Synaptic Targeting of the Postsynaptic Density Protein PSD-95 Mediated by Lipid and Protein Motifs

Functional rafts in cell membranes

1997 • 9,471 citations

Optimized survival of hippocampal neurons in B27‐supplemented neurobasal™, a new serum‐free medium combination

1993 • 2,272 citations

Domain Interaction Between NMDA Receptor Subunits and the Postsynaptic Density Protein PSD-95

1995 • 1,861 citations

Interaction of Nitric Oxide Synthase with the Postsynaptic Density Protein PSD-95 and α1-Syntrophin Mediated by PDZ Domains

1996 • 1,589 citations

Cloning and characterization of chi-1: a developmentally regulated member of a novel class of the ionotropic glutamate receptor family

1995 • 1,252 citations

The rat brain postsynaptic density fraction contains a homolog of the drosophila discs-large tumor suppressor protein

1992 • 1,180 citations

Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases

1995 • 994 citations

Interaction of Tyrosine-Based Sorting Signals with Clathrin-Associated Proteins

1995 • 955 citations

Defective Neuromuscular Synaptogenesis in Agrin-Deficient Mutant Mice

1996 • 915 citations

The Receptor Tyrosine Kinase MuSK Is Required for Neuromuscular Junction Formation In Vivo

1996 • 881 citations

Binding of Neuroligins to PSD-95

1997 • 731 citations

Agrin Acts via a MuSK Receptor Complex

1996 • 653 citations

The Agrin Hypothesis

1990 • 637 citations

SynGAP: a Synaptic RasGAP that Associates with the PSD-95/SAP90 Protein Family

1998 • 617 citations

Biochemical and immunochemical evidence that the "major postsynaptic density protein" is a subunit of a calmodulin-dependent protein kinase.

1983 • 617 citations

Caveolae: where incoming and outgoing messengers meet.

1993 • 616 citations

A Synaptic Ras-GTPase Activating Protein (p135 SynGAP) Inhibited by CaM Kinase II

1998 • 578 citations

A Tripartite Protein Complex with the Potential to Couple Synaptic Vesicle Exocytosis to Cell Adhesion in Brain

1998 • 548 citations

Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice

1995 • 530 citations

GKAP, a Novel Synaptic Protein That Interacts with the Guanylate Kinase-like Domain of the PSD-95/SAP90 Family of Channel Clustering Molecules

1997 • 503 citations

PDZ Proteins Organize Synaptic Signaling Pathways

1998 • 474 citations

Polarized sorting of viral glycoproteins to the axon and dendrites of hippocampal neurons in culture

1990 • 425 citations

SAP90, a rat presynaptic protein related to the product of the Drosophila tumor suppressor gene dlg-A.

1993 • 415 citations

Regulation of Synapse Structure and Function by the Drosophila Tumor Suppressor Gene dlg

1996 • 411 citations

Heterogeneity in the Molecular Composition of Excitatory Postsynaptic Sites during Development of Hippocampal Neurons in Culture

1998 • 396 citations

Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein

1995 • 388 citations

Basolateral sorting of LDL receptor in MDCK cells: The cytoplasmic domain contains two tyrosine-dependent targeting determinants

1992 • 366 citations

The LIN-2/LIN-7/LIN-10 Complex Mediates Basolateral Membrane Localization of the C. elegans EGF Receptor LET-23 in Vulval Epithelial Cells

1998 • 366 citations

Cloning and characterization of hdlg: the human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1.

1994 • 365 citations

Interaction of ion channels and receptors with PDZ domain proteins

1997 • 362 citations

SAPAPs

1997 • 356 citations

Cloning and Characterization of Postsynaptic Density 93, a Nitric Oxide Synthase Interacting Protein

1996 • 327 citations

The isolation and sequence of the gene encoding T8: A molecule defining functional classes of T lymphocytes

1985 • 325 citations

PDZs and Receptor/Channel Clustering: Rounding Up the Latest Suspects

1996 • 322 citations

The dynamic role of palmitoylation in signal transduction

1995 • 315 citations

CRIPT, a Novel Postsynaptic Protein that Binds to the Third PDZ Domain of PSD-95/SAP90

1998 • 304 citations

N-Terminal Palmitoylation of PSD-95 Regulates Association with Cell Membranes and Interaction with K+ Channel Kv1.4

1998 • 292 citations

Induction of long-term potentiation is associated with an increase in the number of axospinous synapses with segmented postsynaptic densities

1991 • 272 citations

LIN-10 Is a Shared Component of the Polarized Protein Localization Pathways in Neurons and Epithelia

1998 • 271 citations

Binding of the Inward Rectifier K+ Channel Kir 2.3 to PSD-95 Is Regulated by Protein Kinase A Phosphorylation

1996 • 265 citations

Essential Role fordlgin Synaptic Clustering of Shaker K⁺ChannelsIn Vivo

1997 • 262 citations

Reversible palmitoylation of signaling proteins

1997 • 256 citations

Neuronal polarity: Essential role of protein–lipid complexes in axonal sorting

1998 • 222 citations

Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the chain of adaptor complexes

1998 • 209 citations

Synaptic Clustering of Fasciclin II and Shaker: Essential Targeting Sequences and Role of Dlg

1997 • 208 citations

Synaptic Clustering of the Cell Adhesion Molecule Fasciclin II by Discs-Large and its Role in the Regulation of Presynaptic Structure

1997 • 208 citations

Disulfide-Linked Head-to-Head Multimerization in the Mechanism of Ion Channel Clustering by PSD-95

1997 • 207 citations

Localization of Postsynaptic Density-93 to Dendritic Microtubules and Interaction with Microtubule-Associated Protein 1A

1998 • 204 citations

Signal transduction molecules at the glutamatergic postsynaptic membrane1Published on the World Wide Web on 24 October 1997.1

1998 • 184 citations

Function of a calmodulin in postsynaptic densities. III. Calmodulin-binding proteins of the postsynaptic density.

1981 • 179 citations

The Polarized Sorting of Membrane Proteins Expressed in Cultured Hippocampal Neurons Using Viral Vectors

1998 • 175 citations

Regulation and Function of the CD3γ DxxxLL Motif: A Binding Site for Adaptor Protein-1 and Adaptor Protein-2 in Vitro

1997 • 171 citations

Isoform Specificity in the Relationship of Actin to Dendritic Spines

1997 • 152 citations

A functional barrier to movement of lipids in polarized neurons

1992 • 147 citations

Caveolae, transmembrane signalling and cellular transformation

1995 • 139 citations

Subcellular targeting and cytoskeletal attachment of SAP97 to the epithelial lateral membrane

1998 • 137 citations

Organizing a functional junctional complex requires specific domains of the Drosophila MAGUK Discs large

1997 • 136 citations

Characterization of Guanylate Kinase-Associated Protein, a Postsynaptic Density Protein at Excitatory Synapses That Interacts Directly with Postsynaptic Density-95/Synapse-Associated Protein 90

1997 • 122 citations

Identification of the mouse muscle 43,000-dalton acetylcholine receptor-associated protein (RAPsyn) by cDNA cloning.

1988 • 98 citations

Critical residues in an SH3 domain from Sem-5 suggest a mechanism for proline-rich peptide recognition

1994 • 97 citations

Improved lipid-mediated gene transfer into primary cultures of hippocampal neurons

1996 • 47 citations

Proteins of the Synaptic Junction

1975 • 46 citations

Influence of the Postsynaptic Target on the Functional Properties of Neurons in the Adult Mammalian Central Nervous System

1996 • 44 citations