PHARMACOLOGICAL ASPECTS OF HUMAN AND CANINE NARCOLEPSY

The International Classification of Sleep Disorders

1991 • 4,790 citations

A PROPOSED MECHANISM OF EMOTION

1937 • 3,511 citations

Regularly Occurring Periods of Eye Motility, and Concomitant Phenomena, During Sleep

1953 • 2,341 citations

Central cholinergic pathways in the rat: An overview based on an alternative nomenclature (Ch1–Ch6)

1983 • 2,305 citations

Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle

1981 • 1,903 citations

Guidelines for the Multiple Sleep Latency Test (MSLT): A Standard Measure of Sleepiness

1986 • 1,608 citations

Brainstem Control of Wakefulness and Sleep

1990 • 1,188 citations

SALMONELLAS IN MEAT.

1964 • 1,158 citations

THE ASCENDING CHOLINERGIC RETICULAR SYSTEM: NEOCORTICAL, OLFACTORY AND SUBCORTICAL PROJECTIONS

1967 • 1,116 citations

Preferential activation of midbrain dopamine neurons by appetitive rather than aversive stimuli

1996 • 826 citations

Raphe unit activity in freely moving cats: Correlation with level of behavioral arousal

1979 • 809 citations

Neuronal activities in brain-stem cholinergic nuclei related to tonic activation processes in thalamocortical systems

1990 • 779 citations

Antidepressant and Circadian Phase-Shifting Effects of Light

1987 • 712 citations

Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus.

1990 • 643 citations

Neuronal excitability modulation over the sleep cycle: a structural and mathematical model

1975 • 636 citations

The dopamine transporter: immunochemical characterization and localization in brain

1995 • 586 citations

EFFECTS OF THYROTROPIN-RELEASING HORMONE IN DEPRESSION*1

1972 • 558 citations

Blockade by antidepressants and related compounds of biogenic amine uptake into rat brain synaptosomes: Most antidepressants selectively block norepinephrine uptake

1984 • 528 citations

Maintenance of wakefulness test: A polysomnographic technique for evaluating treatment efficacy in patients with excessive somnolence

1982 • 517 citations

Central cardiovascular effects of alpha adrenergic drugs: differences between catecholamines and imidazolines.

1984 • 508 citations

Magnocellular nuclei of the basal forebrain project to neocortex, brain stem, and olfactory bulb. Review of some functional correlates

1975 • 482 citations

Yohimbine: a pharmacological probe for study of the alpha 2-adrenoreceptor.

1983 • 435 citations

Acetylcholine Liberation from Cerebral Cortex during Paradoxical (REM) Sleep

1971 • 427 citations

Evidence for dopamine receptors mediating sedation in the mouse brain

1976 • 421 citations

The pedunculopontine nucleus

1991 • 417 citations

Paradoxical sleep and its chemical/structural substrates in the brain

1991 • 402 citations

A cholinergic mechanism in the brainstem reticular formation: Induction of paradoxical sleep

1964 • 394 citations

Mapping of cholinoceptive brainstem structures responsible for the generation of paradoxical sleep in the cat.

1989 • 380 citations

The Influence of Thalidomide on the Clinical and Immunologic Manifestation of Erythema Nodosum Leprosum

1993 • 379 citations

Pregnancy Outcome Following First-Trimester Exposure to Fluoxetine (Prozac)

1993 • 378 citations

Hippocampus norepinephrine, caudate dopamine and serotonin, and behavioral responses to the stereoisomers of amphetamine and methamphetamine

1995 • 375 citations

IMPROVEMENT IN MENTAL DEPRESSION WITH DECREASED THYROTROPIN RESPONSE AFTER ADMINISTRATION OF THYROTROPIN-RELEASING HORMONE

1972 • 374 citations

Automobile Accidents in Patients with Sleep Disorders

1989 • 355 citations

Modafinil Binds to the Dopamine Uptake Carrier Site with Low Affinity

1994 • 317 citations

The latency of activation of neurones in the lateral hypothalamus and substantia innominata during feeding in the monkey

1979 • 314 citations

Limbic cholinergic pathways involved in sleep and emotional behavior

1963 • 307 citations

Motor dyscontrol in narcolepsy: Rapid-eye-movement (REM) sleep without atonia and REM sleep behavior disorder

1992 • 302 citations

Nocturnal sleep of narcoleptics

1963 • 301 citations

Deprenyl is metabolized to methamphetamine and amphetamine in man.

1978 • 287 citations

Successful treatment of idiopathic hypersomnia and narcolepsy with modafinil

1988 • 271 citations

The Clinical Use of the Multiple Sleep Latency Test

1992 • 271 citations

Activity of mesencephalic dopamine and non-dopamine neurons across stages of sleep and waking in the rat

1983 • 265 citations

Hypnagogic and Hypnopompic Hallucinations: Pathological Phenomena?

1996 • 242 citations

Affective spectrum disorder: does antidepressant response identify a family of disorders with a common pathophysiology?

1990 • 241 citations

Life Effects of Narcolepsy in 180 Patients from North America, Asia and Europe Compared to Matched Controls

1981 • 231 citations

REM Sleep Induction by Physostigmine Infusion During Sleep

1976 • 230 citations

Treatment of Narcolepsy with γ-Hydroxybutyrate. A Review of Clinical and Sleep Laboratory Findings

1986 • 227 citations

Serotonin hyperpolarizes cholinergic low-threshold burst neurons in the rat laterodorsal tegmental nucleus in vitro.

1992 • 224 citations

Central α1-adrenergic stimulation in relation to the behaviour stimulating effect of modafinil; studies with experimental animals

1990 • 221 citations

Cataplectic-like behavior in cats after micro-injections of carbachol in pontine reticular formation

1974 • 221 citations

THE USE OF BENZEDRINE FOR THE TREATMENT OF NARCOLEPSY

1935 • 212 citations

Role of catecholamines in the modafinil and amphetamine induced wakefulness, a comparative pharmacological study in the cat

1992 • 207 citations

The Atonia and Myoclonia of Active (REM) Sleep

1990 • 207 citations

A new animal model of endogenous depression: A summary of present findings

1990 • 203 citations

Use of an automated external de fibrillation pacemaker by ambulance staff

1982 • 200 citations

DQB1*0602 and DQA1*0102 (DQ1) Are Better Markers Than DR2 for Narcolepsy in Caucasian and Black Americans

1994 • 200 citations

Criteria for the diagnosis of the narcoleptic syndrome.

1957 • 199 citations

EFFECT ON WEAKNESS AND SPASTICITY IN AMYOTROPHIC LATERAL SCLEROSIS OF THYROTROPIN-RELEASING HORMONE

1983 • 199 citations

Monoamine Oxidase Inhibitors

1996 • 195 citations

Gammahydroxybutyrate and Narcolepsy: A Double-Blind Placebo-Controlled Study

1993 • 188 citations

De la narcolepsie

1880 • 184 citations

Studies in Psychophysiology of Dreams

1960 • 181 citations

Enhancement of acetylcholine release during paradoxical sleep in the dorsal tegmental field of the cat brain stem

1990 • 175 citations

Excitatory action of TRH on spinal motoneurones

1977 • 171 citations

Disorders of Excessive Daytime Somnolence: Polygraphic and Clinical Data for 100 Patients

1981 • 169 citations

The imidazoline preferring receptor: binding studies in bovine, rat and human brainstem

1989 • 167 citations

Narcolepsy and Hypersomnia

1981 • 164 citations

The nature of the narcoleptic sleep attack

1966 • 163 citations

The Treatment of Narcolepsy-Cataplexy with Nocturnal Gamma-Hydroxybutyrate

1979 • 163 citations

Neuronal Activity in Narcolepsy: Identification of Cataplexy-Related Cells in the Medial Medulla

1991 • 162 citations

Narcolepsy in Children

1994 • 162 citations

A pharmacological model of paradoxical sleep: The role of cholinergic and monoamine systems

1970 • 162 citations

Modafinil: A Double-Blind Multicentric Study

1994 • 161 citations

Microinjection of neostigmine into the pontine reticular formation of cats enhances desynchronized sleep signs.

1984 • 160 citations

In vivo characterization of locally applied dopamine uptake inhibitors by striatal microdialysis

1990 • 159 citations

Mono-amine oxidase inhibitors, sleep and mood

1970 • 155 citations

Isolated Sleep Paralysis Elicited by Sleep Interruption

1992 • 152 citations

The clinical spectrum of narcolepsy and idiopathic hypersomnia

1996 • 147 citations

EVALUATION of SHORT-TERM and LONG-TERM TREATMENT of the NARCOLEPSY SYNDROME WITH CLOMIPRAMINE HYDROCHLORIDE

1976 • 146 citations

Effect of specific M1, M2 muscarinic receptor agonists on REM sleep generation

1989 • 145 citations

Physiology of REM sleep, cataplexy, and sleep paralysis.

1995 • 145 citations

The Effects of γ-Hydroxybutyrate on the Sleep of Narcolepsy Patients: A Double-Blind Study

1990 • 143 citations

Central nervous system stimulants

2000 • 143 citations

High Prevalence of Isolated Sleep Paralysis: Kanashibari Phenomenon in Japan

1987 • 141 citations

Paranoid Psychosis in Narcolepsy and the Possible Danger of Benzedrine Treatment

1938 • 140 citations

Narcolepsy and its treatment with stimulants. ASDA standards of practice.

1994 • 140 citations

Excessive Daytime Sleepiness and the Pathophysiology of Narcolepsy-Cataplexy: A Laboratory Perspective

1986 • 138 citations

NARCOLEPSY1

1934 • 136 citations

Evaluation of Treatment With Stimulants in Narcolepsy

1994 • 134 citations

The role of the raphe nuclei in the regulation of ponto-geniculo-occipital wave activity

1973 • 134 citations

Epidemiology of Narcolepsy

1994 • 134 citations

Psychosocial Impact of Narcolepsy

1994 • 134 citations

Ambulatory 24 hour sleep-wake monitoring in narcolepsy-cataplexy compared to matched controls

1988 • 132 citations

A Study on Cataplexy

1974 • 131 citations

Narcolepsy associated with lesions of the diencephalon

1989 • 129 citations

Twenty-four-hour recording in REM-narcoleptics with special reference to nocturnal sleep disruption.

1978 • 128 citations

IDIOPATHIC NARCOLEPSY: A DISEASE SUI GENERIS; WITH REMARKS ON THE MECHANISM OF SLEEP

1926 • 126 citations

Treatment of Narcolepsy with Methamphetamine

1993 • 125 citations

Histological and ultrastructural evidence thatd-amphetamine causes degeneration in neostriatum and frontal cortex of rats

1990 • 125 citations

Cholinergic and non-cholinergic projections from the rat basal forebrain revealed by combined choline acetyltransferase and Phaseolus vulgaris leucoagglutinin immunohistochemistry

1986 • 122 citations

Canine cataplexy is preferentially controlled by adrenergic mechanisms: evidence using monoamine selective uptake inhibitors and release enhancers

1993 • 121 citations

Narcolepsy and immunity

1995 • 119 citations

Tricyclic dose requirements across pregnancy

1993 • 119 citations

Muscarinic Cholinergic Receptors and the Canine Model of Narcolepsy

1986 • 119 citations

Treatment of Intractable Narcolepsy with a Monoamine Oxidase Inhibitor

1971 • 118 citations

Scheduled Naps in the Management of Daytime Sleepiness in Narcolepsy-Cataplexy

1993 • 116 citations

Altered states of consciousness in disorders of daytime sleepiness

1975 • 116 citations

The positive diagnosis of narcolepsy and narcolepsy's borderland

1993 • 116 citations

Extensive HLA class II studies in 58 non‐DRB1*15 (DR2) narcoleptic patients with cataplexy

1997 • 116 citations

HLA DR15 (DR2) and DQB1*0602 typing studies in 188 narcoleptic patients with cataplexy

1997 • 115 citations

Acute poisoning from gamma-hydroxybutyrate in California.

1992 • 112 citations

Brain tyrosine level controls striatal dopamine synthesis in haloperidol-treated rats

1977 • 112 citations

In-vivo measurements of tryptophan and tyrosine hydroxylase activities in mouse brain

1973 • 111 citations

235 cases of excessive daytime sleepiness

1977 • 108 citations

The physiological (EEG) nature of drowsiness and its relation to performance deficits in narcoleptics

1983 • 107 citations

Relative Efficacy of Drugs for the Treatment of Sleepiness in Narcolepsy

1991 • 105 citations

Efficacy of gamma-hydroxybutyrate versus placebo in treating narcolepsy-cataplexy: Double-blind subjective measures

1989 • 105 citations

Treatment of narcolepsy with Ritalin

1959 • 104 citations

Thalidomide in Human Immunodeficiency Virus (HIV) Patients

1992 • 102 citations

The carbachol-induced enhancement of desynchronized sleep signs is dose dependent and antagonized by centrally administered atropine

1989 • 100 citations

The effects and effectiveness of gamma-hydroxybutyrate in patients with narcolepsy.

1985 • 99 citations

Narcolepsy

1990 • 98 citations

Effects of nocturnal gamma-hydroxybutyrate on sleep/waking patterns in narcolepsy-cataplexy.

1980 • 97 citations

Electrophysiological Studies of the Functions of the Nucleus Basalis in Primates

1991 • 97 citations

Clinical Features of Narcolepsy: Japanese Experiences

1988 • 97 citations

The time-dependent induction of REM sleep and arousal by physostigmine infusion during normal human sleep

1977 • 96 citations

Comparison of the Psychosocial Effects of Epilepsy and Narcolepsy/Cataplexy: A Controlled Study

1984 • 95 citations

Genetic Factors in Canine Narcolepsy

1978 • 95 citations

Importance of duration of drug action in the antagonism of p-chloroamphetamine depletion of brain serotonin—comparison of fluoxetine and chlorimipramine

1978 • 95 citations

Muscle atonia is triggered by cholinergic stimulation of the basal forebrain: implication for the pathophysiology of canine narcolepsy

1995 • 95 citations

Cholinergic mechanisms and cataplexy in dogs

1979 • 95 citations

Treatment of Narcolepsy: Objective Studies on Methylphenidate, Pemoline, and Protriptyline

1986 • 94 citations

Effects of Modafinil on Symptomatology of Human Narcolepsy

1993 • 94 citations

Canine model of narcolepsy: Genetic and developmental determinants

1982 • 93 citations

Selegiline in the treatment of narcolepsy

1994 • 92 citations

Catecholamines and the sleep-wake cycle II. REM sleep

1983 • 92 citations

Short-Term Triazolam Use Improves Nocturnal Sleep of Narcoleptics

1992 • 91 citations

Controlled trial of thyrotropin releasing hormone tartrate in ataxia of spinocerebellar degenerations

1983 • 90 citations

Local administration of dopaminergic drugs into the ventral tegmental area modulates cataplexy in the narcoleptic canine

1996 • 90 citations

Genetic linkage of autosomal recessive canine narcolepsy with a mu immunoglobulin heavy-chain switch-like segment.

1991 • 89 citations

Florid Refractory Schizophrenias That Turn Out to Be Treatable Variants of HLA-Associated Narcolepsy

1991 • 89 citations

NARCOLEPSY AND OTHER DISTURBANCES IN THE SLEEP-WAKING RHYTHM

1963 • 88 citations

Pharmacotherapy in narcolepsy.

1960 • 88 citations

Dose‐dependent effects of the 5‐HT_1A receptor agonist 8‐OH‐DPAT on sleep and wakefulness in the rat

1992 • 87 citations

Sleep Apnea in Narcolepsy

1986 • 86 citations

Daytime Sleepiness and Daytime Wakefulness: The Effect of Instruction

1982 • 85 citations

Venlafaxine: A Structurally Unique and Novel Antidepressant

1995 • 84 citations

Dopamine D2 mechanisms in canine narcolepsy

1991 • 83 citations

Narcolepsy: Cholinergic receptor changes in an animal model

1984 • 82 citations

Sleep Paralysis

1962 • 82 citations

Comparative effects of modafinil and amphetamine on daytime sleepiness and cataplexy of narcoleptic dogs.

1995 • 82 citations

Sleep studies on canine narcolepsy: Pattern and cycle comparisons between affected and normal dogs

1977 • 82 citations

Study of HLA class II alleles by PCR oligotyping in leprosy patients from North India

1993 • 81 citations

NATURAL HISTORY, SYMPTOMS AND TREATMENT OF THE NARCOLEPTIC SYNDROME

1975 • 81 citations

Tests of Memory in Narcoleptics

1990 • 79 citations

Ventral root depolarization and spinal reflex augmentation by a TRH analog in rat spinal cord

1982 • 79 citations

Treatment of narcolepsy with imipramine (Tofranil) and desmethylimipramine (Pertofran)

1966 • 79 citations

Effects of several centrally active drugs on the sleep-wakefulness cycle of cats

1979 • 79 citations

Induction and Resetting of REM Sleep Rhythm in Normal Man by Arecholine: Blockade by Scopolamine

1978 • 78 citations

Desmethyl Metabolites of Serotonergic Uptake Inhibitors Are More Potent for Suppressing Canine Cataplexy Than Their Parent Compounds

1993 • 78 citations

Further studies on the prevalence of isolated sleep paralysis in black subjects.

1986 • 77 citations

3. The Treatment of Excessive Somnolence With Stimulant Drugs

1993 • 77 citations

Narcolepsy-cataplexy in a female dog

1974 • 76 citations

Excretion of Psychoactive Drugs into Breast Milk

1994 • 75 citations

Effect of modafinil and amphetamine on the rat catecholaminergic neuron activity

1991 • 75 citations

Motor dyscontrol in sleep of narcoleptic patients (a lifelong development?)

1993 • 75 citations

Retrograde labeling of neurons in the brain stem following injections of [3H]choline into the forebrain of the rat

1987 • 75 citations

Amphetamine secretion in breast milk

1984 • 74 citations

Amphetamine secretion in breast milk

1984 • 74 citations

Life Effects of Narcolepsy: Relationships to Geographic Origin (North American, Asian or European) and to Other Patient and Illness Variables

1983 • 73 citations

Catecholamines and the sleep-wake cycle I. EEG and behavioral arousal

1982 • 73 citations

Selegeline Hydrochloride Treatment in Narcolepsy. A Double-Blind, Placebo-Controlled Study

1995 • 73 citations

The nature of sleep attack and other symptoms of narcolepsy

1968 • 72 citations

Sleep paralysis

1993 • 72 citations

Neurochemical perspectives to the function of monoamine oxidase

1989 • 72 citations

Simultaneous recording of substantia nigra neurons and voltammetric release of dopamine in the caudate of behaving cats

1985 • 71 citations

Breastfeeding and the use of psychotropic medication: a review

1990 • 71 citations

The Effects of L-Dopa on Periodic Leg Movements and Sleep Organization in Narcolepsy

1989 • 71 citations

Longitudinal studies of the effect of monoamine oxidase inhibitors on sleep in man

1969 • 70 citations

Heterozygosity at the canarc-1 locus can confer susceptibility for narcolepsy: induction of cataplexy in heterozygous asymptomatic dogs after administration of a combination of drugs acting on monoaminergic and cholinergic systems

1993 • 70 citations

Clinical Pharmacology of Monoamine Oxidase Inhibitors

1986 • 69 citations

Narcolepsy-Cataplexy

1982 • 69 citations

Evidence for the existence of a homogenous population of imidazoline receptors in the human brainstem

1988 • 67 citations

1. Amphetamines and Narcolepsy: Use of the Stanford Database

1993 • 66 citations

Protriptyline: an effective agent in the treatment of the narcolepsy- cataplexy syndrome and hypersomnia

1977 • 65 citations

Distribution of norepinephrine, epinephrine, dopamine, serotonin, 3,4-dihydroxyphenylacetic acid, homovanillic acid and 5-hydroxyindole-3-acetic acid in dog brain

1982 • 65 citations

Controversies in the Diagnosis of Narcolepsy

1994 • 65 citations

Practice Parameters for the Use of Stimulants in the Treatment of Narcolepsy

1994 • 64 citations

Cholinergic mechanisms in canine narcolepsy—I. Modulation of cataplexy via local drug administration into the pontine reticular formation

1994 • 63 citations

Response of dopaminergic neurons in cat to auditory stimuli presented across the sleep-waking cycle

1983 • 61 citations

Nocturnal REM Latency and Sleep Disturbance in Narcolepsy

1984 • 61 citations

Daytime performance deficits and physiological vigilance in untreated patients with narcolepsy-cataplexy compared to controls

1981 • 61 citations

Narcolepsy in a dog and a cat.

1973 • 60 citations

REM sleep suppression induced by selective monoamine oxidase inhibitors

1982 • 60 citations

Chapter 17 Neurotransmitter receptors and ionic conductances regulating the activity of neurones in substantia nigra pars compacta and ventral tegmental area

1993 • 59 citations

Dopaminergic transmission and the sleep-wakefulness continuum in man

1990 • 59 citations

Deprenyl as Symptomatic Therapy in Parkinsonʼs Disease

1988 • 58 citations

Alerting Effects of Naps in Patients with Narcolepsy

1986 • 58 citations

The neurobiology of narcolepsy-cataplexy

1993 • 58 citations

Narcolepsy in children.

1960 • 55 citations

Fluvoxamine and clomipramine in the treatment of cataplexy.

1980 • 55 citations

Sleepiness and performance in narcolepsy

1996 • 55 citations

Cytokine Regulation of Disease Progression in Leprosy and Tuberculosis

1994 • 54 citations

Neuropharmacology and Neurochemistry of Canine Narcolepsy

1994 • 54 citations

Role of central alpha-1 adrenoceptors in canine narcolepsy.

1988 • 54 citations

Effects of bromocriptine on periodic limb movements in human narcolepsy

1993 • 53 citations

Brain dopamine receptor levels elevated in canine narcolepsy

1987 • 53 citations

Sleep satiation in narcoleptic patients

1976 • 53 citations

Diflunisal‐induced maternal anemia as a cause of teratogenicity in rabbits

1984 • 52 citations

Compliance With Stimulant Medications in Patients with Narcolepsy

1997 • 52 citations

Treatment of Cataplexy With Clomipramine

1975 • 52 citations

Further characterization of the alpha-1 receptor subtype involved in the control of cataplexy in canine narcolepsy.

1993 • 52 citations

Therapeutic Effects of Mazindol on Narcolepsy

1986 • 52 citations

Cholinergic agonist-antagonist interactions on neocortical and limbic EEG activation

1967 • 52 citations

5-HT1-like receptor agonists enhance wakefulness

1992 • 51 citations

Effect of α1-adrenoceptors blockade with prazosin in canine narcolepsy

1988 • 51 citations

Exacerbation of Human Cataplexy by Prazosin

1989 • 50 citations

Activity of medial mesopontine units during cataplexy and sleep-waking states in the narcoleptic dog

1992 • 49 citations

Narcolepsy

1960 • 49 citations

Pontine lesions in idiopathic narcolepsy

1996 • 49 citations

REM sleep and NREM sleep in narcolepsy and hypersomnia

1969 • 48 citations

Physiological Sleep Tendency and Ability to Maintain Alertness at Night

1989 • 48 citations

Effects of imipramine, chlorimipramine, and fluoxetine on cataplexy in dogs

1976 • 48 citations

Viloxazine Hydrochloride in Narcolepsy: A Preliminary Report

1986 • 47 citations

Monoaminergic mechanisms and experimental cataplexy

1981 • 47 citations

The treatment of accessory symptoms in narcolepsy: a double-blind cross-over study of a selective serotonin re-uptake inhibitor (femoxetine) versus placebo

2009 • 47 citations

Effects of central alpha-2 adrenergic compounds on canine narcolepsy, a disorder of rapid eye movement sleep.

1990 • 47 citations

Sleep Fragmentation in Canine Narcolepsy

1986 • 46 citations

Levo(-) amphetamine and dextro(+) amphetamine in the treatment of narcolepsy

1973 • 46 citations

Cholinergic mechanisms in canine narcolepsy—II. Acetylcholine release in the pontine reticular formation is enhanced during cataplexy

1994 • 46 citations

Stability of Cataplexy Over Several Months—Information for the Design of Therapeutic Trials

1994 • 46 citations

EFFECT OF PHENELZINE AND SOME RELATED COMPOUNDS ON PREGNANCY AND ON SEXUAL DEVELOPMENT

1964 • 46 citations

2. Amphetamine Prescription

1993 • 45 citations

Fluoxetine for Isolated Sleep Paralysis

1993 • 44 citations

Selegiline in Narcolepsy

1986 • 44 citations

REM sleep and NREM sleep in narcolepsy and hypersomnia.

1969 • 44 citations

Life Effects of Narcolepsy

2008 • 44 citations

Treatment of Narcolepsy with Codeine

1986 • 43 citations

Psychiatric Morbidity in Narcoleptics on Chronic High Dose Methylphenidate Therapy

1995 • 42 citations

Eigenthümliche mit Einschlafen verbundene Anfälle

1892 • 42 citations

Course of Psychiatric Disorders in Pregnancy

1994 • 41 citations

Sleep cycle organization in narcoleptic and normal dogs

1979 • 41 citations

Comparative Effects of Modafinil and Amphetamine on Daytime Sleepiness and Cataplexy of Narcoleptic Dogs

1995 • 40 citations

Depression in narcolepsy and hypersomnia.

1977 • 40 citations

Chapter 47: Acetylcholine as a brain state modulator: triggering and long-term regulation of REM sleep

1993 • 40 citations

Effets du modafinil (300 mg) sur le sommeil, la somnolence et la vigilance du narcoleptique

1993 • 40 citations

Baseline sleep-wake patterns in the pointer dog

1977 • 40 citations

Patterns of Sleep and Wakefulness in Treated Narcoleptic Subjects

1994 • 40 citations

Nocturnal gamma-hydroxybutyrate. Effect on periodic leg movements and sleep organization of narcoleptic patients.

1989 • 39 citations

The effects of L‐dopa on excessive daytime sleepiness in narcolepsy

1991 • 39 citations

Ritanserin, A 5-HT2 Receptor Blocker, as Add-on Treatment in Narcolepsy

1991 • 39 citations

Problems and Coping Strategies Identified by Narcoleptic Patients

1984 • 39 citations

Daytime Sleep Characteristics and their Relationships with Night Sleep in the Narcoleptic Patient

1986 • 38 citations

An Alternative to the Multiple Sleep Latency Test for Determining Sleepiness in Narcolepsy and Hypersomnia: Polygraphic Score of Sleepiness

1986 • 38 citations

Controlled cross-over study of a 5-HT uptake inhibiting and an NA uptake inhibiting antidepressant.

1981 • 37 citations

Nocturnal γ-Hydroxybutyrate

1989 • 37 citations

Relative potencies of d- and l-amphetamine on the release of dopamine from cat brain in vivo.

1974 • 37 citations

Narcolepsy associated with primary temporal lobe B-cells lymphoma in a HLA DR2 negative subject.

1992 • 37 citations

Central α1 adrenoceptor subtypes in narcolepsy-cataplexy: a disorder of REM sleep

1989 • 36 citations

Serotoninergic Reuptake Mechanisms in the Control of Cataplexy

1986 • 36 citations

5-HT receptor agonists 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and 8-OH-DPAT increase wakefulness in the rat

1990 • 35 citations

Forty-Eight-Hour Polysomnographic Evaluation of Narcolepsy

1986 • 35 citations

[3H]Nisoxetine binding sites in the cat brain: An autoradiographic study

1995 • 35 citations

Modafinil in Diurnal Sleepiness. A Study of 123 Patients

1994 • 34 citations

Familial sleep paralysis.

1968 • 33 citations

Evidence for excessive sleepiness in canine narcoleptics

1986 • 32 citations

Controlled cross‐over study of a 5‐HT uptake inhibiting and an NA uptake inhibiting antidepressant

1981 • 32 citations

Selective suppression of rapid eye movement sleep (REMS) in cats by typical and atypical antidepressants.

1982 • 31 citations

Epileptoide Schlafzustände

1878 • 31 citations

Cholinergic Regulation of Cataplexy in Canine Narcolepsy in the Pontine Reticular Formation is Mediated by M2 Muscarinic Receptors

1994 • 29 citations

Narcolepsy in seven dogs.

1976 • 28 citations

Interactions between reserpine and various compounds on the accumulation of [14C] 5-hydroxytryptamine and [3H] noradrenaline in homogenates from rat hypothalamus

1979 • 27 citations

Immunological Features of Narcolepsy in Japan

1988 • 27 citations

Sleepiness after glucose in narcolepsy

1994 • 27 citations

Narcolepsy and cataplexy. Clinical features, treatment and cerebrospinal fluid findings.

1974 • 27 citations

Eating and its Relationships with Subjective Alertness and Sleep in Narcoleptic Subjects Living without Temporal Cues

1990 • 26 citations

A comparison of thalidomide and pentobarbital - new methods for identifying novel hypnotic drugs.

1977 • 26 citations

Effects of SDZ NVI-085, a putative subtype-selective α1-agonist, on canine cataplexy, a disorder of rapid eye movement sleep

1991 • 24 citations

Sleep onset rapid‐eye‐movement episodes in narcolepsy: REM sleep pressure or nonREM‐REM sleep dysregulation?

1992 • 23 citations

Bright white light does not improve narcoleptic symptoms

1989 • 22 citations

REM Changes in Narcolepsy With Selegiline

1995 • 22 citations

The action of tricyclics (alone or in combination with methylphenidate) upon several symptoms of narcolepsy

1977 • 21 citations

NARCOLEPTIC SYNDROME AND PARADOXICAL SLEEP

1966 • 21 citations

Central administration of yohimbine increases free 3-methoxy-4-hydroxyphenylglycol in the cerebrospinal fluid of the rat

1982 • 21 citations

Propranolol: Long-Term Treatment in Narcolepsy-Cataplexy

1985 • 21 citations

Thalidomide, a hypnotic with immune modulating properties, increases cataplexy in canine narcolepsy

1996 • 21 citations

Successful Treatment of Narcolepsy With Propranolol

1979 • 20 citations

Love potion number 8 1/2. Gamma-hydroxybutyrate poisoning.

1993 • 20 citations

Treatment of narcolepsy‐cataplexy syndrome with the new selective and reversible MAO‐A inhibitor brofaromine—a pilot study

1993 • 20 citations

TREATMENT OF NARCOLEPSY WITH L-TYROSINE

1988 • 19 citations

Biochemical Effects of Antidepressants in Animals

1980 • 18 citations

HLA in Disorders of Excessive Daytime Sleepiness Without Cataplexy in Canada

1988 • 17 citations

Effects of protriptyline on vigilance and information processing in narcolepsy

1988 • 17 citations

Electroencephalographic analyses of amphetamine and its methoxy derivatives with reference to their sites of EEG alerting in the rabbit brain

1969 • 17 citations

The multiple sleep latency test: a paradoxical test?

1992 • 17 citations

Zur Narkolepsiefrage.

1915 • 16 citations

Occurrence of Neuroleptic Malignant Syndrome in a Narcoleptic Patient

1983 • 16 citations

[Follow-up of 151 pregnant women exposed to antidepressant treatment (MAOI excluded) during organogenesis].

1994 • 16 citations

Signs and symptoms associated with cataplexy in narcolepsy patients

1990 • 16 citations

Narcolepsy, Paranoid Psychosis, Major Depression, and Tardive Dyskinesia

1984 • 16 citations

HLA in Narcolepsy in Canada

1988 • 15 citations

Über das Auftreten von halluzinatorisch-kataplektischem Angstsyndrom, Wachanfällen und ähnlichen Störungen bei Schizophrenen

1939 • 14 citations

Methysergide in the Treatment of Narcolepsy

1975 • 14 citations

Narcolepsy and Cataplexy. Clinical Features, Treatment and Cerebrospinal Fluid Findings

1974 • 14 citations

TREATMENT OF NARCOLEPSY WITH L-TYROSINE: DOUBLE-BLIND PLACEBO-CONTROLLED TRIAL

1989 • 13 citations

Preliminary clinical trial with L-DOPA in narcolepsy

1971 • 13 citations

The Urinary Output of Catecholamines in Narcolepsy Under Resting Conditions and Following Administration of Dopamine, Dopa, and Dops

1966 • 12 citations

Acute mood improvement after dextroamphetamine and methylphenldate in narcolepsy

1995 • 12 citations

Effects of l-tyrosine on mixed-acting sympathomimetic-induced pressor actions

1992 • 12 citations

Dynamic Suppression of REM Sleep by Parenteral Administration of the Serotonin-1 Agonist Eltoprazine

1992 • 12 citations

Narcolepsy in a 2‐Year‐Old Boy

1996 • 12 citations

Effects of Bromocriptine in Human Narcolepsy

1993 • 11 citations

Effects of thyrotropin-releasing hormone and its analogue L-6-ketopiperidine-2-carbonyl-leucyl-L-prolin-amide on behaviour and electroencephalogram.

1988 • 10 citations

Critical Notes on The Specificity of Drugs in The Study of Metabolism and Functions of Brain Monoamines

1988 • 10 citations

The Effect of Behavioral Stimulant Doses of Amphetamine on Blood Pressure

1976 • 10 citations

Tranylcypromine in Narcolepsy

1995 • 9 citations

ORAL 5-HYDROXYTRYPTOPHAN EFFECTS ON SLEEP

1973 • 9 citations

Blood pressure and heart rate responses produced by d-amphetamine: correlation with blood levels of drug.

1978 • 9 citations

Disorders of Excessive Daytime Sleepiness Without Cataplexy, and Their Relationship with HLA in Japan

1988 • 8 citations

Effects of thalidomide and pentobarbital on neuronal activity in the preoptic area during sleep and wakefulness in the cat

1985 • 8 citations

HLA DR2 in narcolepsy with sleep-onset REM periods but not cataplexy

1991 • 8 citations

Effectiveness of Yohimbine in Treating Narcolepsy

1994 • 8 citations

Carbamazepine as a Treatment for Cataplexy

1996 • 7 citations

Efficacy of Trazodone in Narcolepsy

1985 • 6 citations

[Narcolepsy and the psychiatric tableau. A specific form of narcolepsy?].

1992 • 6 citations

Effects of clonidine in narcolepsy.

1985 • 6 citations

Personality traits in patients with narcolepsy

1981 • 6 citations

Trial with amantadine in narcolepsy

1973 • 5 citations

HLA in Narcolepsy/Cataplexy in the United Kingdom

1988 • 5 citations

Treatment of sleep disorders II: narcolepsy.

1983 • 5 citations

Diagnostic de la narcolepsie-cataplexie: intérêt de l'enregistrement continu sous EEG ambulatoire. À propos de 20 observations

1995 • 5 citations

Drugs for cataplexy

1982 • 4 citations

HLA Antigens in 206 Japanese Patients with Narcolepsy and 46 Patients with Essential Hypersomnia

1989 • 4 citations

Treatment of Narcolepsy with Mono-Amino-Oxidase Inhibitors and Sympathomimetic Agents

1970 • 4 citations

[L-dopa therapy of narcolepsy. Observation of clinical course and polygraphic EEG night sleep and day leads].

1973 • 4 citations

The treatment of narcolepsy and cataplexy.

1985 • 3 citations

NARCOLEPSY AND NEUROSIS

1973 • 3 citations

Gammahydroxybutyrate in narcolepsy.

1992 • 3 citations

The effect of naloxone on the symptoms of narcolepsy.

1989 • 3 citations

The Treatment of Sleep Disorders

1984 • 2 citations

Therapeutic Usefulness of Ergotamine Tartrate for Narcolepsy

1978 • 2 citations

Arousal and personality traits: Effects of central stimulants in narcolepsy

1987 • 2 citations

Effect of the thyrotropin-releasing hormone analogue on an electrographic picture of sleep

1988 • 2 citations