Prolactin recruits STAT1, STAT3 and STAT5 independent of conserved receptor tyrosines TYR402, TYR479, TYR515 and TYR580

Cytokine signal transduction

1994 • 1,358 citations

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

1993 • 1,223 citations

Choice of STATs and Other Substrates Specified by Modular Tyrosine-Based Motifs in Cytokine Receptors

1995 • 992 citations

Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

1995 • 956 citations

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav.

1994 • 886 citations

An Interleukin-4-Induced Transcription Factor: IL-4 Stat

1994 • 856 citations

Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.

1995 • 641 citations

Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription.

1994 • 599 citations

Requirement of Serine Phosphorylation for Formation of STAT-Promoter Complexes

1995 • 578 citations

Cloning and expression of the rat prolactin receptor, a member of the growth hormone/prolactin receptor gene family

1988 • 564 citations

Requirement for MAP Kinase (ERK2) Activity in Interferon α- and Interferon β-Stimulated Gene Expression Through STAT Proteins

1995 • 549 citations

Contribution of STAT SH2 Groups to Specific Interferon Signaling by the Jak-STAT pathway

1995 • 428 citations

The alphas, betas, and kinases of cytokine receptor complexes

1993 • 418 citations

Tyrosine Phosphorylation of DNA Binding Proteins by Multiple Cytokines

1993 • 367 citations

Activation of receptor-associated tyrosine kinase JAK2 by prolactin.

1994 • 354 citations

The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains.

1991 • 297 citations

Role of STAT2 in the Alpha Interferon Signaling Pathway

1995 • 280 citations

Expression of prolactin and prolactin receptor in human breast carcinoma. Evidence for an autocrine/paracrine loop.

1995 • 255 citations

The Growth Hormone/Prolactin Receptor Family

1993 • 227 citations

Prolactin-induced proliferation of Nb2 cells involves tyrosine phosphorylation of the prolactin receptor and its associated tyrosine kinase JAK2.

1994 • 226 citations

Interleukin 2 and erythropoietin activate STAT5/MGF via distinct pathways.

1995 • 224 citations

Transcriptional Regulation by the Helix Bundle Peptide Hormones: Growth Hormone, Prolactin, and Hematopoietic Cytokines

1994 • 221 citations

A prolactin-dependent immune cell line (Nb2) expresses a mutant form of prolactin receptor.

1991 • 186 citations

Proline-rich Sequence-mediated Jak2 Association to the Prolactin Receptor Is Required but Not Sufficient for Signal Transduction

1995 • 172 citations

Growth signaling and JAK2 association mediated by membrane-proximal cytoplasmic regions of prolactin receptors

1994 • 144 citations

Prolactin receptor triggering. Evidence for rapid tyrosine kinase activation.

1992 • 137 citations

JAK2 activation and cell proliferation induced by antibody-mediated prolactin receptor dimerization.

1994 • 127 citations

Interferon gamma rapidly induces in human monocytes a DNA-binding factor that recognizes the gamma response region within the promoter of the gene for the high-affinity Fc gamma receptor.

1992 • 114 citations

A single phosphotyrosine residue of the prolactin receptor is responsible for activation of gene transcription.

1995 • 113 citations

Prolactin activates Ras via signaling proteins SHC, growth factor receptor bound 2, and son of sevenless.

1995 • 105 citations

Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor β-chain

1995 • 92 citations

Effects of growth hormone and prolactin immune development and function

1995 • 90 citations

Intracellular Tyrosine Residues of the Human Growth Hormone Receptor Are Not Required for the Signaling of Proliferation or Jak-STAT Activation

1995 • 86 citations

Prolactin activates the interferon-regulated p91 transcription factor and the Jak2 kinase by tyrosine phosphorylation.

1994 • 81 citations

Receptor to nucleus signaling by prolactin and interleukin 2 via activation of latent DNA-binding factors.

1994 • 70 citations

Hormonal regulation of transcription factor activity in mammary epithelial cells

1994 • 58 citations

The mammary factor MPBF is a prolactin‐induced transcriptional regulator which binds to STAT factor recognition sites

1994 • 53 citations

Protein tyrosine phosphorylation as a mechanism which regulates cytokine activation of early response genes

1995 • 53 citations

Mapping of the Cytoplasmic Domain of the Human Growth Hormone Receptor Required for the Activation of Jak2 and Stat Proteins

1995 • 49 citations

The Rabbit Mammary Gland Prolactin Receptor Is Tyrosine-phosphorylated in Response to Prolactin in Vivo and in Vitro

1995 • 45 citations

A limited cytoplasmic region of the prolactin receptor critical for signal transduction

1994 • 39 citations

Culture of human monocytes with granulocyte-macrophage colony-stimulating factor results in enhancement of IFN-gamma receptors but suppression of IFN-gamma-induced expression of the gene IP-10.

1993 • 36 citations

Prolactin activates Ras via signaling proteins SHC, growth factor receptor bound 2, and son of sevenless

1995 • 32 citations

Prolactin induces rapid p95/p70 tyrosine phosphorylation, and protein binding to GAS-like sites in the anx Icp35 and c-fos genes.

1994 • 24 citations

Involvement of JAK-family tyrosine kinases in hematopoietin receptor signal transduction

1994 • 13 citations

Prolactin induces rapid p95/p70 tyrosine phosphorylation, and protein binding to GAS-like sites in the anx Icp35 and c-fos genes

1994 • 6 citations