Signal Regulatory Proteins Negatively Regulate Immunoreceptor-dependent Cell Activation

SRα Promoter: an Efficient and Versatile Mammalian cDNA Expression System Composed of the Simian Virus 40 Early Promoter and the R-U5 Segment of Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat

1988 • 1,351 citations

Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors.

1979 • 1,301 citations

F<scp>c</scp>RECEPTOR BIOLOGY

1997 • 1,219 citations

Establishment of an immature mast cell line from a patient with mast cell leukemia

1988 • 749 citations

Monoclonal dinitrophenyl-specific murine IgE antibody: preparation, isolation, and characterization.

1980 • 653 citations

A family of proteins that inhibit signalling through tyrosine kinase receptors

1997 • 648 citations

Recruitment of Tyrosine Phosphatase HCP by the Killer Cell Inhibitory Receptor

1996 • 625 citations

IgE‐induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones

1981 • 586 citations

Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains

1995 • 575 citations

Complete structure and expression in transfected cells of high affinity IgE receptor

1989 • 515 citations

Antigen and Fc receptor signaling. The awesome power of the immunoreceptor tyrosine-based activation motif (ITAM).

1995 • 463 citations

The same tyrosine-based inhibition motif, in the intra-cytoplasmic domain of FcγRIIB, regulates negatively BCR-, TCR-, and FcR-dependent cell activation

1995 • 448 citations

A Novel Membrane Glycoprotein, SHPS-1, That Binds the SH2-Domain-Containing Protein Tyrosine Phosphatase SHP-2 in Response to Mitogens and Cell Adhesion

1996 • 443 citations

Major histocompatibility complex class I‐specific receptors on human natural killer and T lymphocytes

1997 • 360 citations

Integrin-associated Protein Is a Ligand for the P84 Neural Adhesion Molecule

1999 • 347 citations

Sequential Involvement of Lck and SHP-1 with MHC-Recognizing Receptors on NK Cells Inhibits FcR-Initiated Tyrosine Kinase Activation

1996 • 341 citations

Selective growth of human mast cells induced by Steel factor, IL-6, and prostaglandin E2 from cord blood mononuclear cells.

1996 • 324 citations

Phosphorylation and dephosphorylation of the high-affinity receptor for immunoglobulin E immediately after receptor engagement and disengagement

1991 • 272 citations

A macrophage Fcγ receptor and the mast cell receptor for IgE share an identical subunit

1989 • 268 citations

The Steel/W transduction pathway: kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the Steel factor.

1991 • 264 citations

A new leukemia cell line with philadelphia chromosome characterized as basophil precursors

1985 • 261 citations

Signal-Regulatory Protein Is Selectively Expressed by Myeloid and Neuronal Cells

1998 • 248 citations

Costimulation of T Cell Activation by Integrin-associated Protein (CD47) Is an Adhesion-dependent, CD28-independent Signaling Pathway

1997 • 236 citations

High Expression of Inhibitory Receptor SHPS-1 and Its Association with Protein-tyrosine Phosphatase SHP-1 in Macrophages

1998 • 233 citations

CD47 mediates post-adhesive events required for neutrophil migration across polarized intestinal epithelia.

1996 • 221 citations

Identification of Major Binding Proteins and Substrates for the SH2-Containing Protein Tyrosine Phosphatase SHP-1 in Macrophages

1998 • 201 citations

Fc epsilon receptor I-associated lyn-dependent phosphorylation of Fc gamma receptor IIB during negative regulation of mast cell activation.

1998 • 179 citations

The Emerging Field of Receptor-Mediated Inhibitory Signaling: SHP or SHIP?

1996 • 174 citations

Fcε Receptor I-Associatedlyn-Dependent Phosphorylation of Fcγ Receptor IIB During Negative Regulation of Mast Cell Activation

1998 • 150 citations

Association of IgA-Fc receptors (Fc alpha R) with Fc epsilon RI gamma 2 subunits in U937 cells. Aggregation induces the tyrosine phosphorylation of gamma 2.

1994 • 146 citations

Selective in vivo recruitment of the phosphatidylinositol phosphatase SHIP by phosphorylated FcγRIIB during negative regulation of IgE-dependent mouse mast cell activation

1996 • 125 citations

Differential Roles of N- and C-Terminal Immunoreceptor Tyrosine-Based Inhibition Motifs During Inhibition of Cell Activation by Killer Cell Inhibitory Receptors

1999 • 112 citations

Growth Hormone Regulation of SIRP and SHP-2 Tyrosyl Phosphorylation and Association

1998 • 100 citations

Physical association between the high-affinity IgG receptor (Fc gamma RI) and the gamma subunit of the high-affinity IgE receptor (Fc epsilon RI gamma).

1993 • 95 citations

Activation of Protein-tyrosine Phosphatase SH-PTP2 by a Tyrosine-based Activation Motif of a Novel Brain Molecule

1996 • 95 citations

Ligand-induced dimerization of growth factor receptors: Variations on the theme

1996 • 92 citations

CTLA‐4, a Negative Regulator of T‐Lymphocyte Activation

1996 • 91 citations

Phenotypic Characterization of Human Skin Mast Cells by Combined Staining with Toluidine Blue and CD Antibodies

1998 • 87 citations

Murine recombinant Fc gamma RIII, but not Fc gamma RII, trigger serotonin release in rat basophilic leukemia cells.

1992 • 80 citations

Involvement of SHP-2 in multiple aspects of IL-2 signaling: evidence for a positive regulatory role.

1998 • 74 citations

Induction of tumor necrosis factor-alpha production by mast cells via Fc gamma R. Role of the Fc gamma RIII gamma subunit.

1992 • 71 citations

Cutting Edge: Involvement of SHP-2 in Multiple Aspects of IL-2 Signaling: Evidence for a Positive Regulatory Role

1998 • 63 citations

Negative regulation of c-kit-mediated cell proliferation by Fc gamma RIIB.

1999 • 63 citations

Negative Regulation of c-kit-Mediated Cell Proliferation by FcγRIIB

1999 • 50 citations

Rh-Deficiency of the Regulator Type Caused by Splicing Mutations in the Human RH50 Gene

1998 • 35 citations

Src Kinase Tyrosine Phosphorylates PTP1C, a Protein Tyrosine Phosphatase Containing Src Homology-2 Domains That Down-Regulates Cell Proliferation

1994 • 32 citations

Integrin-Associated Protein (IAP, Also Termed CD47) Is Involved in Stroma-Supported Erythropoiesis

1998 • 27 citations