Soy intake and cancer risk: A review of thein vitroandin vivodata

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

1987 • 3,773 citations

Genistein, daidzein, and their .beta.-glycoside conjugates: antitumor isoflavones in soybean foods from American and Asian diets

1993 • 881 citations

Dietary effects on breast-cancer risk in Singapore

1991 • 782 citations

Genistein, a dietary-derived inhibitor of in vitro angiogenesis.

1993 • 777 citations

Western diet and Western diseases: Some hormonal and biochemical mechanisms and associations

1990 • 691 citations

Nonsteroidal estrogens of dietary origin: possible roles in hormone-dependent disease

1984 • 628 citations

A prospective study of demographics, diet, and prostate cancer among men of Japanese ancestry in Hawaii.

1989 • 628 citations

Phytoestrogen Interaction with Estrogen Receptors in Human Breast Cancer Cells*

1978 • 605 citations

The Role of Soy Products in Reducing Risk of Cancer

1991 • 600 citations

Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II.

1989 • 559 citations

Large-Bowel Cancer in Hawaiian Japanese2

1973 • 492 citations

Relationship of Animal Protein-Rich Diet to Kidney Stone Formation and Calcium Metabolism*

1988 • 472 citations

Genistein inhibition of the growth of human breast cancer cells: Independence from estrogen receptors and the multi-drug resistance gene

1991 • 467 citations

Effect of genistein on topoisomerase activity and on the growth of [VAL 12]Ha-ras-transformed NIH 3T3 cells

1988 • 443 citations

Genistein and biochanin A inhibit the growth of human prostate cancer cells but not epidermal growth factor receptor tyrosine autophosphorylation

1993 • 423 citations

[30] Use and specificity of genistein as inhibitor of protein-tyrosine kinases

1991 • 421 citations

STEROID AND PHYTO-OESTROGEN BINDING TO SHEEP UTERINE RECEPTORS IN VITRO

1972 • 390 citations

Stomach Cancer Among Japanese in Hawaii<xref ref-type="fn" rid="FN2">2</xref>

1972 • 388 citations

Experimental evidence of dietary factors and hormone-dependent cancers.

1975 • 379 citations

Inhibition of tumor Promoter‐induced hydrogen peroxide formationin vitroandin vivoby genistein

1993 • 366 citations

Diet and Cancer of the Colon and Rectum: A Case-Control Study

1986 • 351 citations

In vitro bioassays of non-steroidal phytoestrogens

1993 • 342 citations

Lung cancer among women in north-east China

1990 • 325 citations

Dietary habits and gastro-intestinal cancers : a comparative case-control study of stomach and large intestinal cancers in Nagoya, Japan

1986 • 322 citations

Western diet and Western diseases: Some hormonal and biochemical mechanisms and associations

1990 • 301 citations

Diet and high risk of stomach cancer in Shandong, China

1990 • 280 citations

Review of clinical studies on cholesterol-lowering response to soy protein

1991 • 268 citations

Soybeans inhibit mammary tumors in models of breast cancer.

1990 • 248 citations

Nuclear Binding and Retention of the Receptor Estrogen Complex: Relation to the Agonistic and Antagonistic Properties of Estriol1¹

1977 • 245 citations

Mutagens and Carcinogens in the Diet

1991 • 239 citations

Mechanisms of action in NIH-3T3 cells of genistein, an inhibitor of EGF receptor tyrosine kinase activity

1990 • 235 citations

Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by genistein.

1990 • 229 citations

A prospective study of stomach cancer and its relation to diet, cigarettes, and alcohol consumption.

1990 • 211 citations

DIET AND CANCER OF THE STOMACH: A CASE‐CONTROL STUDY IN GREECE

1985 • 210 citations

Diet, nutrition, and cancer

1985 • 209 citations

Liver cancer in Thailand. I. A case‐control study of cholangiocarcinoma

1991 • 190 citations

Dietary factors in colon cancer: International relationships

1985 • 187 citations

Dietary habits and lung cancer risk among Chinese females in Hong Kong who never smoked

1988 • 180 citations

Genistein is an effective stimulator of sex hormone-binding globulin production in hepatocarcinoma human liver cancer cells and suppresses proliferation of these cells in culture

1993 • 163 citations

Validation of two in vitro test systems for estrogenic activities with zearalenone, phytoestrogens and cereal extracts

1992 • 149 citations

Epidemiology of prostate cancer with special reference to the role of diet.

1979 • 148 citations

Diet and Cancer of the Colon and Rectum: A Case-Control Study in China

1991 • 147 citations

Tyrosine Phosphorylation of Phospholipase C-II in Vitro by the Epidermal Growth Factor Receptor

1989 • 145 citations

A large scale cohort study on cancer risks by diet--with special reference to the risk reducing effects of green-yellow vegetable consumption.

1985 • 144 citations

Breast cancer and diet among the Japanese in Hawaii

1978 • 142 citations

Soybean diet lowers breast tumor incidence in irradiated rats

1980 • 141 citations

Phytoestrogen content of processed soybean products

1982 • 140 citations

THE INTERACTION IN THE IMMATURE MOUSE OF POTENT OESTROGENS WITH COUMESTROL, GENISTEIN AND OTHER UTERO-VAGINOTROPHIC COMPOUNDS OF LOW POTENCY

1966 • 139 citations

A case-control study of stomach cancer and its relation to diet, cigarettes, and alcohol consumption in Saitama Prefecture, Japan

1992 • 133 citations

Interaction between the epidermal growth factor receptor and phosphoinositide kinases.

1991 • 130 citations

Effect of a Diet With High Levels of Protein and Fat on Colon Carcinogenesis in F344 Rats Treated With 1,2-Dimethylhydrazine2

1976 • 124 citations

Occurrence of breast cancer in relation to diet and reproductive history: a case-control study in Fukuoka, Japan.

1985 • 123 citations

Diet and cancer of the stomach: A case‐control study in China

1988 • 121 citations

Flavonoids: biochemical effects and therapeutic applications

1992 • 115 citations

Affinity of Phytoestrogens for Estradiol-Binding Proteins and Effect of Coumestrol on Growth of 7,12-Dimethylbenz[a]anthracene-Induced Rat Mammary Tumors23

1980 • 115 citations

AN EPIDEMIOLOGICAL STUDY ON CANCER IN JAPAN

1957 • 113 citations

Soy of dietary source plays a preventive role against the pathogenesis of prostatitis in rats

1992 • 107 citations

Oestrogenic potency of genistin and daidzin in mice

1985 • 106 citations

Epidemiology of Pancreatic Cancer in Japan

1989 • 102 citations

Modulation of Age-Related Hyperparathyroidism and Senile Bone Loss in Fischer Rats by Soy Protein and Food Restriction*

1988 • 102 citations

Dietary Soybean Isolate and Methionine Supplementation Affect Mammary Tumor Progression in Rats

1991 • 94 citations

Liver cancer in Thailand. II. A case‐control study of hepatocellular carcinoma

1991 • 92 citations

A Case‐Control Study of Prostatic Cancer With Reference to Dietary Habits

1988 • 89 citations

Dietary determinants of lung‐cancer risk: Results from a case‐control study in Yunnan province, China

1992 • 88 citations

A Case‐Control Study of Biliary Tract Cancer in Niigata Prefecture, Japan

1989 • 87 citations

Proliferation of human myeloid leukemia cell line associated with the tyrosine-phosphorylation and activation of the proto-oncogene c-kit product

1991 • 87 citations

Induction of in vitro differentiation of mouse erythroleukemia cells by genistein, an inhibitor of tyrosine protein kinases.

1991 • 80 citations

Relationship of soybean paste soup intake to gastric cancer risk

1981 • 80 citations

A Sensitive Bioassay for Detection of Dietary Estrogens in Animal Feeds

1990 • 71 citations

BINDING OF PHYTO-OESTROGEN AND OESTRADIOL-17β BY CYTOPLASMIC RECEPTORS IN THE PITUITARY GLAND AND HYPOTHALAMUS OF THE EWE

1980 • 70 citations

Proliferation of human myeloid leukemia cell line associated with the tyrosine-phosphorylation and activation of the proto-oncogene c-kit product

1991 • 66 citations

Life-style and cancer: from epidemiological evidence to public behavior change to mortality reduction of target cancers.

1992 • 65 citations

Fundamental Differences in the Action of Estrogens and Antiestrogens on the Uterus: Comparison Between Compounds with Similar Duration of Action¹²

1977 • 63 citations

Synthesis and biological evaluation of a series of flavones designed as inhibitors of protein tyrosine kinases.

1992 • 62 citations

Inhibition of abl Oncogene Tyrosine Kinase Induces Erythroid Differentiation of Human Myelogenous Leukemia K562 Cells

1990 • 62 citations

EFFECT OF NORETHISTERONE ACETATE, DIMETHYLSTILBOESTROL, GENISTEIN AND COUMESTROL ON UPTAKE OF [3H]OESTRADIOL BY UTERUS, VAGINA AND SKELETAL MUSCLE OF IMMATURE MICE

1969 • 59 citations

Epidemiology of Stomach Cancer in Japan With Special Reference to the Strategy for the Primary Prevention

1984 • 58 citations

Development and application of a high‐performance liquid chromatographic method for the analysis of phytoestrogens

1989 • 57 citations

Effect of miso (Japanese soybean paste) and NaCl on dmba‐induced rat mammary tumors

1990 • 57 citations

Tyrosine phosphorylation by the epidermal growth factor receptor kinase induces functional alterations in microtubule-associated protein 2.

1987 • 57 citations

Inhibition of spontaneous hepatocarcinogenesis in C3H/HeN mice by Edi Pro A, an isolated soy protein

1981 • 56 citations

Effects of inhibitors of protein tyrosine kinase activity and/or phosphatidylinositol turnover on differentiation of some human myelomonocytic leukemia cells

1991 • 54 citations

Anti-nutritional effects of soyabean: a review.

1989 • 54 citations

Induction of in vitro differentiation of mouse embryonal carcinoma (F9) cells by inhibitors of topoisomerases.

1991 • 52 citations

Inhibitors for protein-tyrosine kinases, ST638 and genistein, induce differentiation of mouse erythroleukemia cells in a synergistic Manner

1989 • 50 citations

Co-carcinogenic effects of several Korean foods on gastric cancer induced by N-methyl-N′-nitro-N-nitrosoguanidine in rats

1985 • 47 citations

Effect of soybean feeding on experimental carcinogenesis—III. Carcinogenecity of nitrite and dibutylamine in mice: a histopathological study

1988 • 47 citations

A Case‐Control Study of Single and Multiple Stomach Cancers in Saitama Prefecture, Japan

1992 • 47 citations

Relationship of diet to the incidence of esophageal and stomach cancer in Japan

1981 • 38 citations

Modification of spontaneous mammary tumors in mice fed different sources of protein, fat and carbohydrate

1983 • 36 citations

EFFECTS OF SOY PRODUCTS IN REDUCING RISK OF SPONTANEOUS AND NEUTRON-INDUCED LIVER-TUMORS IN MICE

1993 • 33 citations

Influence of dietary lipotrope and lipid content on aflatoxin B1, N-2-fluorenylacetamide, and 1,2-dimethylhydrazine carcinogenesis in rats.

1980 • 27 citations

Experience with 1,079 cases of cancer of the stomach seen in Korea from 1962 to 1968

1970 • 24 citations

Receptor interconversion model of hormone action. 2. Requirement of both kinase and phosphatase activities for conferring estrogen binding activity to the estrogen receptor

1990 • 22 citations

1,2-dimethylhydrazine induced intestinal cancer in rats fed beef or soybean protein

1979 • 20 citations

INTERACTION OF GENISTEIN WITH OESTRADIOL IN THE REPRODUCTIVE TRACT OF THE OVARIECTOMIZED MOUSE

1967 • 20 citations

Effects of soyabean and ascorbic acid on experimental carcinogenesis

1989 • 17 citations

The Effects of Sodium Chloride, Miso or Ethanol on Development of Intestinal Metaplasia after X‐Irradiation of the Rat Glandular Stomach

1992 • 16 citations

Protease Action in Carcinogenesis

1979 • 16 citations

Action of phyto-estrogens coumestrol and genistein on cytosolic and nuclear oestradiol-17β receptors in immature rat uterus

1980 • 15 citations

日本の大腸がんに関する疫学的考察 ＩＩ 直腸がん・結腸がんの背景因子に関する症例・対照研究:(2) 直腸癌•結腸癌の背景因子に関する症例•対照研究

1984 • 14 citations

UTERINE WEIGHT CHANGES AND ³H-URIDINE UPTAKE IN RATS TREATED WITH PHYTOESTROGENS

1980 • 11 citations

Specificities in the synthesis of a cytoplasmic estrogen-induced uterine protein

1976 • 8 citations

Contribution of dietary habits to esophageal cancer in Japan.

1990 • 6 citations

EPIDEMIOLOGY OF GASTRIC CANCER IN CHINA

1990 • 3 citations

Dietary Pattern and Soybean Processing in Japan Today

1983 • 2 citations

[Analysis of etiological factors in gastric cancer in Fuzhou City].

1986 • 2 citations