenotype of leukemic T cells with various tissue tropisms.

1997 • 58 citations

Hepatocyte growth factor/scatter factor expression and c-met in primary breast cancer

1996 • 55 citations

Heparan sulfate proteoglycan on endothelium efficiently induces integrin-mediated T cell adhesion by immobilizing chemokines in patients with rheumatoid synovitis

1998 • 52 citations

The Biochemistry of Metastasis

1996 • 50 citations

Human breast-cancer metastasis formation in a nude-mouse model: Studies of hyaluronidase, hyaluronan and hyaluronan-binding sites in metastatic cells

1999 • 47 citations

PTHrP and the PTH/PTHrP receptor are co-expressed in human breast and colon tumours

1997 • 43 citations

Serum concentration of hepatocyte growth factor in patients with metastatic breast cancer

1998 • 42 citations

Constitutive up-regulation of integrin-mediated adhesion of tumor-infiltrating lymphocytes to osteoblasts and bone marrow-derived stromal cells.

1998 • 38 citations

Regulation of Endothelial CD44 Expression and Endothelium–Tumour Cell Interactions by Hepatocyte Growth Factor/Scatter Factor

1997 • 38 citations

Hepatocyte growth factor is a potent trigger of neutrophil adhesion through rapid activation of lymphocyte function-associated antigen-1.

1998 • 37 citations

Differences between Bone Marrow and Lung Endothelial Cells

1998 • 7 citations