Pathogenesis of Venous Thromboembolism: When the Cup Runneth Over
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Abstract
References (118)
Mutation in blood coagulation factor V associated with resistance to activated protein C
1994 • 3,871 citations
A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis
1996 • 3,124 citations
Trends in the Incidence of Deep Vein Thrombosis and Pulmonary Embolism
1998 • 2,620 citations
Risk Factors for Deep Vein Thrombosis and Pulmonary Embolism
2000 • 2,118 citations
Malignancies, Prothrombotic Mutations, and the Risk of Venous Thrombosis
2005 • 1,798 citations
Recurrent venous thromboembolism and bleeding complications during anticoagulant treatment in patients with cancer and venous thrombosis
2002 • 1,784 citations
Prognosis of Cancers Associated with Venous Thromboembolism
2000 • 1,581 citations
A Randomized Clinical Trial Evaluating Tamoxifen in the Treatment of Patients with Node-Negative Breast Cancer Who Have Estrogen-Receptor–Positive Tumors
1989 • 1,471 citations
Venous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE study): a multinational cross-sectional study
2008 • 1,457 citations
Deficiency of protein C in congenital thrombotic disease.
1981 • 1,260 citations
World distribution of factor V Leiden
1995 • 1,184 citations
High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance) [see comments]
1995 • 1,036 citations
Cardiovascular Risk Factors and Venous Thromboembolism
2007 • 891 citations
Rates of Initial and Recurrent Thromboembolic Disease Among Patients with Malignancy Versus Those without Malignancy: Risk Analysis Using Medicare Claims Data
1999 • 890 citations
Deep vein thrombosis and pulmonary embolism in two cohorts: the longitudinal investigation of thromboembolism etiology
2004 • 844 citations
Genetic Susceptibility to Venous Thrombosis
2001 • 827 citations
Venous Thromboembolism, Thrombophilia, Antithrombotic Therapy, and Pregnancy
2008 • 822 citations
Risk of idiopathic cardiovascular death and rionfatal venous thromboembolism in women using oral contraceptives with differing progestagen components
1995 • 747 citations
Incidence of Recurrent Thromboembolic and Bleeding Complications Among Patients With Venous Thromboembolism in Relation to Both Malignancy and Achieved International Normalized Ratio: A Retrospective Analysis
2000 • 733 citations
Geographic Distribution of the 20210 G to A Prothrombin Variant
1998 • 707 citations
Prevention of Venous Thromboembolism in General Surgical Patients
1988 • 696 citations
Epidemiology and Risk Factors for Venous Thrombosis
2007 • 691 citations
Pregnancy, the postpartum period and prothrombotic defects: risk of venous thrombosis in the MEGA study
2008 • 686 citations
An Epidemiologic Study of Risk Factors for Deep Vein Thrombosis in Medical Outpatients
2000 • 680 citations
Third generation oral contraceptives and risk of venous thromboembolic disorders: an international case-control study
1996 • 597 citations
Incidence of symptomatic venous thromboembolism after different elective or urgent surgical procedures
2003 • 579 citations
Hormone replacement therapy and risk of venous thromboembolism in postmenopausal women: systematic review and meta-analysis
2008 • 522 citations
Recurrent Venous Thromboembolism in Patients with a Partial Deficiency of Protein S
1984 • 507 citations
Prothrombin and Factor V Mutations in Women with a History of Thrombosis during Pregnancy and the Puerperium
2000 • 495 citations
Third generation oral contraceptives and risk of venous thrombosis: meta-analysis
2001 • 461 citations
Obesity: risk of venous thrombosis and the interaction with coagulation factor levels and oral contraceptive use
2003 • 438 citations
Inherited thrombophilia: pathogenesis, clinical syndromes, and management [see comments]
1996 • 438 citations
Risk Factors for Pregnancy Associated Venous Thromboembolism
1997 • 427 citations
Venous thromboembolic disease and combined oral contraceptives: results of international multicentre case-control study. World Health Organization Collaborative Study of Cardiovascular Disease and Steroid Hormone Contraception.
1995 • 409 citations
Hyperhomocysteinemia and Venous Thrombosis: A Meta-analysis
1998 • 371 citations
Inherited resistance to activated protein C iscorrected by anticoagulant cofactor activity found to be a property of factorV.
1994 • 359 citations
Incidence of Venous Thromboembolism in Families with Inherited Thrombophilia
1999 • 322 citations
Risk of Venous Thromboembolic Disease Associated With Hormonal Contraceptives and Hormone Replacement Therapy
2004 • 300 citations
Thrombosis of the Deep Leg Veins Due to Prolonged Sitting
1954 • 297 citations
Factor V Cambridge: A New Mutation (Arg306→Thr) Associated With Resistance to Activated Protein C
1998 • 281 citations
Trends in the Incidence of Deep Vein Thrombosis and Pulmonary Embolism: A 35-Year Population-Based Study.
2006 • 276 citations
Genetic risk factors of venous thrombosis
2001 • 275 citations
Increased thromboembolic complications with concurrent tamoxifen and chemotherapy in a randomized trial of adjuvant therapy for women with breast cancer. National Cancer Institute of Canada Clinical Trials Group Breast Cancer Site Group.
1996 • 274 citations
Congenital Thrombophilic States Associated with Venous Thrombosis: A Qualitative Overview and Proposed Classification System
2003 • 272 citations
Predictors of Rehospitalization for Symptomatic Venous Thromboembolism after Total Hip Arthroplasty
2000 • 261 citations
AIR TRAVEL AND THROMBOTIC EPISODES: THE ECONOMY CLASS SYNDROME
1988 • 219 citations
A Factor V Genetic Component Differing From Factor V R506Q Contributes to the Activated Protein C Resistance Phenotype
1997 • 213 citations
A Novel Mutation of Arg306 of Factor V Gene in Hong Kong Chinese
1998 • 210 citations
Venous Thrombosis: The Role of Genes, Environment, and Behavior
2005 • 197 citations
Inherited Thrombophilia and First Venous Thromboembolism during Pregnancy and Puerperium
2002 • 194 citations
Thromboembolic complications of cancer: Epidemiology, pathogenesis, diagnosis, and treatment
2002 • 188 citations
Meta-analysis of the risk of venous thrombosis in individuals with antiphospholipid antibodies without underlying autoimmune disease or previous thrombosis
1998 • 186 citations
Association between hormone replacement therapy and subsequent arterial and venous vascular events: a meta-analysis
2008 • 186 citations
The Thrombophilic State Induced by Therapeutic Agents in the Cancer Patient
1999 • 184 citations
SHELTER DEATHS FROM PULMONARY EMBOLISM
1940 • 183 citations
Pathogenesis of Venous Thrombosis
1992 • 173 citations
High Prevalence of Detectable Deep Venous Thrombosis in Patients With Acute Pulmonary Embolism
1999 • 169 citations
Sticky Platelet Syndrome
1999 • 152 citations
Protein S Deficiency: A Database of Mutations – Summary of the First Update
2000 • 147 citations
Epidemiology and Risk Factors of Venous Thromboembolism
2006 • 138 citations
Treatment of menopausal symptoms: what shall we do now?
2005 • 133 citations
Activation of Purified Prothrombin to Autoprothrombin I or Autoprothrombin II (Platelet Cofactor II or Autoprothrombin II-A)
1961 • 131 citations
Travel and venous thrombosis: a systematic review
2007 • 128 citations
Pulmonary embolism and stroke in relation to pregnancy: How can high-risk women be identified?
2002 • 123 citations
Minor Injuries as a Risk Factor for Venous Thrombosis
2008 • 122 citations
Antithrombin: Its Physiological Importance and Role in DIC
1998 • 120 citations
Prevention of venous thromboembolism in patients with immobilization of the lower extremities: a meta‐analysis of randomized controlled trials
2008 • 109 citations
Venous Thrombosis: The Role of Genes, Environment, and Behavior
2005 • 108 citations
Deep Venous Thrombosis After Knee Arthroscopy: A Meta-analysis
2005 • 104 citations
Double Trouble for 2,609 Hospitalized Medical Patients Who Developed Deep Vein Thrombosis
2007 • 98 citations
Malignancies, prothrombotic mutations, and the risk of venous thrombosis
2005 • 97 citations
Effect of raloxifene therapy on venous thromboembolism in postmenopausal women: A meta-analysis
2008 • 96 citations
Cancer and Venous Thromboembolism: Scope of the Problem
2005 • 93 citations
Inherited Thrombophilic Risk Factors and Venous Thromboembolism
2000 • 90 citations
Lipoprotein (a) and Venous Thromboembolism in Adults: A Meta-Analysis
2007 • 85 citations
Interpretations. Cardiovascular disease and combined oral contraceptives: reviewing the evidence and balancing the risks
1999 • 84 citations
Premature ovarian failure: a review
2007 • 83 citations
Prevalence of deep vein thrombosis in suspected and proven pulmonary embolism: a meta-analysis.
1998 • 82 citations
Venous thromboembolism and cancer: a two-way clinical association.
1997 • 79 citations
Protein S deficiency: a database of mutations. For the Plasma Coagulation Inhibitors Subcommittee of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis.
1997 • 78 citations
Hyperhomocysteinemia and Venous Thromboembolism
2006 • 74 citations
Antiphospholipid Syndrome and Thrombosis
1999 • 70 citations
Venous Thromboembolism: A Review of Risk and Prevention in Colorectal Surgery Patients
2006 • 70 citations
Effect of hemostatic risk factors on the individual probability of thrombosis during pregnancy and the puerperium
2003 • 67 citations
Pathogenesis, clinical and laboratory aspects of thrombosis in cancer
2007 • 64 citations
Changes in hemostasis activity during delivery and theimmediate postpartum period
1990 • 61 citations
Thromboembolism in Plastic Surgery
2005 • 59 citations
Protein S deficiency.
1997 • 58 citations
The inherited thrombophilias: genetics, epidemiology, and laboratory evaluation
2003 • 57 citations
Cancer and venous thromboembolism
2005 • 51 citations
Antiphospholipid Syndrome: Clinical and Diagnostic Utility of Laboratory Tests
2005 • 51 citations
Risk of idiopathic cardiovascular death and nonfatal venous thromboembolism in women using oral contraceptives with differing progestagen components
1996 • 51 citations
Cancer and Venous Thromboembolism
2006 • 46 citations
Sticky platelet syndrome and thrombocythemia
2003 • 46 citations
Travel and the risk of symptomatic venous thromboembolism
2003 • 44 citations
Genetic Risk Factors for Venous Thrombosis
2000 • 43 citations
Travel, Venous Thromboembolism, and Thrombophilia
2005 • 37 citations
The molecular genetics of familial venous thrombosis
1999 • 36 citations
Venous thromboembolism and cancer A two-way clinical association
1997 • 35 citations
Prevention of Venous Thromboembolism in General, Surgical Patients: Results of a Meta-Analysis
1989 • 35 citations
Venous Thromboembolism in Cosmetic Plastic Surgery: Maximizing Patient Safety
2003 • 34 citations
Pathogenesis of venous thrombosis
1992 • 29 citations
ORAL CONTRACEPTIVE PILLS AND HORMONAL REPLACEMENT THERAPY AND THROMBOEMBOLIC DISEASE
2000 • 27 citations
Do Thrombophilias Cause Placenta-Mediated Pregnancy Complications?
2007 • 26 citations
Clinical relevance of antithrombin deficiencies.
1995 • 25 citations
Enhanced platelet aggregation with TRAP-6 and collagen in platelet aggregometry in patients with venous thromboembolism
2002 • 23 citations
Thrombophilia and Fetal Loss
2003 • 23 citations
A Factor V Genetic Component Differing From Factor V R506Q Contributes to the Activated Protein C Resistance Phenotype
1997 • 22 citations
Thrombophilia in pregnancy.
2002 • 17 citations
Thromboembolic Complications Related to Central Venous Access Catheters in Cancer Patients
2007 • 15 citations
Prophylaxis of Venous Thromboembolism Following Orthopedic Surgery: Mechanical and Pharmacological Approaches and the Need for Extended Prophylaxis
1999 • 11 citations
Venous thromboembolism and hormonal contraception
2016 • 10 citations
Prothrombotic effects and clinical implications of third-generation oral contraceptives use
2002 • 8 citations
Venous Thromboembolism in Cancer Patients: Expanding Horizons
2002 • 8 citations
Diagnosis and management of inherited and acquired thrombophilias.
1999 • 7 citations
Severe preeclampsia in antithrombin III deficiency with no history of venous thromboembolism.
2001 • 7 citations
Sex Hormones and Thrombosis
2007 • 3 citations
Risque thromboembolique veineux au cours des affections médicales aiguës. Partie 2 : situations à risque en milieu ambulatoire, en milieu médical hospitalier et en médecine interne
2008 • 3 citations