Activation of Protein-tyrosine Phosphatase SH-PTP2 by a Tyrosine-based Activation Motif of a Novel Brain Molecule

Solid phase peptide synthesis utilizing 9‐fluorenylmethoxycarbonyl amino acids

1990 • 2,426 citations

ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain

1992 • 1,037 citations

SH2 and SH3 domains

1993 • 697 citations

SH2-Containing Phosphotyrosine Phosphatase as a Target of Protein-Tyrosine Kinases

1993 • 666 citations

Activation of a Phosphotyrosine Phosphatase by Tyrosine Phosphorylation

1993 • 554 citations

T cell antigen receptor signal transduction: A tale of tails and cytoplasmic protein-tyrosine kinases

1993 • 552 citations

A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase

1994 • 477 citations

corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso

1992 • 400 citations

Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras.

1994 • 389 citations

The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp

1993 • 384 citations

Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation.

1994 • 369 citations

Identification of a human src homology 2-containing protein-tyrosine-phosphatase: a putative homolog of Drosophila corkscrew.

1992 • 359 citations

Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor

1995 • 349 citations

Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production.

1991 • 349 citations

The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early xenopus development

1995 • 330 citations

Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor.

1993 • 319 citations

Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin.

1994 • 302 citations

Tyrosine kinases and tyrosine-based activation motifs. Current research on activation via the T cell antigen receptor.

1992 • 287 citations

Potent Stimulation of SH-PTP2 Phosphatase Activity by Simultaneous Occupancy of Both SH2 Domains

1995 • 276 citations

Protein-tyrosine-phosphatase SHPTP2 is a required positive effector for insulin downstream signaling.

1995 • 263 citations

Protein-tyrosine kinase p72syk in high affinity IgE receptor signaling. Identification as a component of pp72 and association with the receptor gamma chain after receptor aggregation.

1993 • 232 citations

Regulation of Phosphatidylinositol 3′-Kinase by Tyrosyl Phosphoproteins

1995 • 222 citations

A widely expressed human protein-tyrosine phosphatase containing src homology 2 domains.

1993 • 219 citations

The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp.

1993 • 214 citations

Activation of the SH2-containing protein tyrosine phosphatase, SH-PTP2, by phosphotyrosine-containing peptides derived from insulin receptor substrate-1.

1994 • 212 citations

Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2

1996 • 193 citations

Tyrosyl phosphorylation and growth factor receptor association of the human corkscrew homologue, SH-PTP2

1993 • 192 citations

The ubiquitously expressed Syp phosphatase interacts with c-kit and Grb2 in hematopoietic cells.

1994 • 151 citations

Synthesis of phosphotyrosine-containing peptides and their use as substrates for protein tyrosine phosphatases

1993 • 101 citations

Characterization of protein tyrosine phosphatase SH-PTP2. Study of phosphopeptide substrates and possible regulatory role of SH2 domains.

1994 • 92 citations

Molecular cloning of a novel protein‐tyrosine phosphatase SH‐PTP3 with sequence similarity to the src‐homology region 2

1992 • 89 citations

Purification and characterization of PTP2C, a widely distributed protein tyrosine phosphatase containing two SH2 domains.

1994 • 85 citations

Altered Expression of Protein-tyrosine Phosphatase 2C in 293 Cells Affects Protein Tyrosine Phosphorylation and Mitogen-activated Protein Kinase Activation

1995 • 83 citations

Membrane immunoglobulin and its accomplices: new lessons from an old receptor ¹

1992 • 83 citations

Regulation of the Src tyrosine kinase and Syp tyrosine phosphatase by their cellular association.

1995 • 80 citations

Protein tyrosine kinases and phosphatases in the nervous system

1991 • 59 citations

Role of the CD45 tyrosine phosphatase in signal transduction in the immune system

1993 • 57 citations

Localization and Subcellular Distribution of SH-PTP2, a Protein-Tyrosine-Phosphatase with Src Homology-2 Domains, in Rat Brain

1995 • 30 citations

Cloning, Expression and Mutational Analysis of SH-PTP2, Human Protein-Tyrosine Phosphatase

1993 • 24 citations

A Novel Brain-Specific Antigen: A Glycoprotein Electrophoretically Similar to but Immunochemically Different from Type B Nucleoside Diphosphatase1

1989 • 22 citations

[34] Renaturation of protein kinase activity on protein blots

1991 • 21 citations

Src Family Kinases Control Neural Development and Function

1994 • 19 citations

Purification and characterization of a rat liver protein‐tyrosine phosphatase with sequence similarity to src‐homology region 2

1992 • 17 citations

Oligosaccharide‐Related Epitope Specific for a Brain‐Specific Glycoprotein, 1D4 Antigen

1990 • 10 citations