Brain-Derived Neurotrophic Factor in Amygdala-Dependent Learning

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Emotion Circuits in the Brain

2000 • 8,055 citations

In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector

1996 • 4,854 citations

Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants

2003 • 4,175 citations

The Emotional Brain: The Mysterious Underpinnings of Emotional Life

2004 • 4,130 citations

The BDNF val66met Polymorphism Affects Activity-Dependent Secretion of BDNF and Human Memory and Hippocampal Function

2003 • 3,746 citations

Synaptic Activity and the Construction of Cortical Circuits

1996 • 3,004 citations

The Role of the Amygdala in Fear and Anxiety

1992 • 2,216 citations

Neurotrophins and Neuronal Plasticity

1995 • 1,937 citations

Neurotrophins as synaptic modulators

2001 • 1,773 citations

Hippocampal Volume Reduction in Major Depression

2000 • 1,645 citations

Chronic Stress Induces Contrasting Patterns of Dendritic Remodeling in Hippocampal and Amygdaloid Neurons

2002 • 1,607 citations

Molecular cloning and expression of brain-derived neurotrophic factor

1989 • 1,453 citations

Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor.

1995 • 1,416 citations

Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus

1995 • 1,354 citations

NEUROTROPHINS AND SYNAPTIC PLASTICITY

1999 • 1,343 citations

Fear conditioning induces associative long-term potentiation in the amygdala

1997 • 1,285 citations

Cortical pathways to the mammalian amygdala

1998 • 1,245 citations

Recombinant BDNF Rescues Deficits in Basal Synaptic Transmission and Hippocampal LTP in BDNF Knockout Mice

1996 • 1,219 citations

Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus

1996 • 1,104 citations

Distribution of Brain-Derived Neurotrophic Factor (BDNF) Protein and mRNA in the Normal Adult Rat CNS: Evidence for Anterograde Axonal Transport

1997 • 1,093 citations

Brain-Derived Neurotrophic Factor val⁶⁶met Polymorphism Affects Human Memory-Related Hippocampal Activity and Predicts Memory Performance

2003 • 1,022 citations

Neurotrophins regulate dendritic growth in developing visual cortex

1995 • 963 citations

Why We Think Plasticity Underlying Pavlovian Fear Conditioning Occurs in the Basolateral Amygdala

1999 • 885 citations

Multiple promoters direct tissue-specific expression of the rat BDNF gene

1993 • 851 citations

Emotional memory systems in the brain

1993 • 805 citations

trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors.

1991 • 785 citations

Fear conditioning induces a lasting potentiation of synaptic currents in vitro

1997 • 772 citations

Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF

1993 • 753 citations

The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain

1990 • 748 citations

Conditional Deletion Of Brain-Derived Neurotrophic Factor in the Postnatal Brain Leads to Obesity and Hyperactivity

2001 • 738 citations

Functional anatomical abnormalities in limbic and prefrontal cortical structures in major depression

2000 • 651 citations

Neural plasticity to stress and antidepressant treatment

1999 • 638 citations

Rapid and selective induction of BDNF expression in the hippocampus during contextual learning

2000 • 616 citations

Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors.

1995 • 612 citations

Neurotrophin expression in rat hippocampal slices: A stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs

1992 • 564 citations

Neurobiology of fear responses: the role of the amygdala

1997 • 556 citations

Involvement of Brain-Derived Neurotrophic Factor in Spatial Memory Formation and Maintenance in a Radial Arm Maze Test in Rats

2000 • 539 citations

Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma.

1992 • 521 citations

Expression of brain-derived neurotrophic factor protein in the adult rat central nervous system

1997 • 500 citations

Neurotrophins and Time: Different Roles for TrkB Signaling in Hippocampal Long-Term Potentiation

1997 • 482 citations

Naturally Occurring Truncated trkB Receptors Have Dominant Inhibitory Effects on Brain-Derived Neurotrophic Factor Signaling

1996 • 472 citations

Learning Deficit in BDNF Mutant Mice

1997 • 470 citations

Impairments in High-Frequency Transmission, Synaptic Vesicle Docking, and Synaptic Protein Distribution in the Hippocampus of BDNF Knockout Mice

1999 • 463 citations

The TrkB-Shc Site Signals Neuronal Survival and Local Axon Growth via MEK and PI3-Kinase

2000 • 431 citations

Brain-derived neurotrophic factor modulates hippocampal synaptic transmission by increasing N -methyl- <scp>d</scp> -aspartic acid receptor activity

1998 • 406 citations

Memory Consolidation for Contextual and Auditory Fear Conditioning Is Dependent on Protein Synthesis, PKA, and MAP Kinase

1999 • 403 citations

Amygdala and Hippocampal Volumes in Adolescents and Adults With Bipolar Disorder

2003 • 390 citations

Exercise-induced regulation of brain-derived neurotrophic factor (BDNF) transcripts in the rat hippocampus

1998 • 360 citations

Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: implications for the pathophysiology and treatment of manic–depressive illness

2000 • 352 citations

Synaptic plasticity and mood disorders

2002 • 351 citations

Brain-Derived Neurotrophic Factor and Tyrosine Kinase Receptor B Involvement in Amygdala-Dependent Fear Conditioning

2004 • 351 citations

Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice.

1996 • 350 citations

A Role for the PI-3 Kinase Signaling Pathway in Fear Conditioning and Synaptic Plasticity in the Amygdala

2001 • 339 citations

Activity-Dependent Dendritic Targeting of BDNF and TrkB mRNAs in Hippocampal Neurons

1997 • 333 citations

The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus

1993 • 313 citations

Brain-Derived Neurotrophic Factor Triggers Transcription-Dependent, Late Phase Long-Term PotentiationIn Vivo

2002 • 301 citations

Deprivation of endogenous brain-derived neurotrophic factor results in impairment of spatial learning and memory in adult rats

1999 • 281 citations

Differential regulation of Brain Derived Neurotrophic Factor transcripts by antidepressant treatments in the adult rat brain

2003 • 274 citations

The role of the amygdala in conditioned and unconditioned fear and anxiety

2000 • 251 citations

MRI investigation of temporal lobe structures in bipolar patients

2003 • 231 citations

Brain-derived neurotrophic factor antisense oligonucleotide impairs memory retention and inhibits long-term potentiation in rats

1997 • 226 citations

Regulation of Synaptic Plasticity Genes during Consolidation of Fear Conditioning

2002 • 217 citations

Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: A mechanism to facilitate encoding and circuit maintenance?

1998 • 205 citations

Initial conditions of serotonin transporter kinetics and genotype: influence on ssri treatment trial outcome

2002 • 195 citations

Volumetric MRI studies of mood disorders: do they distinguish unipolar and bipolar disorder?

2002 • 193 citations

Trophic regulation of synaptic plasticity

1999 • 187 citations

Internal initiation of translation of five dendritically localized neuronal mRNAs

2001 • 160 citations

Dual Stem Loops within the Poliovirus Internal Ribosomal Entry Site Control Neurovirulence

1999 • 155 citations

Brain Imaging Studies in Mood and Anxiety Disorders

2003 • 153 citations

Unilateral LTP triggers bilateral increases in hippocampal neurotrophin andtrk receptor mRNA expression in behaving rats: Evidence for interhemispheric communication

1996 • 137 citations

Differential regulation of brain-derived neurotrophic factor transcripts during the consolidation of fear learning

2004 • 131 citations

Biological characterization and optical imaging of brain‐derived neurotrophic factor‐green fluorescent protein suggest an activity‐dependent local release of brain‐derived neurotrophic factor in neurites of cultured hippocampal neurons

2001 • 127 citations

Truncated trkB.T1 Is Dominant Negative Inhibitor of trkB.TK+-Mediated Cell Survival

2001 • 127 citations

Brain-Derived Neurotrophic Factor (BDNF) Induces Dendritic Targeting of BDNF and Tyrosine Kinase B mRNAs in Hippocampal Neurons through a Phosphatidylinositol-3 Kinase-Dependent Pathway

2000 • 121 citations

Involvement of the amygdaloid complex in neuromodulatory influences on memory storage

1990 • 119 citations

Correlation between hippocampal BDNF mRNA expression and memory performance in senescent rats

2001 • 117 citations

Brain Insults in Rats Induce Increased Expression of the BDNF Gene through Differential Use of Multiple Promoters

1994 • 113 citations

Signaling mechanisms mediating BDNF modulation of memory formation in vivo in the hippocampus.

2002 • 112 citations

Local Effects of BDNF on Dendritic Growth

2004 • 99 citations

Chapter 15 Brain derived neurotrophic factor

1987 • 94 citations

Involvement of NMDA receptors within the amygdala in short- versus long-term memory for fear conditioning as assessed with fear-potentiated startle.

2000 • 90 citations

Methods in Nutrition Science: Cre/loxP System for Generating Tissue-specific Knockout Mouse Models

2004 • 71 citations

Alternate 5′ exons in the rat brain-derived neurotrophic factor gene: differential patterns of expression across brain regions

1994 • 67 citations

N-myc translation is initiated via an internal ribosome entry segment that displays enhanced activity in neuronal cells

2001 • 62 citations

Role of brain-derived neurotrophic factor and presynaptic proteins in passive avoidance learning in day-old domestic chicks

1999 • 42 citations

Disparate effects of long-term potentiation on evoked potentials and single CA1 neurons in the hippocampus of anesthetized rats

2000 • 24 citations

Genetics of Childhood Disorders: L. Learning and Memory, Part 3: Fear Conditioning

2003 • 12 citations