Dual effect of glycine on NMDA-induced neurotoxicity in rat cortical cultures

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

Glycine potentiates the NMDA response in cultured mouse brain neurons

1987 • 3,116 citations

Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones

1984 • 2,822 citations

Ionic dependence of glutamate neurotoxicity

1987 • 1,811 citations

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

1984 • 1,689 citations

Requirement for Glycine in Activation of NMDA-Receptors Expressed in Xenopus Oocytes

1988 • 1,415 citations

Glutamate neurotoxicity in cortical cell culture

1987 • 1,400 citations

Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay

1987 • 1,280 citations

Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists

1988 • 983 citations

Glutamate becomes neurotoxic via the N-methyl-d-aspartate receptor when intracellular energy levels are reduced

1988 • 972 citations

The role of divalent cations in the N‐methyl‐D‐aspartate responses of mouse central neurones in culture.

1988 • 810 citations

Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil

1987 • 647 citations

The neurotoxicity of excitatory amino acids is produced by passive chloride influx

1985 • 634 citations

Huntingtons Disease

1986 • 551 citations

7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex.

1988 • 517 citations

Delayed increase of Ca2+ influx elicited by glutamate: role in neuronal death.

1989 • 484 citations

Synaptic Activity Mediates Death of Hypoxic Neurons

1983 • 441 citations

The action of N‐methyl‐D‐aspartic acid on mouse spinal neurones in culture.

1985 • 417 citations

Gangliosides prevent glutamate and kainate neurotoxicity in primary neuronal cultures of neonatal rat cerebellum and cortex.

1988 • 384 citations

Use-dependent block of excitatory amino acid currents in cultured neurons by ketamine

1987 • 380 citations

Protective Effect of the Glutamate Antagonist, MK-801 in Focal Cerebral Ischemia in the Cat

1988 • 370 citations

N-methyl-D-aspartate receptors mediate hypoxic neuronal injury in cortical culture.

1987 • 309 citations

The role of specific ions in glutamate neurotoxicity

1986 • 298 citations

Neurons Containing NADPH-Diaphorase Are Selectively Resistant to Quinolinate Toxicity

1986 • 292 citations

A kinetic analysis of the modulation of N‐methyl‐D‐aspartic acid receptors by glycine in mouse cultured hippocampal neurones.

1990 • 216 citations

Structural requirements for activation of the glycine coagonist site of N-methyl-D-aspartate receptors expressed in Xenopus oocytes.

1989 • 159 citations

Indole-2-Carboxylic Acid: A Competitive Antagonist of Potentiation by Glycine at the NMDA Receptor

1989 • 138 citations

Heterogeneity of Glycine Receptors and Their Messenger RNAs in Rat Brain and Spinal Cord

1988 • 130 citations

Structural requirements for activation of the glycine receptor that modulates the N-methyl-D-aspartate operated ion channel

1988 • 120 citations

1‐Aminocyclopropane Carboxylic Acid: A Potent and Selective Ligand for the Glycine Modulatory Site of the N‐Methyl‐<scp>d</scp>‐Aspartate Receptor Complex

1989 • 120 citations

Ketamine protects hippocampal neurons from anoxia in vitro

1987 • 113 citations

Kinetic characterization of the phencyclidine-N-methyl-D-aspartate receptor interaction: evidence for a steric blockade of the channel

1988 • 112 citations

The excitotoxin quinolinic acid is present in the brain of several mammals and its cortical content increases during the aging process

1984 • 108 citations

Epileptic brain damage: pathophysiology and neurochemical pathology.

1986 • 103 citations

Coexpression of N-methyl-D-aspartate and phencyclidine receptors in Xenopus oocytes injected with rat brain mRNA.

1988 • 93 citations

GABAergic neocortical neurons are resistant to NMDA receptor‐mediated injury

1989 • 87 citations

Time and concentration dependency of the toxicity of excitatory amino acids on cerebral neurones in primary culture

1987 • 86 citations

Applications of quantitative measurements for assessing glutamate neurotoxicity.

1988 • 81 citations

What confers specificity on glycine for its receptor site?

1989 • 71 citations

GABAergic neurons in rat hippocampal culture

1986 • 39 citations

Voltage-dependent block by strychnine of N-methyl-D-aspartic acid-activated cationic channels in rat cortical neurons in culture.

1988 • 39 citations