The exon trapping assay partly discriminates against alternatively spliced exons

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Basic local alignment search tool

1990 • 87,358 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

A rapid boiling method for the preparation of bacterial plasmids

1981 • 3,334 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

1989 • 2,308 citations

Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain.

1989 • 989 citations

Exon definition may facilitate splice site selection in RNAs with multiple exons.

1990 • 726 citations

Developmentally regulated expression of specific tau sequences

1989 • 589 citations

Structure and novel exons of the human .tau. gene

1992 • 587 citations

Tau Consists of a Set of Proteins with Repeated C-Terminal Microtubule-Binding Domains and Variable N-Terminal Domains

1989 • 478 citations

Exon amplification: a strategy to isolate mammalian genes based on RNA splicing.

1991 • 425 citations

The organization of 3' splice-site sequences in mammalian introns.

1989 • 310 citations

Structure of the bovine tau gene: alternatively spliced transcripts generate a protein family.

1989 • 306 citations

Exon Definition May Facilitate Splice Site Selection in RNAs with Multiple Exons

1990 • 269 citations

Selective Inactivation of the Exonuclease Activity of Bacteriophage T7 DNA Polymerase by in Vitro Mutagenesis

1989 • 258 citations

Cloning of a big tau microtubule-associated protein characteristic of the peripheral nervous system.

1992 • 249 citations

Primary structure of high molecular weight tau present in the peripheral nervous system.

1992 • 232 citations

Alpha-tropomyosin mutually exclusive exon selection: competition between branchpoint/polypyrimidine tracts determines default exon choice.

1991 • 146 citations

Rapid and efficient cloning of Alu-PCR products using uracil DNA glycosylase.

1991 • 105 citations

Nucleotide substitutions within the cardiac troponin T alternative exon disrupt pre-mRNA alternative splicing

1989 • 101 citations

Use of recombinant DNA technology to program eukaryotic cells to synthesize rat proinsulin: a rapid expression assay for cloned genes.

1982 • 69 citations

Optimal conditions for supercoil DNA sequencing with the Escherichia coli DNA polymerase I large fragment

1988 • 66 citations

Myosin light-chain 1/3 gene alternative splicing: cis regulation is based upon a hierarchical compatibility between splice sites.

1990 • 35 citations

Myosin Light-Chain 1/3 Gene Alternative Splicing: cis Regulation Is Based upon a Hierarchical Compatibility between Splice Sites

1990 • 8 citations