The dynamic organization of postsynaptic proteins: translocating molecules regulate synaptic function

Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex

2002 • 1,906 citations

Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons

2001 • 1,523 citations

Driving AMPA Receptors into Synapses by LTP and CaMKII: Requirement for GluR1 and PDZ Domain Interaction

2000 • 1,507 citations

Rapid Spine Delivery and Redistribution of AMPA Receptors After Synaptic NMDA Receptor Activation

1999 • 1,272 citations

PSD-95 Involvement in Maturation of Excitatory Synapses

2000 • 1,238 citations

Long-term dendritic spine stability in the adult cortex

2002 • 1,186 citations

Single particle tracking. Analysis of diffusion and flow in two-dimensional systems

1991 • 1,120 citations

Subunit-Specific Rules Governing AMPA Receptor Trafficking to Synapses in Hippocampal Pyramidal Neurons

2001 • 1,073 citations

Confined lateral diffusion of membrane receptors as studied by single particle tracking (nanovid microscopy). Effects of calcium-induced differentiation in cultured epithelial cells

1993 • 1,002 citations

Homer Binds a Novel Proline-Rich Motif and Links Group 1 Metabotropic Glutamate Receptors with IP3 Receptors

1998 • 852 citations

Evidence for a Role of Dendritic Filopodia in Synaptogenesis and Spine Formation

1996 • 844 citations

Cell Type and Pathway Dependence of Synaptic AMPA Receptor Number and Variability in the Hippocampus

1998 • 798 citations

Signal-Processing Machines at the Postsynaptic Density

2000 • 792 citations

Postsynaptic Signaling and Plasticity Mechanisms

2002 • 713 citations

Kinesin Superfamily Motor Protein KIF17 and mLin-10 in NMDA Receptor-Containing Vesicle Transport

2000 • 700 citations

Interaction with the NMDA receptor locks CaMKII in an active conformation

2001 • 695 citations

Regulation of Dendritic Spine Morphology and Synaptic Function by Shank and Homer

2001 • 685 citations

Different modes of expression of AMPA and NMDA receptors in hippocampal synapses

1999 • 673 citations

Dynamic Control of CaMKII Translocation and Localization in Hippocampal Neurons by NMDA Receptor Stimulation

1999 • 652 citations

The Dynamics of Dendritic Structure in Developing Hippocampal Slices

1996 • 611 citations

Assembly of presynaptic active zones from cytoplasmic transport packets

2000 • 602 citations

Synaptic Strength Regulated by Palmitate Cycling on PSD-95

2002 • 547 citations

NSF Binding to GluR2 Regulates Synaptic Transmission

1998 • 542 citations

Regulation of AMPA receptor lateral movements

2002 • 518 citations

Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites

2002 • 517 citations

Selective acquisition of AMPA receptors over postnatal development suggests a molecular basis for silent synapses

1999 • 496 citations

Assembly of New Individual Excitatory Synapses

2000 • 490 citations

Rapid turnover of actin in dendritic spines and its regulation by activity

2002 • 466 citations

Clathrin Adaptor AP2 and NSF Interact with Overlapping Sites of GluR2 and Play Distinct Roles in AMPA Receptor Trafficking and Hippocampal LTD

2002 • 437 citations

Dynamin-dependent endocytosis of ionotropic glutamate receptors

1999 • 425 citations

Protein kinase C modulates NMDA receptor trafficking and gating

2001 • 418 citations

An NMDA Receptor ER Retention Signal Regulated by Phosphorylation and Alternative Splicing

2001 • 414 citations

Mobile NMDA Receptors at Hippocampal Synapses

2002 • 413 citations

Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer

2001 • 397 citations

Interaction of the N-Ethylmaleimide–Sensitive Factor with AMPA Receptors

1998 • 396 citations

Regulation of Dendritic Spine Morphology by SPAR, a PSD-95-Associated RapGAP

2001 • 383 citations

LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1

2001 • 353 citations

Ligand-Gated Ion Channel Interactions with Cytoskeletal and Signaling Proteins

2000 • 352 citations

PDZ Domain Suppression of an ER Retention Signal in NMDA Receptor NR1 Splice Variants

2000 • 344 citations

Activity differentially regulates the surface expression of synaptic AMPA and NMDA glutamate receptors

1998 • 336 citations

Synaptic Targeting of the Postsynaptic Density Protein PSD-95 Mediated by Lipid and Protein Motifs

1999 • 327 citations

NMDA receptor trafficking through an interaction between PDZ proteins and the exocyst complex

2003 • 323 citations

SNAREs and NSF in targeted membrane fusion

1997 • 301 citations

Rapid formation and remodeling of postsynaptic densities in developing dendrites

2001 • 298 citations

Spine Formation and Correlated Assembly of Presynaptic and Postsynaptic Molecules

2001 • 288 citations

Rapid recruitment of NMDA receptor transport packets to nascent synapses

2002 • 283 citations

Molecular mechanisms of glutamate receptor clustering at excitatory synapses

1998 • 273 citations

Interaction of the Postsynaptic Density-95/Guanylate Kinase Domain-Associated Protein Complex with a Light Chain of Myosin-V and Dynein

2000 • 250 citations

A use-dependent tyrosine dephosphorylation of NMDA receptors is independent of ion flux

2001 • 245 citations

Continual remodeling of postsynaptic density and its regulation by synaptic activity

1999 • 244 citations

Homer 1b Regulates the Trafficking of Group I Metabotropic Glutamate Receptors

1999 • 211 citations

Molecular memory by reversible translocation of calcium/calmodulin-dependent protein kinase II

2000 • 205 citations

Molecular mechanisms of CNS synaptogenesis

2002 • 204 citations

Molecular mechanisms of CaMKII activation in neuronal plasticity

2002 • 196 citations

Receptor Activation and Homer Differentially Control the Lateral Mobility of Metabotropic Glutamate Receptor 5 in the Neuronal Membrane

2002 • 165 citations

Differential regulation of synaptic and extra-synaptic NMDA receptors

2002 • 160 citations

Rapid Synaptic Remodeling by Protein Kinase C: Reciprocal Translocation of NMDA Receptors and Calcium/Calmodulin-Dependent Kinase II

2002 • 152 citations

Modular Transport of Postsynaptic Density-95 Clusters and Association with Stable Spine Precursors during Early Development of Cortical Neurons

2001 • 125 citations

Rapid Redistribution of the Postsynaptic Density Protein PSD-Zip45 (Homer 1c) and Its Differential Regulation by NMDA Receptors and Calcium Channels

2001 • 122 citations

The Dynamics of SAP90/PSD-95 Recruitment to New Synaptic Junctions

2001 • 122 citations

Homer-1c/Vesl-1L Modulates the Cell Surface Targeting of Metabotropic Glutamate Receptor Type 1α: Evidence for an Anchoring Function

2000 • 114 citations

Cupidin, an Isoform of Homer/Vesl, Interacts with the Actin Cytoskeleton and Activated Rho Family Small GTPases and Is Expressed in Developing Mouse Cerebellar Granule Cells

1999 • 103 citations

Synchronized Formation and Remodeling of Postsynaptic Densities: Long-Term Visualization of Hippocampal Neurons Expressing Postsynaptic Density Proteins Tagged with Green Fluorescent Protein

2003 • 78 citations

Polarized Targeting of Peripheral Membrane Proteins in Neurons

2001 • 75 citations

Molecular morphogens for dendritic spines

2002 • 74 citations

Synaptic Targeting of PSD-Zip45 (Homer 1c) and Its Involvement in the Synaptic Accumulation of F-actin

2003 • 46 citations

The arrangement of actin filaments in the postsynaptic cytoplasm of the cerebellar cortex revealed by quick-freeze deep-etch electron microscopy

1989 • 32 citations

Effects of coexpression with Homer isoforms on the function of metabotropic glutamate receptor 1α

2003 • 32 citations

Visualizing synapse formation and remodeling: recent advances in real-time imaging of CNS synapses

2001 • 15 citations