Intracellular Tyrosine Residues of the Human Growth Hormone Receptor Are Not Required for the Signaling of Proliferation or Jak-STAT Activation

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

Human Growth Hormone and Extracellular Domain of Its Receptor: Crystal Structure of the Complex

1992 • 2,236 citations

Growth hormone receptor and serum binding protein: purification, cloning and expression

1987 • 1,540 citations

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

1993 • 988 citations

Dimerization of the Extracellular Domain of the Human Growth Hormone Receptor by a Single Hormone Molecule

1991 • 879 citations

An Interleukin-4-Induced Transcription Factor: IL-4 Stat

1994 • 856 citations

The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction

1993 • 766 citations

Signaling by the cytokine receptor superfamily: JAKs and STATs

1994 • 659 citations

Rational Design of Potent Antagonists to the Human Growth Hormone Receptor

1992 • 633 citations

The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter.

1990 • 615 citations

Cytokine Receptors and Signal Transduction

1992 • 607 citations

Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-& gamma; signal transduction pathway

1993 • 548 citations

A new cytokine receptor superfamily

1990 • 506 citations

Ligand-induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91).

1994 • 453 citations

Mode of Action of Pituitary Growth Hormone on Target Cells

1985 • 452 citations

Receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3, and interleukin-5

1993 • 404 citations

Tyrosine Phosphorylation of DNA Binding Proteins by Multiple Cytokines

1993 • 367 citations

Receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3, and interleukin-5

1993 • 318 citations

Growth hormone induces a DNA binding factor related to the interferon-stimulated 91-kDa transcription factor.

1994 • 179 citations

Acute phase response factor and additional members of the interferon-stimulated gene factor 3 family integrate diverse signals from cytokines, interferons, and growth factors.

1994 • 162 citations

Rapid changes in nuclear protein tyrosine phosphorylation after growth hormone treatment in vivo. Identification of phosphorylated mitogen-activated protein kinase and STAT91.

1994 • 123 citations

Mutational analysis of the intracellular domain of the human growth hormone receptor

1993 • 120 citations

Growth hormone promoted tyrosyl phosphorylation of growth hormone receptors in murine 3T3-F442A fibroblasts and adipocytes

1988 • 109 citations

Identification of a functionally important sequence in the C terminus of the interferon-gamma receptor.

1992 • 102 citations

Evidence for involvement of the growth hormone receptor-associated tyrosine kinase in actions of growth hormone.

1993 • 101 citations

Growth hormone and erythropoietin differentially activate DNA-binding proteins by tyrosine phosphorylation.

1994 • 91 citations

Phosphorylation of Highly Purified Growth Hormone Receptors by a Growth Hormone Receptor-associated Tyrosine Kinase

1989 • 89 citations

Signal transduction mediated by growth hormone receptor and its chimeric molecules with the granulocyte colony-stimulating factor receptor.

1993 • 77 citations

Stimulation of tyrosine phosphorylation in human cells by activation of the growth hormone receptor.

1993 • 69 citations

Mutational analysis of a critical signaling domain of the human interleukin 4 receptor.

1994 • 47 citations

Human growth hormone (GH) receptor is characterized as the 134-kilodalton tyrosine-phosphorylated protein activated by GH treatment in IM-9 cells.

1993 • 37 citations

Evidence for association of the cloned liver growth hormone receptor with a tyrosine kinase.

1992 • 34 citations

Growth hormone induces the tyrosine phosphorylation and nuclear accumulation of components of the ISGF3 transcription factor complex

1994 • 10 citations