Molecular Basis for the Relationship Between Thrombosis and Cancer

Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1.

1986 • 1,079 citations

Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration.

1990 • 857 citations

Hemostasis and Thrombosis: Basic Principles and Clinical Practice

1994 • 723 citations

Role of tissue factor in embryonic blood vessel development

1996 • 693 citations

Activation of blood coagulation in cancer: Trousseau's syndrome revisited

1983 • 676 citations

Activation of blood coagulation in cancer: Trousseau's syndrome revisited

1983 • 590 citations

In situ detection of tissue factor in vascular endothelial cells: Correlation with the malignant phenotype of human breast disease

1996 • 544 citations

Cultured human endothelial cells generate tissue factor in response to endotoxin.

1983 • 516 citations

Phlegmasia alba dolens.

1865 • 503 citations

Tissue factor controls the balance of angiogenic and antiangiogenic properties of tumor cells in mice.

1994 • 488 citations

Structure and function of thrombomodulin: a natural anticoagulant

1990 • 385 citations

Clinique médicale de l'Hôtel-Dieu de Paris

1877 • 377 citations

Prevention of Venous Thromboembolism

1998 • 372 citations

Tumor necrosis factor leads to the internalization and degradation of thrombomodulin from the surface of bovine aortic endothelial cells in culture

1989 • 337 citations

Interleukin 1 induces endothelial cell synthesis of plasminogen activator inhibitor.

1986 • 326 citations

Structure and function of thrombomodulin: a natural anticoagulant

1990 • 318 citations

Regulation of vascular endothelial growth factor production and angiogenesis by the cytoplasmic tail of tissue factor

1999 • 316 citations

A Role for Tissue Factor in Cell Adhesion and Migration Mediated by Interaction with Actin-binding Protein 280

1998 • 313 citations

Hemostatic alterations in cancer patients

1992 • 284 citations

Pathophysiology of the Thrombophilic State in the Cancer Patient

1999 • 249 citations

Activation of coagulation and angiogenesis in cancer: immunohistochemical localization in situ of clotting proteins and vascular endothelial growth factor in human cancer.

1998 • 249 citations

Vascular Permeability Factor, Fibrin, and the Pathogenesis of Tumor Stroma Formationa

1992 • 235 citations

The Impact of All-trans-Retinoic Acid on the Coagulopathy of Acute Promyelocytic Leukemia

1998 • 213 citations

The tissue factor pathway of blood coagulation.

1992 • 212 citations

Regulation of Angiogenesis

1997 • 187 citations

Thrombosis and cancer

1987 • 170 citations

Hemostasis and thrombosis

2001 • 148 citations

Cancer and Thrombosis: from Phlegmasia Alba Dolens to Transgenic Mice

1995 • 141 citations

HYPERCOAGULABILITY IN CANCER

1996 • 137 citations

Loss of blast cell procoagulant activity and improvement of hemostatic variables in patients with acute promyelocytic leukemia administered all-trans-retinoic acid

1995 • 135 citations

A new procoagulant in acute leukemia

1988 • 128 citations

Cellular Receptors in the Regulation of Plasmin Generation

1995 • 120 citations

Cancer Procoagulant and Tissue Factor Are Differently Modulated by All-trans-Retinoic Acid in Acute Promyelocytic Leukemia Cells

1998 • 117 citations

Cancer procoagulant in human tumor cells: evidence from melanoma patients.

1986 • 113 citations

Progress of fibrinolysis during tumor necrosis factor infusions in humans. Concomitant increase in tissue-type plasminogen activator, plasminogen activator inhibitor type-1, and fibrin(ogen) degradation products

1990 • 109 citations

All-trans retinoic acid upregulates thrombomodulin and downregulates tissue-factor expression in acute promyelocytic leukemia cells: distinct expression of thrombomodulin and tissue factor in human leukemic cells

1994 • 101 citations

Tumor cell generation of thrombin via functional prothrombinase assembly.

1985 • 100 citations

Fibrin activation of vascular endothelial cells. Induction of IL-8 expression.

1995 • 99 citations

Potential role of interleukin-1 as the trigger for diffuse intravascular coagulation in acute nonlymphoblastic leukemia

1988 • 89 citations

Mechanisms of Hypercoagulation in Malignancy and during Chemotherapy

1998 • 81 citations

Tissue factor activity in leukemia cells. Special reference to disseminated intravascular coagulation

1987 • 78 citations

Antithrombotic Strategies in Patients with Cancer

1997 • 76 citations

Fibrinolysis and Cancer

1990 • 75 citations

Venous Thromboembolism in Malignancy and Malignancy in Venous Thromboembolism

1998 • 72 citations

Comparison of Procoagulant Activities in Extracts of Normal and Malignant Human Tissue<xref ref-type="fn" rid="FN2">2</xref>

1979 • 69 citations

New Insights into the Pathogenesis of Coagulation Dysfunction in Acute Promyelocytic Leukemia

1993 • 64 citations

Tissue transglutaminase expression in human breast cancer.

1996 • 63 citations

An enzyme-linked immunosorbent assay for cancer procoagulant and its potential as a new tumor marker.

1990 • 56 citations

Cancer Procoagulant in Acute Non Lymphoid Leukemia: Relationship of Enzyme Detection to Disease Activity

1990 • 56 citations

Effect of all-trans retinoic acid on procoagulant and fibrinolytic activities of cultured blast cells from patients with acute promyelocytic leukemia

1995 • 55 citations

All-trans-retinoic acid counteracts endothelial cell procoagulant activity induced by a human promyelocytic leukemia-derived cell line (NB4)

1996 • 54 citations

Tissue factor expression in human leukemic cells

1996 • 54 citations

Production of an active urokinase by leukemia cells: A novel distinction from cell lines of solid tumors

1988 • 53 citations

Cancer procoagulant in the human promyelocytic cell line NB4 and its modulation by all-trans-retinoic acid.

1994 • 51 citations

Regulation of angiogenesis

1997 • 46 citations

Molecular Mechanisms Linking Thrombosis and Angiogenesis in Cancer

1997 • 45 citations

Cancer procoagulant in acute lymphoblastic leukemia

1990 • 39 citations

Fibrin induction of tissue factor expression in human vascular endothelial cells.

1997 • 37 citations

Analysis of serum cancer procoagulant activity and its possible use as a tumor marker

1989 • 37 citations

Inhibitory Effect of Retinoids on the Generation of Procoagulant Activity by Blood Mononuclear Phagocytes

1991 • 36 citations

The site of activation of factor X by cancer procoagulant

1991 • 33 citations

Disorders of Thrombosis

1995 • 29 citations

Effects of dexamethasone on pro-inflammatory cytokine expression, cell growth and maturation during granulocytic differentiation of acute promyelocytic leukemia cells.

1995 • 29 citations

Three-stage chromogenic assay for the analysis of activation properties of factor X by cancer procoagulant

1993 • 27 citations

Treatment of Venous Thromboembolism in Cancer Patients

1998 • 21 citations

Procoagulant Activity of Human Stomach and Colon Cancers

1990 • 10 citations

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