Glutamate neurotoxicity in mesencephalic dopaminergic neurons in culture

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

The functional anatomy of basal ganglia disorders

1989 • 5,166 citations

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

1987 • 3,773 citations

Molecular Diversity of Glutamate Receptors and Implications for Brain Function

1992 • 2,535 citations

Optimized survival of hippocampal neurons in B27‐supplemented neurobasal™, a new serum‐free medium combination

1993 • 2,272 citations

Reversal of Experimental Parkinsonism by Lesions of the Subthalamic Nucleus

1990 • 1,875 citations

Ionic dependence of glutamate neurotoxicity

1987 • 1,811 citations

Inhibition of Postsynaptic PKC or CaMKII Blocks Induction But Not Expression of LTP

1989 • 1,335 citations

Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists

1988 • 983 citations

Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases

1989 • 905 citations

Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists

1991 • 554 citations

The current excitement in long term potentiation

1988 • 538 citations

Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors

1991 • 520 citations

Enhancement of the Glutamate Response by cAMP-Dependent Protein Kinase in Hippocampal Neurons

1991 • 486 citations

Stimulation of Protein Tyrosine Phosphorylation by NMDA Receptor Activation

1991 • 464 citations

Regulation of Kainate Receptors by cAMP-Dependent Protein Kinase and Phosphatases

1991 • 404 citations

Gangliosides prevent glutamate and kainate neurotoxicity in primary neuronal cultures of neonatal rat cerebellum and cortex.

1988 • 384 citations

Immunocytochemical localization of tubulin and microtubule-associated protein 2 during the development of hippocampal neurons in culture

1986 • 371 citations

Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices

1990 • 356 citations

Glutamate neurotoxicity in vitro: antagonist pharmacology and intracellular calcium concentrations

1990 • 343 citations

Ganglioside inhibition of glutamate-mediated protein kinase C translocation in primary cultures of cerebellar neurons.

1987 • 309 citations

The AMPA receptor antagonist NBQX has antiparkinsonian effects in monoamine‐depleted rats and MPTP‐treated monkeys

1991 • 258 citations

Activation of NMDA receptors induces rapid dephosphorylation of the cytoskeletal protein MAP2

1990 • 220 citations

Direct Evidence That Excitotoxicity in Cultured Neurons Is Mediated via N‐Methyl‐D‐Aspartate (NMDA) as well as Non‐NMDA Receptors

1989 • 208 citations

Differential Localization of MAP‐2 and Tau in Mammalian Neurons in Situa

1986 • 208 citations

The expression and distribution of the microtubule-associated proteins tau and microtubule-associated protein 2 in hippocampal neurons in the rat in situ and in cell culture

1987 • 195 citations

Presynaptic Glutamate Receptors Modulate Dopamine Release from Striatal Synaptosomes

1991 • 188 citations

Down-regulation of protein kinase C protects cerebellar granule neurons in primary culture from glutamate-induced neuronal death.

1990 • 179 citations

Excitotoxicity induced by enhanced excitatory neurotransmission in cultured hippocampal pyramidal neurons

1990 • 155 citations

Glutamate receptor subtypes mediate excitatory synaptic currents of dopamine neurons in midbrain slices

1991 • 145 citations

Glutamate-induced neuronal death in primary cultures of cerebellar granule cells: protection by synthetic derivatives of endogenous sphingolipids.

1990 • 132 citations

Evidence for the presence of N-methyl-d-aspartate receptors in the ventral tegmental area of the rat: an electrophysiological in vitro study

1990 • 103 citations

Glutamate receptors in the substantia nigra of Parkinson's disease brains

1992 • 83 citations

Pharmacologically distinct glutamate receptors on cerebellar granule cells

1986 • 79 citations

Characterization and mechanism of glutamate neurotoxicity in primary striatal cultures

1990 • 70 citations

Dual effect of glycine on NMDA-induced neurotoxicity in rat cortical cultures

1990 • 61 citations

[3H]MK-801 Binding to N-Methyl-d-Aspartate Receptors Solubilized from Rat Brain: Effects of Glycine Site Ligands, Polyamines, Ifenprodil, and Desipramine

1991 • 44 citations

Heterogeneity of N‐Methyl‐D‐Aspartate Receptors Regulating the Release of Dopamine and Acetylcholine from Striatal Slices

1991 • 39 citations

Inhibition of NMDA-induced protein kinase C translocation by a Zn2+ chelator: Implication of intracellular Zn2+

1991 • 36 citations

Extracellular pH modulates N-methyl-d-aspartate receptor-mediated neurotoxicity and calcium accumulation in rat cortical cultures

1992 • 36 citations