Developmentally programmed healing of chromosomes by telomerase in tetrahymena

Structure and function of telomeres

1991 • 3,524 citations

Identification of a specific telomere terminal transferase activity in tetrahymena extracts

1985 • 3,331 citations

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

1989 • 1,607 citations

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

1989 • 1,509 citations

The telomere terminal transferase of tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

1987 • 1,127 citations

In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs

1990 • 632 citations

Cloning yeast telomeres on linear plasmid vectors

1982 • 625 citations

DNA sequences of telomeres maintained in yeast

1984 • 552 citations

Functional Evidence for an RNA Template in Telomerase

1990 • 392 citations

Recognition and elongation of telomeres by telomerase

1989 • 241 citations

The Molecular Biology of Ciliated Protozoa

1986 • 240 citations

Telomerase is processive.

1991 • 238 citations

Telomere terminal transferase activity in the hypotrichous ciliateOxytricha novaand a model for replication of the ends of linear DNA molecules

1988 • 171 citations

Generation of telomere-length heterogeneity in Saccharomyces cerevisiae.

1988 • 170 citations

Cloning of human telomeres by complementation in yeast

1989 • 162 citations

Cloning human telomeric DNA fragments into Saccharomyces cerevisiae using a yeast-artificial-chromosome vector.

1989 • 150 citations

Molecular cloning of human telomeres in yeast

1989 • 147 citations

Internal sequences are eliminated from genes during macronuclear development in the ciliated protozoan oxytricha nova

1984 • 140 citations

Developmentally controlled telomere addition in wild-type and mutant paramecia.

1988 • 124 citations

Telomere terminal transferase activity from Euplotes crassus adds large numbers of TTTTGGGG repeats onto telomeric primers.

1989 • 118 citations

Control of rDNA replication in Tetrahymena involves a cis-acting upstream repeat of a promoter element

1986 • 117 citations

Identification of a telomeric DNA sequence in Plasmodium berghei.

1985 • 113 citations

Ciliate Conjugation

1986 • 111 citations

An irregular satellite sequence is found at the termini of the linear extrachromosomal rDNA in Dictyostelium discoideum

1981 • 107 citations

A conserved nucleotide sequence at the sites of developmentally regulated chromosomal breakage in tetrahymena

1987 • 105 citations

Pseudo-templated transcription in prokaryotic and eukaryotic organisms.

1991 • 104 citations

Two separate regions of the extrachromosomal ribosomal deoxyribonucleic acid of Tetrahymena thermophila enable autonomous replication of plasmids in Saccharomyces cerevisiae.

1981 • 95 citations

Sequencing of Saccharomyces telomeres cloned using T4 DNA polymerase reveals two domains.

1990 • 94 citations

Telomeres and Their Synthesis

1990 • 93 citations

Non-nucleosomal packaging of a tandemly repeated DNA sequence at termini of extrachromosomal DNA coding for rRNA in Tetrahymena.

1981 • 88 citations

Tandemly repeated hexanucleotide at tetrahymena rDNA free end is generated from a single copy during development

1982 • 79 citations

Isolation and characterization of a human telomere

1989 • 78 citations

Characterization of chromosome fragmentation in two protozoans and identification of a candidate fragmentation sequence in Euplotes crassus.

1989 • 77 citations

Telomeric site position heterogeneity in macronuclear DNA ofParamecium primaurelia

1987 • 72 citations

Genetic Organization of Tetrahymena

1986 • 67 citations

Chromatin structure of the telomeric region and 3'-nontranscribed spacer of Tetrahymena ribosomal RNA genes.

1986 • 64 citations

Multiple Sequence Versions of the Oxytricha fallax 81‐MAC Alternate Processing Family1

1987 • 53 citations

Transformation of Tetrahymena thermophila with a mutated circular ribosomal DNA plasmid vector.

1989 • 49 citations

The Nuclear DNAs of Holotrichous Ciliates

1986 • 46 citations

S1 nuclease sensitivity of a double-stranded telomeric DNA sequence

1987 • 34 citations

Developmentally regulated telomere addition inTetrahymena thermophila

1988 • 27 citations

A temperature-sensitive mutation affecting cilia regeneration, nuclear development, and the cell cycle of Tetrahymena thermophila is rescued by cytoplasmic exchange.

1988 • 23 citations

Conservation of sequences adjacent to the telomeric C₄A₂repeats of ciliate macronuclear ribosomal RNA gene molecules

1986 • 20 citations

Sequence characterization ofTetrahymenamacronuclear DNA ends

1986 • 17 citations