Telomeres — what's new at the end?

Structure and function of telomeres

1991 • 3,524 citations

Identification of a specific telomere terminal transferase activity in tetrahymena extracts

1985 • 3,331 citations

A theory of marginotomy

1973 • 1,770 citations

Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis

1988 • 1,734 citations

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

1989 • 1,607 citations

Origin of Concatemeric T7DNA

1972 • 1,591 citations

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

1989 • 1,509 citations

HELIX FORMATION BY GUANYLIC ACID

1962 • 1,478 citations

Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription

1990 • 1,343 citations

Monovalent cation-induced structure of telomeric DNA: The G-quartet model

1989 • 1,202 citations

Telomere loss: mitotic clock or genetic time bomb?

1991 • 1,144 citations

The telomere terminal transferase of tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

1987 • 1,127 citations

Inhibition of telomerase by G-quartet DMA structures

1991 • 1,086 citations

Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops

1989 • 939 citations

A mutant with a defect in telomere elongation leads to senescence in yeast

1989 • 905 citations

A sodium-potassium switch in the formation of four-stranded G4-DNA

1990 • 789 citations

Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae

1991 • 700 citations

THE MOLECULAR STRUCTURE OF CENTROMERES AND TELOMERES

1984 • 693 citations

Telomeric DNA oligonucleotides form novel intramolecular structures containing guanine·guanine base pairs

1987 • 675 citations

In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs

1990 • 632 citations

STRUCTURE AND FUNCTION OF TELOMERES

1989 • 604 citations

Two DNA-binding factors recognize specific sequences at silencers, upstream activating sequences, autonomously replicating sequences, and telomeres in Saccharomyces cerevisiae.

1988 • 511 citations

RAP1 protein interacts with yeast telomeres in vivo: Overproduction alters telomere structure and decreases chromosome stability

1990 • 436 citations

Distribution patterns of HP1, a heterochromatin-associated nonhistone chromosomal protein of Drosophila.

1989 • 400 citations

Functional Evidence for an RNA Template in Telomerase

1990 • 392 citations

Epigenetic inheritance of transcriptional states in S. cerevisiae

1989 • 327 citations

Involvement of the Silencer and UAS Binding Protein RAP1 in Regulation of Telomere Length

1990 • 326 citations

A truncated human chromosome 16 associated with α thalassaemia is stabilized by addition of telomeric repeat (TTAGGG)n

1990 • 288 citations

Connections Between Transcriptional Activators, Silencers, and Telomeres as Revealed by Functional Analysis of a Yeast DNA-Binding Protein

1988 • 284 citations

Telomeres, telomerase and senescence

1990 • 260 citations

Effects of Genomic Position on the Expression of Transduced Copies of the white Gene of Drosophila

1985 • 253 citations

Addition of telomere-associated HeT DNA sequences “heals” broken chromosome ends in Drosophila

1990 • 245 citations

Monovalent cation induced structural transitions in telomeric DNAs: G-DNA folding intermediates

1991 • 245 citations

Telomerase is processive.

1991 • 238 citations

Recognition of a chromosome truncation site associated with α-thalassaemia by human telomerase

1991 • 205 citations

Developmentally programmed healing of chromosomes by telomerase in tetrahymena

1991 • 204 citations

RAP-1 factor is necessary for DNA loop formation in vitro at the silent mating type locus HML

1989 • 184 citations

A yeast Telomere Binding Activity binds to two related telomere sequence motifs and is indistinguishable from RAPT

1989 • 178 citations

Telomerase primer specificity and chromosome healing

1991 • 174 citations

Telomere terminal transferase activity in the hypotrichous ciliateOxytricha novaand a model for replication of the ends of linear DNA molecules

1988 • 171 citations

Recombination occurs during telomere formation in yeast

1989 • 169 citations

Stable length polymorphism of up to 260 kb at the tip of the short arm of human chromosome 16

1991 • 165 citations

Connections between transcriptional activators, silencers, and telomeres as revealed by functional analysis of a yeast DNA-binding protein.

1988 • 157 citations

Cloning and expression of genes for the Oxytricha telomere-binding protein: Specific subunit interactions in the telomeric complex

1991 • 151 citations

Viable deletions of a telomere from a Drosophila chromosome

1989 • 151 citations

Telomere telomere recombination provides an express pathway for telomere acquisition

1990 • 146 citations

Chromosome ends in Drosophila without telomeric DNA sequences.

1990 • 139 citations

Telomeres: structure and synthesis.

1990 • 137 citations

High-mobility group protein HMG-I localizes to G/Q- and C-bands of human and mouse chromosomes.

1989 • 137 citations

Dynamics of telomere length variation in tetrahymena thermophila

1987 • 130 citations

The in vitro DNA-binding properties of purified nuclear lamin proteins and vimentin.

1990 • 128 citations

Telomere terminal transferase activity from Euplotes crassus adds large numbers of TTTTGGGG repeats onto telomeric primers.

1989 • 118 citations

Effect of monovalent cation-induced telomeric DNA structure on the binding of Oxytricha telomeric protein

1990 • 113 citations

G-DNA: a twice-folded DNA structure adopted by single-stranded oligo(dG) and its implications for telomeres.

1990 • 110 citations

Telomere structure in Euplotes crassus: characterization of DNA-protein interactions and isolation of a telomere-binding protein.

1990 • 108 citations

Temporal and spatial coordination of chromosome movement, spindle formation, and nuclear envelope breakdown during prometaphase in Drosophila melanogaster embryos.

1990 • 103 citations

Chlamydomonas telomere sequences are A+T-rich but contain three consecutive G-C base pairs.

1990 • 99 citations

Properties of the telomeric DNA-binding protein from Oxytricha nova

1989 • 96 citations

Telomeres

1991 • 93 citations

Telomeres and Their Synthesis

1990 • 93 citations

A yeast protein that binds to vertebrate telomeres and conserved yeast telomeric junctions.

1991 • 80 citations

Two versions of the gene encoding the 41-kilodalton subunit of the telomere binding protein of Oxytricha nova.

1990 • 66 citations

Assembly and self-association of Oxytricha telomeric nucleoprotein complexes

1989 • 58 citations

How does the end begin?

1990 • 57 citations

Oxytrichatelomeric nucleoprotein complexes reconstituted with synthetic DNA

1989 • 50 citations

Mutations affecting cell division in Tetrahymena pyriformis, syngen 1

1977 • 50 citations

Characterization of a Telomere-Binding Protein from Physarum polycephalum

1991 • 38 citations

The coherence of synthetic telomeres

1991 • 34 citations

A G4-DNA/B-DNA junction at codon 12 of c-Ha-ras is actively and asymmetrically methylated by DNA (cytosine-5)methyltransferase

1989 • 26 citations

The Structures of Telomeric DNA

1991 • 25 citations

Replication origins, factors and attachment sites

1991 • 24 citations

The characterisation of 1SF monomer nucleosomes from hen oviduct and the partial characterisation of a third HMG14/17-like protein in such nucleosomes

1981 • 24 citations

Characterization of a telomere-binding protein from Physarum polycephalum.

1991 • 21 citations