A Genetic Variant BDNF Polymorphism Alters Extinction Learning in Both Mouse and Human

Emotion Circuits in the Brain

2000 • 8,055 citations

Translational Findings on Brain-Derived Neurotrophic Factor and Anxiety: Contributions from Basic Research to Clinical Practice

2013 • 3,921 citations

The BDNF val66met Polymorphism Affects Activity-Dependent Secretion of BDNF and Human Memory and Hippocampal Function

2003 • 3,746 citations

Neurobiology of Depression

2002 • 3,057 citations

Neurons in medial prefrontal cortex signal memory for fear extinction

2002 • 1,785 citations

Extinction Learning in Humans

2004 • 1,711 citations

Psychobiological Mechanisms of Resilience and Vulnerability: Implications for Successful Adaptation to Extreme Stress

2004 • 1,562 citations

Human Amygdala Activation during Conditioned Fear Acquisition and Extinction: a Mixed-Trial fMRI Study

1998 • 1,389 citations

Neurocircuitry Models of Posttraumatic Stress Disorder and Extinction: Human Neuroimaging Research—Past, Present, and Future

2006 • 1,309 citations

Genetic Variant BDNF (Val66Met) Polymorphism Alters Anxiety-Related Behavior

2006 • 1,289 citations

Recall of Fear Extinction in Humans Activates the Ventromedial Prefrontal Cortex and Hippocampus in Concert

2007 • 1,129 citations

Exaggerated amygdala response to masked facial stimuli in posttraumatic stress disorder: a functional MRI study

2000 • 1,097 citations

Brain-Derived Neurotrophic Factor val⁶⁶met Polymorphism Affects Human Memory-Related Hippocampal Activity and Predicts Memory Performance

2003 • 1,022 citations

Classical fear conditioning in the anxiety disorders: a meta-analysis

2005 • 1,000 citations

Stimulation of Medial Prefrontal Cortex Decreases the Responsiveness of Central Amygdala Output Neurons

2003 • 926 citations

Behavioral and Neural Analysis of Extinction

2002 • 906 citations

Neural Circuitry Underlying the Regulation of Conditioned Fear and Its Relation to Extinction

2008 • 698 citations

Brain activation in PTSD in response to trauma-related stimuli

1999 • 613 citations

Context-Dependent Human Extinction Memory Is Mediated by a Ventromedial Prefrontal and Hippocampal Network

2006 • 482 citations

Applying Learning Principles to the Treatment of Post‐Trauma Reactions

2003 • 445 citations

Brain Mechanisms of Fear Extinction: Historical Perspectives on the Contribution of Prefrontal Cortex

2006 • 427 citations

Brain-Derived Neurotrophic Factor Val66Met and Psychiatric Disorders: Meta-Analysis of Case-Control Studies Confirm Association to Substance-Related Disorders, Eating Disorders, and Schizophrenia

2007 • 424 citations

From Fear to Safety and Back: Reversal of Fear in the Human Brain

2008 • 419 citations

Life Stress, Genes, and Depression: Multiple Pathways Lead to Increased Risk and New Opportunities for Intervention

2004 • 414 citations

Extending animal models of fear conditioning to humans

2006 • 354 citations

Human orbitofrontal cortex mediates extinction learning while accessing conditioned representations of value

2004 • 347 citations

BDNF Variation and Mood Disorders: A Novel Functional Promoter Polymorphism and Val66Met are Associated with Anxiety but Have Opposing Effects

2005 • 245 citations

Amygdala BDNF signaling is required for consolidation but not encoding of extinction

2006 • 235 citations

Delayed Recall of Fear Extinction in Rats With Lesions of Ventral Medial Prefrontal Cortex

2004 • 205 citations

Brain-Derived Neurotrophic Factor in Amygdala-Dependent Learning

2005 • 140 citations

Variant BDNF Val66Met Polymorphism Affects Extinction of Conditioned Aversive Memory

2009 • 137 citations

Electrolytic lesions of the amygdala block acquisition and expression of fear-potentiated startle even with extensive training but do not prevent reacquisition.

1993 • 130 citations

Electrolytic lesions of the amygdala block acquisition and expression of fear-potentiated startle even with extensive training but do not prevent reacquisition.

1993 • 101 citations

The dopaminergic modulation of fear: Quinpirole impairs the recall of emotional memories in rats.

1999 • 95 citations

The dopaminergic modulation of fear: Quinpirole impairs the recall of emotional memories in rats.

1999 • 89 citations

Association between BDNF Val66Met polymorphism and trait depression is mediated via resting EEG alpha band activity

2008 • 72 citations