Import pathways of precursor proteins into mitochondria: multiple receptor sites are followed by a common membrane insertion site.

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 • 4,231 citations

An Efficient mRNA‐Dependent Translation System from Reticulocyte Lysates

1976 • 3,994 citations

Fluorographic detection of radioactivity in polyacrylamide gols with the water-soluble fluor, sodium salicylate

1979 • 1,976 citations

Mitochondrial targeting sequences may form amphiphilic helices.

1986 • 1,019 citations

Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria

1986 • 723 citations

A chemically synthesized pre-sequence of an imported mitochondrial protein can form an amphiphilic helix and perturb natural and artificial phospholipid bilayers.

1986 • 493 citations

Transport of proteins into mitochondria: Translocational intermediates spanning contact sites between outer and inner membranes

1985 • 470 citations

Mitochondrial protein import: Identification of processing peptidase and of PEP, a processing enhancing protein

1988 • 388 citations

Import of proteins into mitochondria. Energy-dependent uptake of precursors by isolated mitochondria.

1982 • 351 citations

Transport into mitochondria and intramitochondrial sorting of the Fe/S protein of ubiquinol-cytochrome c reductase

1986 • 340 citations

Mitochondrial protein import: Nucleoside triphosphates are involved in conferring import-competence to precursors

1987 • 322 citations

How proteins find mitochondria and intramitochondrial compartments

1986 • 302 citations

Successive translocation into and out of the mitochondrial matrix: Targeting of proteins to the intermembrane space by a bipartite signal peptide

1987 • 275 citations

Distinct steps in the import of ADP/ATP carrier into mitochondria.

1987 • 248 citations

Transport of proteins into mitochondria: a potassium diffusion potential is able to drive the import of ADP/ATP carrier.

1985 • 245 citations

A leader peptide is sufficient to direct mitochondrial import of a chimeric protein.

1985 • 239 citations

Characterization of translocation contact sites involved in the import of mitochondrial proteins.

1987 • 219 citations

Import of proteins into mitochondria. Partial purification of a matrix-located protease involved in cleavage of mitochondrial precursor polypeptides.

1983 • 201 citations

Protein unfolding and the energetics of protein translocation across biological membranes

1988 • 192 citations

Transport of F₁‐ATPase subunit β into mitochondria depends on both a membrane potential and nucleoside triphosphates

1986 • 182 citations

Phosphodiester bond cleavage outside mitochondria is required for the completion of protein import into the mitochondrial matrix

1987 • 175 citations

A neutral metallo endoprotease involved in the processing of an F1-ATPase subunit precursor in mitochondria.

1982 • 167 citations

Mitochondrial porin of Neurospora crassa: cDNA cloning, in vitro expression and import into mitochondria.

1987 • 163 citations

The carboxyl-terminal two-thirds of the ADP/ATP carrier polypeptide contains sufficient information to direct translocation into mitochondria.

1987 • 160 citations

Assembly of Cytochrome c. Apocytochrome c Is Bound to Specific Sites on Mitochondria before Its Conversion to Holocytochrome c

1981 • 157 citations

Processing peptidase of Neurospora mitochondria. Two-step cleavage of imported ATPase subunit 9

1984 • 157 citations

Yeast mitochondrial outer membrane specifically binds cytoplasmically-synthesized precursors of mitochondrial proteins

1983 • 149 citations

Proteinaceous receptors for the import of mitochondrial precursor proteins.

1984 • 148 citations

Membrane and cytosolic components affecting transport of the precursor for ornithine carbamyltransferase into mitochondria.

1983 • 141 citations

Mitochondrial protein import: involvement of the mature part of a cleavable precursor protein in the binding to receptor sites.

1987 • 134 citations

Different Transport Pathways of Individual Precursor Proteins in Mitochondria

1981 • 133 citations

Mitochondrial protein import

1989 • 131 citations

Import of cytochrome c into mitochondria. Cytochrome c heme lyase

1987 • 130 citations

The primary structure of the iron-sulfur subunit of ubiquinol-cytochrome c reductase from Neurospora, determined by cDNA and gene sequencing

1985 • 125 citations

Processing of pre-ornithine transcarbamylase requires a zinc-dependent protease localized to the mitochondrial matrix

1982 • 124 citations

Receptor sites involved in posttranslational transport of apocytochrome c into mitochondria: specificity, affinity, and number of sites.

1983 • 122 citations

Import of an incompletely folded precursor protein into isolated mitochondria requires an energized inner membrane, but no added ATP.

1987 • 119 citations

A Mitochondria1 Protease that Cleaves the Precursor of Ornithine Carbamoyltransferase

1982 • 110 citations

Transfer of proteins into mitochondria. Precursor to the ADP/ATP carrier binds to receptor sites on isolated mitochondria.

1983 • 98 citations

A water-soluble form of porin from the mitochondrial outer membrane of Neurospora crassa. Properties and relationship to the biosynthetic precursor form.

1985 • 97 citations

Disruption of the outer membrane restores protein import to trypsin-treated yeast mitochondria.

1987 • 96 citations

Precursor proteins are transported into mitochondria in the absence of proteolytic cleavage of the additional sequences.

1983 • 95 citations

High-affinity binding sites involved in the import of porin into mitochondria.

1987 • 92 citations

Mitochondrial precursor proteins are imported through a hydrophilic membrane environment

1987 • 90 citations

Deficiency in mRNA splicing in a cytochrome c mutant of neurospora crassa: importance of carboxy terminus for import of apocytochrome c into mitochondria.

1987 • 80 citations

Role of ATP in mitochondrial protein import. Conformational alteration of a precursor protein can substitute for ATP requirement.

1988 • 76 citations

Protein import into yeast mitochondria is inhibited by antibodies raised against 45-kd proteins of the outer membrane.

1987 • 72 citations

Biogenesis of Mitochondrial Energy Transducing Complexes

1987 • 60 citations

Mitochondrial protein import: Differential recognition of various transport intermediates by antibodies

1988 • 23 citations

Biosynthesis and assembly of mitochondrial proteins

1988 • 20 citations

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