Narcolepsy and immunity

HLA and Disease Associations

1985 • 893 citations

Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

1992 • 763 citations

The class II molecules of the human and murine major histocompatibility complex

1984 • 664 citations

Autoantibodies to GABA-ergic Neurons and Pancreatic Beta Cells in Stiff-Man Syndrome

1990 • 618 citations

Inflammatory cytokines within the central nervous system: sources, function, and mechanism of action

1992 • 614 citations

The Cholinergic Neuronal Differentiation Factor from Heart Cells Is Identical to Leukemia Inhibitory Factor

1989 • 557 citations

TRANSFER OF ALLERGIC ENCEPHALOMYELITIS IN RATS BY MEANS OF LYMPH NODE CELLS

1960 • 540 citations

MHC Class-II Molecules and Autoimmunity

1991 • 521 citations

Autoimmune Diseases: The Failure of Self Tolerance

1990 • 495 citations

Advances in Sleep Research.

1974 • 320 citations

A neuronal group theory of sleep function

1993 • 308 citations

HUMAN CLASS II MAJOR HISTOCOMPATIBILITY COMPLEX GENES AND PROTEINS

1988 • 277 citations

Animal models

1994 • 276 citations

Nomenclature for Factors of the HLA System, 1994

1994 • 219 citations

Sleep-promoting effects of muramyl peptides.

1982 • 216 citations

The prevalence of narcolepsy: An epidemiological study of the Finnish Twin Cohort

1994 • 213 citations

GENETIC MARKERS IN NARCOLEPSY

1984 • 212 citations

DQB1*0602 and DQA1*0102 (DQ1) Are Better Markers Than DR2 for Narcolepsy in Caucasian and Black Americans

1994 • 200 citations

DNA typing of HLA Class II genes in B‐lymphoblastoid cell lines homozygous for HLA

1992 • 197 citations

Immunobiology of HLA

1989 • 175 citations

On the HLA‐DQ(α1*0501, β1*0201)‐associated susceptibility in celiac disease: A possible gene dosage effect of DQB1*0201

1993 • 171 citations

Involvement of cytokines in acute neurodegeneration in the CNS

1993 • 169 citations

Narcolepsy and Hypersomnia

1981 • 164 citations

Brain mechanisms of sleep

1985 • 142 citations

Narcolepsy and Hypersomnia

1981 • 140 citations

FAMILIAL PATTERNS OF NARCOLEPSY

1989 • 137 citations

Narcolepsy associated with lesions of the diencephalon

1989 • 129 citations

What is the basis for HLA-DQ associations with autoimmune disease?

1991 • 127 citations

Posttraumatic excessive daytime sleepiness

1983 • 118 citations

IgG heavy chain allotypes (Gm) in autoimmune diseases.

1980 • 102 citations

Posttraumatic Narcolepsy in Mild to Moderate Closed Head Injury

1994 • 97 citations

HLA AND DISEASE ASSOCIATIONS

1984 • 96 citations

HLA antigens in narcolepsy

1987 • 90 citations

Genetic linkage of autosomal recessive canine narcolepsy with a mu immunoglobulin heavy-chain switch-like segment.

1991 • 89 citations

BRAIN MECHANISMS OF SLEEP

1984 • 82 citations

Amyotrophic lateral sclerosis: An unconventional autoimmune disease?

1989 • 77 citations

HLA class II haplotypes in Amerindians and in black North and South Americans*

1991 • 70 citations

Heterozygosity at the canarc-1 locus can confer susceptibility for narcolepsy: induction of cataplexy in heterozygous asymptomatic dogs after administration of a combination of drugs acting on monoaminergic and cholinergic systems

1993 • 70 citations

Narcolepsy-Cataplexy

1982 • 69 citations

MHC class II sequences of an HLA-DR2 narcoleptic

1988 • 68 citations

HLA and narcolepsy in a German population

1986 • 67 citations

BMT in experimental autoimmune diseases.

1993 • 67 citations

Clinical and Sleep laboratory study of narcoleptic symptoms in multiple sclerosis

1987 • 67 citations

Multiple sclerosis and narcolepsy/cataplexy in a monozygotic twin

1980 • 67 citations

Major Histocompatibility.Complex Molecule Expression in the Human Central Nervous System: Immunohistochemical Analysis of 40 Patients

1988 • 65 citations

CSF immune variables in patients with narcolepsy

2009 • 63 citations

Immune Factors in Narcolepsy

1986 • 60 citations

Brain neurotransmitter changes in human narcolepsy

1992 • 59 citations

The neurobiology of narcolepsy-cataplexy

1993 • 58 citations

Molecular Basis of Human Leukocyte Antigen Class II

1990 • 58 citations

Multiple Sclerosis and narcolepsy

1991 • 56 citations

Nomenclature for factors of the HLA system, 1994

1994 • 56 citations

Neuroimmunology

1990 • 55 citations

Mechanisms of Cell Adhesion in the Nervous System: Role of the Immunoglobulin Gene Superfamily

1989 • 50 citations

Familial Multiple Sclerosis Associated With Narcolepsy

1966 • 48 citations

HLA-DR2 association with excessive somnolence in narcolepsy does not generalize to sleep apnea and is not accompanied by systemic autoimmune abnormalities

1988 • 48 citations

Possible association between HLA‐B7 and narcolepsy

1984 • 45 citations

Genetics and multiple sclerosis: An overview

1994 • 41 citations

Extensive Polymorphism of a (CA)n Microsatellite Located in the HLA-DQA1/DQB1 Class II Region

1995 • 39 citations

Monozygotic twins concordant for the narcoleptic syndrome

1989 • 39 citations

Narcolepsy associated with primary temporal lobe B-cells lymphoma in a HLA DR2 negative subject.

1992 • 37 citations

Neurochemical Studies of Human Narcolepsy: Alpha-Adrenergic Receptor Autoradiography of Human Narcoleptic Brain and Brainstem

1994 • 36 citations

Molecular Immunobiology of Self-reactivity

1993 • 35 citations

Narcolepsy: A Neuropathologic Study

1986 • 34 citations

Polymorphism in the upstream regulatory region of DQA1 genes and DRB1, QAP, DQA1, and DQB1 haplotypes in the German population

1994 • 33 citations

Chronic infections and autoimmunity.

1991 • 32 citations

Genetically Determined Animal Models of Narcolepsy, A Disorder of REM Sleep

1992 • 31 citations

NARCOLEPSY IN IDENTICAL TWINS

1961 • 30 citations

Narcolepsy without unique MHC class II antigen association: Studies in the canine model

1989 • 30 citations

No difference in the nucleotide sequence of the DQß ß1 domain between narcoleptic and healthy individuals with DR2,Dw2

1989 • 29 citations

Posttraumatic narcolepsy: the complete syndrome with tissue typing

1989 • 27 citations

DR2-Positive Monozygotic Twins Discordant for Narcolepsy

1990 • 27 citations

Narcolepsy in monozygotic twins

1987 • 27 citations

DQB1-0602 (DQw1) Is Not Present in Most NonDR2 Caucasian Narcoleptics

1992 • 27 citations

The contribution of non-MHC genes to susceptibility to autoimmune diseases

1991 • 25 citations

The mosaic of autoimmunity : (the factors associated with autoimmune disease )

1989 • 23 citations

Post-traumatic Narcolepsy

1987 • 23 citations

HLA 1991 : proceedings of the Eleventh International Histocompatibility Workshop and Conference, held in Yokohama, Japan, 6-13 November, 1991

1992 • 19 citations

Unilateral cataplexy associated with systemic lupus erythematosus

1976 • 16 citations

Narcolepsy: a family study.

1979 • 16 citations

Restriction fragment length polymorphism in canine narcolepsy

1989 • 15 citations

Genetic analysis of susceptibility to Type 1 diabetes

1992 • 15 citations

HLA in Narcolepsy in Canada

1988 • 15 citations

[HLA and narcolepsy].

1986 • 14 citations

HLA class II-restricted binding of muramyl peptides to B lymphocytes of normal and narcoleptic subjects

1990 • 14 citations

Narcolepsy in systemic lupus erythematosus.

1993 • 13 citations

A new DRB1 * 1202 allele (DRB1 * 12022) found in association with DQA1 * 0102 and DQB1 * 0602 in two Black narcoleptic subjects

1995 • 12 citations

The Mosaic of Autoimmunity. The Factors Associated with Autoimmune Disease

1990 • 12 citations

Familial narcolepsy in Finland

1991 • 12 citations

Human DNA sequences isolated with an immunoglobulin switch region probe: sequence, chromosomal localization, and restriction fragment length polymorphisms

1986 • 8 citations

Narcolepsy and HLA in the Federal Republic of Germany: Population and Family Data

1988 • 8 citations

A deletion in the second exon of an HLA-DRB1 Allele found in a DR2-negative narcolepsy patient

1993 • 8 citations

Immune Factors in Narcolepsy in the United Kingdom

1988 • 7 citations

Genetic Markers in Familial Narcolepsy

1991 • 4 citations

HLA Antigens in 206 Japanese Patients with Narcolepsy and 46 Patients with Essential Hypersomnia

1989 • 4 citations

Ir genes: towards the year 2000

1991 • 2 citations

Ernst Klenk Lecture, November 1987. Molecular studies in neuroscience: implications for medicine.

1991 • 1 citations