Activation of coagulation and angiogenesis in cancer: immunohistochemical localization in situ of clotting proteins and vascular endothelial growth factor in human cancer.

Tumor Cells Secrete a Vascular Permeability Factor That Promotes Accumulation of Ascites Fluid

1983 • 3,942 citations

Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.

1995 • 3,139 citations

Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque.

1989 • 1,233 citations

Selective cellular expression of tissue factor in human tissues. Implications for disorders of hemostasis and thrombosis.

1989 • 1,199 citations

Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration.

1990 • 857 citations

Surface-dependent reactions of the vitamin K-dependent enzyme complexes

1990 • 853 citations

Activation of blood coagulation in cancer: Trousseau's syndrome revisited

1983 • 676 citations

In situ detection of tissue factor in vascular endothelial cells: Correlation with the malignant phenotype of human breast disease

1996 • 544 citations

Tissue factor controls the balance of angiogenic and antiangiogenic properties of tumor cells in mice.

1994 • 488 citations

Platelet-derived growth factor mRNA detection in human atherosclerotic plaques by in situ hybridization.

1988 • 481 citations

Tumor necrosis factor/cachectin increases permeability of endothelial cell monolayers by a mechanism involving regulatory G proteins.

1989 • 411 citations

Pathogenesis of tumor stroma generation: a critical role for leaky blood vessels and fibrin deposition

1989 • 386 citations

Expression of tissue factor, thrombomodulin, and E-selectin in baboons with lethal Escherichia coli sepsis.

1993 • 353 citations

Regulation of tissue factor gene expression in the monocyte procoagulant response to endotoxin.

1989 • 294 citations

Hemostatic alterations in cancer patients

1992 • 284 citations

Fundamental principles of in situ hybridization.

1993 • 242 citations

Abnormalities of blood coagulation in patients with cancer. Mononuclear cell tissue factor generation.

1981 • 212 citations

Coagulative properties of cancers

1958 • 201 citations

Monoclonal antibody analysis of purified and cell-associated tissue factor

1988 • 161 citations

Mononuclear cell tissue factor: cell of origin and requirements for activation

1979 • 160 citations

Specificity of a monoclonal antibody for the NH2-terminal region of fibrin

1984 • 141 citations

A new procoagulant in acute leukemia

1988 • 128 citations

Cancer procoagulant in human tumor cells: evidence from melanoma patients.

1986 • 113 citations

Tumor cell generation of thrombin via functional prothrombinase assembly.

1985 • 100 citations

Fibrin activation of vascular endothelial cells. Induction of IL-8 expression.

1995 • 99 citations

An anti-tissue factor monoclonal antibody which inhibits TF.VIIa complex is a potent anticoagulant in plasma.

1991 • 96 citations

Generation of procoagulant activity by mononuclear phagocytes: a possible mechanism contributing to blood clotting activation within malignant tissues

1983 • 93 citations

Tissue factor induction in human monocytes. Two distinct mechanisms displayed by different alloantigen-responsive T cell clones.

1985 • 87 citations

Monocyte procoagulant inducing factor: a lymphokine involved in the T cell-instructed monocyte procoagulant response to antigen.

1986 • 83 citations

Human monocytes are associated with the formation of fibrin.

1983 • 74 citations

Regulation of Tissue Factor Gene Expression in the Monocyte Procoagulant Response to Endotoxin†

1989 • 70 citations

Human tumor procoagulants: registry of the Subcommittee on Haemostasis and Malignancy of the Scientific and Standardization Committee, International Society on Thrombosis and Haemostasis.

1993 • 68 citations

IMMUNOHISTOLOGICAL ANALYSIS OF SERIAL BIOPSIES TAKEN DURING HUMAN RENAL ALLOGRAFT REJECTION

1985 • 67 citations

Abnormal regulation of coagulation/fibrinolysis in small cell carcinoma of the lung

1990 • 65 citations

The role of thrombin in tumor cell metastasis.

1994 • 59 citations

A monoclonal antibody with ability to distinguish between NH2-terminal fragments derived from fibrinogen and fibrin

1983 • 59 citations

Antimetastatic Agents. I. Role of Cellular Procoagulants in the Pathogenesis of Fibrin Deposition in Cancer and the Use of Anticoagulants and/or Antiplatelet Drugs in Cancer Treatment

1988 • 56 citations

An enzyme-linked immunosorbent assay for cancer procoagulant and its potential as a new tumor marker.

1990 • 56 citations

Tissue factor expression in human leukemic cells

1996 • 54 citations

Human breast and colon carcinomas express cysteine proteinase activities with pro‐aggregating and pro‐coagulant properties

1988 • 48 citations

Monocyte Procoagulant Activity as a Peripheral Marker of Clotting Activation in Cancer Patients

1988 • 42 citations

Cancer procoagulant in acute lymphoblastic leukemia

1990 • 39 citations

Fibrin induction of tissue factor expression in human vascular endothelial cells.

1997 • 37 citations

In situ characterization of antigenic and functional tissue factor expression in human tumors utilizing monoclonal antibodies and recombinant factor VIIa as probes.

1994 • 36 citations

Procoagulant activity of mononuclear phagocytes from different anatomical sites in patients with gynecological malignancies

1990 • 35 citations

Production and characterization of a monoclonal antibody (A1-3) that binds selectively to activated monocytes and inhibits monocyte procoagulant activity.

1986 • 23 citations

Animal Tumor Procoagulants: Registry of the Subcommittee on Haemostasis and Malignancy of the Scientific and Standardization Committee, International Society of Thrombosis and Haemostasis

1990 • 19 citations

Immunohistological studies with A1-3, a monoclonal antibody to activated human monocytes and macrophages.

1986 • 19 citations

Procoagulant activity of human alveolar macrophages: Different expression in patients with lung cancer

1986 • 18 citations

[78] Immunohistological studies with monoclonal antibodies

1986 • 16 citations

Antimetastatic Agents. II. Summary of the Interactions of Tumor Cells with Blood Coagulation Factors, Platelets, Fibrinolytic Factors, and Inflammatory Cells and Their Soluble Mediators: Potential for Therapeutic Interventions

1988 • 10 citations