Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1.

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA

1985 • 2,505 citations

The biology of platelet-derived growth factor

1986 • 2,036 citations

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

1990 • 1,882 citations

Purification and Biochemical Characterization of the Promoter-Specific Transcription Factor, Sp1

1986 • 1,473 citations

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

1990 • 1,300 citations

Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome

1991 • 944 citations

New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.

1981 • 925 citations

Transforming growth factors produced by certain human tumor cells: polypeptides that interact with epidermal growth factor receptors.

1980 • 892 citations

cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines

1986 • 786 citations

Signal Transduction by the Platelet-Derived Growth Factor Receptor

1989 • 653 citations

Nephrogenic Rests, Nephroblastomatosis, and the Pathogenesis of Wilms' Tumor

1990 • 643 citations

Mutation and Cancer: A Model for Wilms' Tumor of the Kidney<xref ref-type="fn" rid="FN2">2</xref>

1972 • 623 citations

Binding of the Wilms' Tumor Locus Zinc Finger Protein to the EGR-1 Consensus Sequence

1990 • 588 citations

An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor

1990 • 577 citations

Repression of the Insulin-Like Growth Factor II Gene by the Wilms Tumor Suppressor WT1

1992 • 535 citations

Transcriptional Repression Mediated by the WT1 Wilms Tumor Gene Product

1991 • 492 citations

A human osteosarcoma cell line secretes a growth factor structurally related to a homodimer of PDGF A-chains

1986 • 418 citations

Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals.

1990 • 343 citations

Complete physical map of the WAGR region of 11p13 localizes a candidate Wilms' tumor gene

1990 • 264 citations

Possible positive autocrine feedback in the prereplicative phase of human fibroblasts

1987 • 234 citations

Regulation of cytomegalovirus gene expression: alpha and beta promoters are trans activated by viral functions in permissive human fibroblasts

1985 • 229 citations

Modulation of DNA Binding Specificity by Alternative Splicing of the Wilms Tumor wt1 Gene Transcript

1992 • 221 citations

EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors.

1991 • 218 citations

Early transcriptional events in cell growth

1990 • 192 citations

Platelet-derived growth factor A chain: gene structure, chromosomal location, and basis for alternative mRNA splicing.

1988 • 187 citations

Differential expression of platelet-derived growth factor receptors in human malignant glioma cell lines.

1991 • 181 citations

Zinc finger point mutations within the WT1 gene in Wilms tumor patients.

1992 • 159 citations

Structural characterization of the human platelet-derived growth factor A-chain cDNA and gene: alternative exon usage predicts two different precursor proteins.

1988 • 139 citations

Comparison of intra- and extracellular transforming growth factors from nontransformed and chemically transformed mouse embryo cells.

1983 • 132 citations

Alternative RNA splicing affects function of encoded platelet-derived growth factor A chain

1987 • 130 citations

Identification and Characterization of the Egr-1 Gene Product, a DNA-Binding Zinc Finger Protein Induced by Differentiation and Growth Signals

1990 • 108 citations

A human fibrosarcoma cell line producing multiplication stimulating activity (MSA)-related peptides

1978 • 97 citations

Sequences of the 5′ portion of the humanc-sisgene: characterization of the transcriptional promoter and regulation of expression of the protein product by 5' untranslated mRNA sequences

1987 • 87 citations

Epithelial tissue-derived growth factor-like polypeptides.

1983 • 85 citations

Simplified preparation of unidirectional deletion clones

1986 • 59 citations

Production of platelet‐derived growth factor by cultured Wilms' tumor cells and fetal kidney cells

1987 • 51 citations

Demonstration of an activated platelet-derived growth factor autocrine pathway and its role in human tumor cell proliferation in vitro.

1992 • 43 citations

Is PDGF really important? Testing the hypotheses

1991 • 41 citations

Structural Characterization of the Human Platelet-Derived Growth Factor A-Chain cDNA and Gene: Alternative Exon Usage Predicts Two Different Precursor Proteins

1988 • 27 citations

Platelet-derived growth factor A chain: Confirmation of localization of PDGFA to chromosome 7p22 and description of an unusual minisatellite

1992 • 10 citations