The N terminus of the Drosophila Numb protein directs membrane association and actin-dependent asymmetric localization

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

The development of Drosophila melanogaster

1994 • 3,057 citations

Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryos

1991 • 1,103 citations

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

1994 • 749 citations

Latrunculins: Novel Marine Toxins That Disrupt Microfilament Organization in Cultured Cells

1983 • 736 citations

High Rates of Actin Filament Turnover in Budding Yeast and Roles for Actin in Establishment and Maintenance of Cell Polarity Revealed Using the Actin Inhibitor Latrunculin-A

1997 • 734 citations

Control of Daughter Cell Fates during Asymmetric Division: Interaction of Numb and Notch

1996 • 656 citations

A modular set of lacZ fusion vectors for studying gene expression in Caenorhabditis elegans

1990 • 618 citations

Latrunculins—novel marine macrolides that disrupt microfilament organization and affect cell growth: I. Comparison with cytochalasin D

1989 • 566 citations

Mitotic domains reveal early commitment of cells in Drosophila embryos

1989 • 554 citations

Generation of asymmetry and segregation of germ-line granules in early C. elegans embryos

1983 • 534 citations

Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question

1992 • 527 citations

Mating Type Switching in Yeast Controlled by Asymmetric Localization of ASH1 mRNA

1997 • 493 citations

numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos

1989 • 493 citations

Asymmetric segregation of Numb and Prospero during cell division

1995 • 489 citations

The prospero gene specifies cell fates in the drosophila central nervous system

1991 • 442 citations

Numb Antagonizes Notch Signaling to Specify Sibling Neuron Cell Fates

1996 • 415 citations

Mitotic domains reveal early commitment of cells in Drosophila embryos

1989 • 412 citations

Role of inscuteable in orienting asymmetric cell divisions in Drosophila

1996 • 389 citations

Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast

1997 • 386 citations

Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation.

1985 • 386 citations

Development of adult sensilla on the wing and notum of Drosophila melanogaster

1989 • 383 citations

prospero is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in Drosophila

1991 • 360 citations

Asymmetric Accumulation of Ash1p in Postanaphase Nuclei Depends on a Myosin and Restricts Yeast Mating-Type Switching to Mother Cells

1996 • 355 citations

The PROSPERO transcription factor is asymmetrically localized to the cell cortex during neuroblast mitosis in Drosophila

1996 • 333 citations

Asymmetric segregation of the homeodomain protein Prospero duringDrosophila development

1995 • 330 citations

The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage.

1996 • 313 citations

Identification of an Asymmetrically Localized Determinant, Ash1p, Required for Lineage-Specific Transcription of the Yeast HO Gene

1996 • 278 citations

A non-muscle myosin required for embryonic polarity in Caenorhabditis elegans

1996 • 262 citations

Asymmetric localization of numb autonomously determines sibling neuron identity in the Drosophila CNS

1995 • 249 citations

Neurogenesis of the peripheral nervous system in Drosophila embryos: DNA replication patterns and cell lineages

1989 • 248 citations

inscuteable,A Neural Precursor Gene ofDrosophila,Encodes a Candidate for a Cytoskeleton Adaptor Protein

1996 • 174 citations

Only a subset of the binary cell fate decisions mediated by Numb/Notch signaling in Drosophila sensory organ lineage requires Suppressor of Hairless

1997 • 90 citations

Mechanisms of asymmetric cell division during animal development

1997 • 86 citations

A method to stain nuclei of Drosophila for confocal microscopy.

1994 • 26 citations