Constitutive and Variable Regions of Z-disk Titin/Connectin in Myofibril Formation: A Dominant-negative Screen.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

Antibodies, a laboratory manual

1989 • 12,929 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Genomic sequencing.

1984 • 8,343 citations

Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme

1989 • 1,244 citations

Titins: Giant Proteins in Charge of Muscle Ultrastructure and Elasticity

1995 • 1,195 citations

Use of an oriented peptide library to determine the optimal substrates of protein kinases

1994 • 645 citations

The organization of titin filaments in the half-sarcomere revealed by monoclonal antibodies in immunoelectron microscopy: a map of ten nonrepetitive epitopes starting at the Z line extends close to the M line.

1988 • 608 citations

Titin: major myofibrillar components of striated muscle.

1979 • 523 citations

The Structural Basis of Muscular Contraction

1981 • 391 citations

Towards a molecular understanding of titin.

1992 • 338 citations

Myogenesis in the mouse embryo: differential onset of expression of myogenic proteins and the involvement of titin in myofibril assembly.

1989 • 297 citations

A Molecular Map of the Interactions between Titin and Myosin‐Binding Protein C

1996 • 272 citations

Myogenic Cell Lines Derived from Transgenic Mice Carrying a Thermolabile T Antigen: A Model System for the Derivation of Tissue-Specific and Mutation-Specific Cell Lines

1994 • 263 citations

Architecture of the sarcomere matrix of skeletal muscle: immunoelectron microscopic evidence that suggests a set of parallel inextensible nebulin filaments anchored at the Z line.

1988 • 261 citations

Viscoelasticity of the sarcomere matrix of skeletal muscles. The titin-myosin composite filament is a dual-stage molecular spring

1993 • 251 citations

Does titin regulate the length of muscle thick filaments?

1989 • 240 citations

Connectin, an Elastic Protein of Muscle<subtitle>Characterization and Function<xref ref-type="fn" rid="fn1"><sup>1</sup></xref></subtitle>

1977 • 231 citations

The central Z-disk region of titin is assembled from a novel repeat in variable copy numbers

1996 • 168 citations

New elastic protein from muscle

1976 • 165 citations

Connectin, an Elastic Protein from Myofibrils1

1976 • 159 citations

Studies on cardiac myofibrillogenesis with antibodies to titin, actin, tropomyosin, and myosin.

1988 • 156 citations

Extensible and Less-Extensible Domains of Connectin Filaments in Stretched Vertebrate Skeletal Muscle Sarcomeres as Detected by Immunofluorescence and Immunoelectron Microscopy Using Monoclonal Antibodies1

1988 • 151 citations

Sequential appearance of muscle‐specific proteins in myoblasts as a function of time after cell division: Evidence for a conserved myoblast differentiation program in skeletal muscle

1994 • 139 citations

The muscle Z band: lessons in stress management

1994 • 125 citations

Phosphorylation of KSP motifs in the C-terminal region of titin in differentiating myoblasts.

1993 • 111 citations

Immunocytochemical studies of cardiac myofibrillogenesis in early chick embryos. II. Generation of alpha-actinin dots within titin spots at the time of the first myofibril formation.

1987 • 109 citations

Fine structure of wide and narrow vertebrate muscle Z-lines

1985 • 109 citations

Dominant negative effect of cytoplasmic actin isoproteins on cardiomyocyte cytoarchitecture and function.

1995 • 92 citations

Characterization of a 5.4 kb cDNA fragment from the Z-line region of rabbit cardiac titin reveals phosphorylation sites for proline-directed kinases

1995 • 63 citations

Purification and Biochemical Characterization of Myomesin, a Myosin‐Binding and Titin‐Binding Protein, from Bovine Skeletal Muscle

1995 • 48 citations

Skeletal muscle myofibrillogenesis as revealed with a monoclonal antibody to titin in combination with detection of the α- and γ-isoforms of actin

1989 • 46 citations

Titin Domain Patterns Correlate with the Axial Disposition of Myosin at the End of the Thick Filament

1996 • 46 citations

A 11.5-kb 5′-Terminal cDNA Sequence of Chicken Breast Muscle Connectin/Titin Reveals Its Z Line Binding Region

1996 • 39 citations

Purification and Characterization of the 1, 200-kDa Subfragment of Connectin Filaments Produced by 0.1 mM Calcium Ions1

1994 • 28 citations

Effects of different enzymic treatments on the release of titin fragments from rabbit skeletal myofibrils. Purification of an 800 kDa titin polypeptide

1993 • 26 citations

<b>INTERACTION BETWEEN TITIN AND α-ACTININ </b>

1992 • 18 citations

<b>Connectin causes aggregation of myosin rods but not of myosin </b><b>heads </b>

1985 • 10 citations