Engineered Biosynthesis of Structurally Diverse Tetraketides by a Trimodular Polyketide Synthase

Modular Organization of Genes Required for Complex Polyketide Biosynthesis

1991 • 883 citations

An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea

1990 • 611 citations

Engineered Biosynthesis of Novel Polyketides

1993 • 459 citations

Crystal Structure of a Purple Acid Phosphatase Containing a Dinuclear Fe(III)-Zn(II) Active Site

1995 • 428 citations

Bidirectional incompatibility between conspecific populations of Drosophila simulans

1990 • 404 citations

Direct, regiospecific 2-lithiation of pyridines and pyridine 1-oxides with in situ electrophilic trapping

1983 • 402 citations

Binding to DNA and the Retinoblastoma Gene Product Promoted by Complex Formation of Different E2F Family Members

1993 • 271 citations

Repositioning of a Domain in a Modular Polyketide Synthase to Promote Specific Chain Cleavage

1995 • 250 citations

An erythromycin analog produced by reprogramming of polyketide synthesis.

1993 • 183 citations

A remarkable steric effect in palladium-catalyzed Grignard coupling: regio- and stereoselective monoalkylation and -arylation of 1,1-dichloro-1-alkenes

1987 • 150 citations

Creation of Liquid Crystal Waveguides with Scanning Force Microscopy

1994 • 109 citations

Biosynthesis of the erythromycin macrolactone and a rational approach for producing hybrid macrolides

1992 • 49 citations