Neuronal expression of inducible nitric oxide synthase after oxygen and glucose deprivation in rat forebrain slices

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Nitric oxide synthases in mammals

1994 • 2,762 citations

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

1993 • 2,423 citations

Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis

1995 • 2,386 citations

Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase.

1994 • 2,216 citations

The Role of Glutamate Neurotoxicity in Hypoxic-Ischemic Neuronal Death

1990 • 2,204 citations

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.

1991 • 2,173 citations

Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase

1994 • 1,578 citations

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells.

1992 • 1,524 citations

The glucose oxidase-DAB-nickel method in peroxidase histochemistry of the nervous system

1988 • 1,235 citations

Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide.

1993 • 1,127 citations

Nitric Oxide: Pathophysiological Mechanisms

1995 • 876 citations

Tumor necrosis factor-alpha expression in ischemic neurons.

1994 • 793 citations

Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes.

1993 • 671 citations

Widespread tissue distribution, species distribution and changes in activity of Ca²⁺‐dependent and Ca²⁺‐independent nitric oxide synthases

1991 • 645 citations

Nitric Oxide Measured by a Porphyrinic Micro Sensor in Rat Brain after Transient Middle Cerebral Artery Occlusion

1993 • 632 citations

A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter.

1995 • 630 citations

Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme.

1992 • 616 citations

Nitric oxide mediates neuronal death after focal cerebral ischemia in the mouse

1991 • 509 citations

Induction of Nitric Oxide Synthase in Glial Cells

1992 • 501 citations

Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures.

1992 • 484 citations

Progression from ischemic injury to infarct following middle cerebral artery occlusion in the rat.

1993 • 484 citations

Inducible Nitric Oxide Synthase Gene Expression in Brain following Cerebral Ischemia

1995 • 479 citations

Neuron Specific Enolase, A Clinically Useful Marker for Neurons and Neuroendocrine Cells

1987 • 414 citations

Localization of nitric oxide synthase in the adult rat brain

1994 • 382 citations

Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage

1995 • 378 citations

Induction of Interleukin‐1β mRNA in Rat Brain After Transient Forebrain Ischemia

1992 • 336 citations

Interleukin-1 beta mRNA expression in ischemic rat cortex.

1993 • 335 citations

Expression of the inducible form of nitric oxide synthase by reactive astrocytes after transient global ischemia

1994 • 327 citations

Nitric oxide and peroxynitrite exert distinct effects on mitochondrial respiration which are differentially blocked by glutathione or glucose

1996 • 320 citations

Protein determination using bicinchoninic acid in the presence of sulfhydryl reagents

1988 • 311 citations

Cytokine-treated human neutrophils contain inducible nitric oxide synthase that produces nitration of ingested bacteria.

1996 • 310 citations

Pyrrolidine Dithiocarbamate Inhibits Induction of Nitric Oxide Synthase Activity in Rat Alveolar Macrophages

1993 • 249 citations

The cellular function of MASH1 in autonomic neurogenesis

1995 • 241 citations

Demonstration of poly-N-acetyl lactosamine residues in ameboid and ramified microglial cells in rat brain by tomato lectin binding.

1994 • 199 citations

Cerebral endothelial nitric oxide synthase expression after focal cerebral ischemia in rats.

1993 • 182 citations

Involvement of cytokines in acute neurodegeneration in the CNS

1993 • 169 citations

Expression of inducible nitric oxide synthase by neurones following exposure to endotoxin and cytokine

1994 • 157 citations

Preparative methods for brain slices: a discussion

1995 • 155 citations

Nitric Oxide Production and Neurotoxicity Mediated by Activated Microglia from Human versus Mouse Brain

1994 • 128 citations

Cytokines Regulate L‐Arginine‐Dependent Cyclic GMP Production in Rat Glial Cells

1993 • 124 citations

The heterogeneous temporal evolution of focal ischemic neuronal damage in the rat

1993 • 109 citations

On the preparation of brain slices: morphology and cyclic nucleotides

1979 • 107 citations

NADPH-diaphorase activity in activated astrocytes represents inducible nitric oxide synthase

1994 • 104 citations

Cyclic GMP and cell death in rat cerebellar slices

1988 • 92 citations

In Vivo Expression of Inducible Nitric Oxide Synthase in Cerebellar Neurons

1996 • 85 citations

Microglial response to N-methyl-D-aspartate-mediated excitotoxicity in the immature rat brain

1996 • 65 citations

Inhibition by Lamotrigine of the Generation of Nitric Oxide in Rat Forebrain Slices

1995 • 48 citations

Age-related changes of oxygen free radical production in the rat brain slice after hypoxia: on-line measurement using enhanced chemiluminescence

1995 • 40 citations

Microglia in normal and regenerating visual pathways of the tench (Tinca tinca L., 1758; Teleost) : a study with tomato lectin

1995 • 34 citations