Identification of p130Cas as a substrate of Yersinia YopH (Yop51), a bacterial protein tyrosine phosphatase that translocates into mammalian cells and targets focal adhesions

Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

1991 • 1,779 citations

Signal transduction from the extracellular matrix.

1993 • 1,727 citations

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

1992 • 1,456 citations

Integrin function: molecular hierarchies of cytoskeletal and signaling molecules.

1995 • 1,202 citations

MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo

1993 • 1,169 citations

A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner.

1994 • 653 citations

Characterization of plasmids and plasmid-associated determinants of Yersinia enterocolitica pathogenesis

1981 • 604 citations

Target cell contact triggers expression and polarized transfer of Yersinia YopE cytotoxin into mammalian cells.

1994 • 594 citations

Vinculin: A cytoskeletal target of the transforming protein of rous sarcoma virus

1981 • 591 citations

Protein Tyrosine Phosphatase Activity of an Essential Virulence Determinant in Yersinia

1990 • 566 citations

Translocation of a hybrid YopE‐adenylate cyclase from Yersinia enterocolitica into HeLa cells

1994 • 532 citations

Identification of the YopE and YopH domains required for secretion and internalization into the cytosol of macrophages, using the cyaA gene fusion approach.

1995 • 465 citations

Factors promoting acute and chronic diseases caused by yersiniae

1991 • 441 citations

Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas.

1995 • 423 citations

Induction of p130^cas Signaling Complex Formation upon Integrin-Mediated Cell Adhesion: a Role for Src Family Kinases

1996 • 422 citations

Tyrosine phosphate hydrolysis of host proteins by an essential Yersinia virulence determinant.

1991 • 393 citations

Direct Regulation of ZAP-70 by SHP-1 in T Cell Antigen Receptor Signaling

1996 • 390 citations

Intracellular targeting of the Yersinia YopE cytotoxin in mammalian cells induces actin microfilament disruption

1991 • 376 citations

The cytotoxic protein YopE of Yersinia obstructs the primary host defence

1990 • 372 citations

Signal transduction in the mammalian cell during bacterial attachment and entry

1993 • 364 citations

p130Cas, a Substrate Associated with v-Src and v-Crk, Localizes to Focal Adhesions and Binds to Focal Adhesion Kinase

1996 • 364 citations

Integrin-mediated Cell Adhesion Promotes Tyrosine Phosphorylation of p130Cas, a Src Homology 3-containing Molecule Having Multiple Src Homology 2-binding Motifs

1995 • 340 citations

The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions.

1995 • 329 citations

Inhibition of phagocytosis in Yersinia pseudotuberculosis: a virulence plasmid-encoded ability involving the Yop2b protein

1988 • 322 citations

The Interaction of Bacteria with Mammalian Cells

1992 • 304 citations

Tyrosine Phosphorylation of p130Cas and Cortactin Accompanies Integrin-mediated Cell Adhesion to Extracellular Matrix

1995 • 289 citations

Identification of p130^cas as a Substrate for the Cytosolic Protein Tyrosine Phosphatase PTP-PEST

1996 • 263 citations

Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts.

1993 • 257 citations

Cell‐surface‐bound Yersinia translocate the protein tyrosine phosphatase YopH by a polarized mechanism into the target cell

1995 • 246 citations

Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin.

1996 • 235 citations

Human Enhancer of Filamentation 1, a Novel p130^cas-Like Docking Protein, Associates with Focal Adhesion Kinase and Induces Pseudohyphal Growth in Saccharomyces cerevisiae

1996 • 233 citations

Direct Binding of C-terminal Region of p130 to SH2 and SH3 Domains of Src Kinase

1996 • 229 citations

Expression, purification, and physicochemical characterization of a recombinant Yersinia protein tyrosine phosphatase.

1992 • 228 citations

Electron microscopic evidence for in vivo extracellular localization of Yersinia pseudotuberculosis harboring the pYV plasmid

1990 • 224 citations

The SH2 and SH3 domains of pp60src direct stable association with tyrosine phosphorylated proteins p130 and p110.

1991 • 224 citations

Adhesion-induced tyrosine phosphorylation of the p130 SRC substrate

1995 • 223 citations

Daughter of Sevenless Is a Substrate of the Phosphotyrosine Phosphatase Corkscrew and Functions during Sevenless Signaling

1996 • 210 citations

Yops of Yersinia spp. pathogenic for humans

1993 • 209 citations

Functional conservation of the secretion and translocation machinery for virulence proteins of yersiniae, salmonellae and shigellae.

1995 • 205 citations

Binding and internalization of microorganisms by integrin receptors

1994 • 194 citations

Substrate specificity of the protein tyrosine phosphatases.

1993 • 189 citations

The Yersinia yop regulon

1989 • 182 citations

YopH of Yersinia pseudotuberculosis interrupts early phosphotyrosine signalling associated with phagocytosis

1996 • 168 citations

The Yersinia pseudotuberculosis adhesin YadA mediates intimate bacterial attachment to and entry into HEp-2 cells

1993 • 163 citations

Differential contribution of Yersinia enterocolitica virulence factors to evasion of microbicidal action of neutrophils

1996 • 161 citations

CROSS-TALK BETWEEN BACTERIAL PATHOGENS AND THEIR HOST CELLS

1996 • 153 citations

Dynamics of Oxidation of a Fe ²⁺ -Bearing Aluminosilicate (Basaltic) Melt

1996 • 148 citations

Inhibition of the Fc receptor-mediated oxidative burst in macrophages by the Yersinia pseudotuberculosis tyrosine phosphatase

1995 • 146 citations

The Yersinia tyrosine phosphatase: specificity of a bacterial virulence determinant for phosphoproteins in the J774A.1 macrophage.

1992 • 142 citations

Several GTP-binding Proteins, Including p21c-H-ras, Are Preferred Substrates of Pseudomonas aeruginosa Exoenzyme S

1989 • 126 citations

Regulation and polarized transfer of the Yersinia outer proteins (Yops) involved in antiphagocytosis

1994 • 126 citations

The role of protein tyrosine phosphorylation in integrin-mediated gene induction in monocytes.

1994 • 117 citations

Molecular cloning of a cDNA encoding a phosphoprotein, Efs, which contains a Src homology 3 domain and associates with Fyn.

1995 • 111 citations

Exploitation of host signal transduction pathways and cytoskeletal functions by invasive bacteria

1993 • 106 citations

Sequence specificity in recognition of the epidermal growth factor receptor by protein tyrosine phosphatase 1B.

1993 • 99 citations

The identification of p130cas-binding proteins and their role in cellular transformation.

1996 • 98 citations

Cloning the structural gene for the 49-kDa form of exoenzyme S (exoS) from Pseudomonas aeruginosa strain 388.

1994 • 95 citations

Adhesion through the Interaction of Lymphocyte Function-associated Antigen-1 with Intracellular Adhesion Molecule-1 Induces Tyrosine Phosphorylation of p130 and Its Association with c-CrkII

1996 • 81 citations

Essential role of YopD in inhibition of the respiratory burst of macrophages by Yersinia enterocolitica

1994 • 79 citations

Identification and Characterization of a High-Affinity Interaction Between v-Crk and Tyrosine-Phosphorylated Paxillin in CT10-Transformed Fibroblasts

1993 • 71 citations

Determinants for thermoinducible cell binding and plasmid-encoded cellular penetration detected in the absence of the Yersinia pseudotuberculosis invasin protein

1989 • 68 citations

Salmonella entry into mammalian cells: different yet converging signal transduction pathways?

1994 • 32 citations

How pathogens expolit interactions mediated by SH3 domains

1996 • 30 citations

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